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Selected Publications
Mack, F., W. K. Rathmell, A. M. Arsham, J. Gnarra, B. Keith, and M. C. Simon (2003) Loss of pVHL is sufficient to cause HIF dysregulation in primary cells but does not promote tumor growth. Cancer Cell 3:75-88.
Dahl, R., J. C. Walsh, D. Lancki, P. Laslo, S. R. Iyer, H. Singh, and M. C. Simon (2003) Regulation of macrophage and neutrophil cell fate by the PU.1:C/EBPα ratio and granulocyte colony-stimulating factor. Nature Immunology 4:1029-1036.
Mansfield, K. D., R. D. Guzy, Y. Pan, R. M. Young, T. P. Cash, P. T. Schumacker, and M. C. Simon (2005) Mitochondrial dysfunction resulting from loss of cytochrome c impairs cellular oxygen sensing and hypoxic HIF- a activation. Cell Metabolism 1 :393-399. previewed in this issue
Liu, L., T. P. Cash, R. G. Jones, B. Keith, C. B. Thompson, and M. C. Simon (2006) Hypoxia induced energy stress regulates mRNA translation and cell growth. Molecular Cell 21:521-531.
Covello, K. L., J. Kehler, H. Yu, J. D. Gordan, A. M. Arsham, C. J. Hu, P. A. Labosky, M. C. Simon,* and B. Keith (2006) HIF-2 a regulates Oct-4: effects of hypoxia on stem cell function, embryonic development and tumor growth. Genes & Dev. 20:557-570.
Ramirez-Bergeron, D. L., A. Runge, D. Adelman, M. Gohil, and M. C. Simon (2006) HIF regulated hematopoietic signals regulate the development of embryonic vasculature. Dev. Cell, in press. |
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