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The Role of Reelin pathway in brain development |
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Description: A postdoctoral fellow position is available in the laboratory of Dr. Tom Curran at The Joseph Stokes, Jr. Research Institute of The Children's Hospital of Philadelphia , an interdisciplinary institution dedicated to conducting basic, clinical and translational research on conditions and diseases that affect children. The postdoc will investigate the role of the Reelin pathway in brain development. Since the discovery of Reelin (D'Arcangelo et al., Nature 1995), several molecular components of a complex signaling pathway that controls cell positioning during brain development have been uncovered. We are using a combination of molecular, biochemical, cell biological and genetic approaches to unravel the mechanisms responsible for shaping the mammalian brain.
Qualifications: Applicants must have a doctoral degree in biomedical sciences and a strong background in either molecular biology or neuroanatomy. Additional experience with mouse genetics is desirable.
Contact: Dr. Tom Curran
Interested individuals should submit their resume, cover letter and list of publications to cur_admin@chop.edu.
Postdoctoral fellows at The Children's Hospital of Philadelphia receive mentored training in a rich scientific and collaborative environment that includes the resources of the adjacent University of Pennsylvania. Visit www.stokes.chop.edu for more information about The Joseph Stokes, Jr. Research Institute and its research programs.
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| 2) |
The Role of the Sonic Hedgehog (Shh) pathway in human and mouse medulloblastoma |
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A postdoctoral fellow position is available in the laboratory of Dr. Tom Curran at The Joseph Stokes, Jr. Research Institute of The Children's Hospital of Philadelphia , an interdisciplinary institution dedicated to conducting basic, clinical and translational research on conditions and diseases that affect children. The postdoc will investigate the role of the sonic hedgehog (Shh) pathway in human and mouse medulloblastoma. Previously, we used mouse models, tumor cell culture and xenografts to study the propagation of brain tumor cells. Our goal is to identify potential new targets and therapeutic approaches for pediatric brain tumors.
Qualifications: Applicants must have a doctoral degree in biomedical sciences and a strong background in either molecular biology or mouse genetics. Additional experience with genomics is desirable.
Contact: Dr. Tom Curran
Interested individuals should submit their resume, cover letter and list of publications to cur_admin@chop.edu.
Postdoctoral fellows at The Children's Hospital of Philadelphia receive mentored training in a rich scientific and collaborative environment that includes the resources of the adjacent University of Pennsylvania. Visit www.stokes.chop.edu for more information about The Joseph Stokes, Jr. Research Institute and its research programs.
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| 3) |
Investigating signaling pathways regulating natural killer T (NKT) cell development and activation |
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A position for a post-doctoral fellow in the laboratory of Kim Nichols, M.D. in the Division of Oncology at the Children's Hospital of Philadelphia. The post doc candidate will investigate signaling pathways regulating natural killer T (NKT) cell development and activation. Our laboratory is using a combination of molecular, biochemical and mouse genetic approaches to unravel the mechanisms by which the adaptor molecule SAP controls NKT cell ontogeny and function.
Qualifications: Applicants must have a doctoral degree in biomedical sciences and a strong background in cellular and molecular immunology. Experience with mouse genetic is desirable.
Contact: Kim Nichols, M.D., University of Pennsylvania, BRB II/III Room 413, 421 Curie Blvd., Philadelphia, PA 19104; (215) 746-5546 (tel); nicholsk@email.chop.edu.
Interested individuals should submit their CV, cover letter, and letters of reference from 2-3 prior employers who can attest to competency and skills in research to nicholsk@email.chop.edu. |
