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Selected Publications
Alt, J.R., Cleveland, J.L., Hannink, M., and Diehl, J.A. Phosphorylation-dependent regulation of cyclin D1 nuclear export and cyclin D1-dependent cellular transformation. Genes & Development, 14:3102-3114. (2000).
Gladden, AB and Diehl, JA. The Cyclin D1-dependent kinase associates with the pre-replication complex and modulates RB.MCM7 binding. J Biol Chem, 278:9754-9760. 2003.
Cullinan, SB, Zhang, D. Hannink, M, Arvisais, E, Kaufman, RJ, Diehl, JA. Nrf2 is a direct PERK substrate and effector of PERK-dependent cell survival. Mol Cell Biol. 23:7198-7209. 2003.
Lu, F, Gladden, AB, Diehl, JA. The alternatively spliced cyclin D1 isoform, cyclin D1b, is a nuclear oncogene. Cancer Research. 63:7056-7061. 2003.
Gladden, AB and Diehl, JA. Cell cycle progression without cyclin E/CDK2: breaking down the walls of dogma. Cancer Cell. 4:160-162. 2003.
Cullinan, SB, Jin, J, Harper, JW, and Diehl, JA. The Keap1-BTB protein is an adaptor that bridges Nrf2 to a Cul3-based E3 ligase: oxidative stress sensing by a Cul3-Keap1 ligase. Mol Cell Biol. 24:8477- 8486. 2004.
Lin, DI and Diehl, JA. Mechanism of Cell Cycle Control: Ligating the Ligase. TIBS. 29:453-455. 2004.
Hamanaka, RB, Bennett, BS, Cullinan, SB, Diehl JA. PERK and GCN2 contribute to eIF2 alpha phosphorylation and cell cycle arrest following activation of the Unfolded Protein Response Pathway. Mol Biol Cell. 16:5493-5501. 2005.
Gladden AB, Woolery R, Aggarwal, P, Wasik MA, Diehl JA. Expression of constitutively nuclear cyclin D1 in murine lymphocytes induces B-cell lymphoma. Oncogene. 25:998-1007. 2006.
Lin, DI, Barbash, O, Kumar, KGS, Weber, JD, SJ, Harper, JW, Klein-Szanto, AJP, Rustgi, A, Fuchs, SY, Diehl, JA. Phosphorylation-dependent ubiquitination of cyclin D1 by the SCFFBX4-alphaBcrystallin complex. Mol Cell. 24:355-366. 2006.
Bobrovnikova-Marjon, E and J. Alan Diehl. Coping with Stress: ATF6 takes the stage. Dev Cell. 13:322-324. 2007.
Aggarwal P, Lessie M, Lin DI, Gladden AD, Nuskey B, Goradia A, Wasik M, Klein-Szanto A, Rustgi A, Bassing C and Diehl JA. Nuclear Accumulation of Cyclin D1 During S-phase InhibitsCul4-dependent Cdt1 Proteolysis and Triggers p53-dependent DNA Re-replication. Genes & Dev. In press. |
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