Developmental Core Pilot and Feasibility Program Grant Recipients

Year

Principal Investigator(s)

Title of Pilot Project

2009

Stefania Gallucci, M.D.(Pediatrics), and David Weiner, Ph.D. (Path/Lab Medicine)

Clonogenic Progenitors of Dendritic Cells as Novel Antigen Carrier in anti-HIV

2009

Toorjo Ghose, M.S.W., Ph.D. (Social Policy & Practice)

Implementing PATH-India: Reducing HIV Risk Among the Dually Diagnosed in India

2009

John Kempen, M.D, M.H.S., M.P.H., Ph.D. (Opthalmology), and Maureen Maguire, Ph.D. (Opthalmology)

Pilot Study in Preparation for the Intravitreous Ganciclovir-Valganciclovir Cytomegalovirus Retinitis Trial (GIVCyT)

2009

Steven Marcus, Ph.D. (Social Policy & Practice), and Julie Cederbaum, M.S.W.,M.P.H. (Social Policy & Practice)

HIV Serostatus and its Influence on Mother Influence Behaviors and Adolescent Engagement in HIV Risk Behaviors

2009

Dooreen Ramogola, M.D. (Women's Health, University of Botswana), and Harvey Friedman, M.D. (Medicine, ID)

Epidemiology of HPV Infection in HIV-infected Women with Precancerous Cervical Lesions in Botswana

2009

Samir Shah, M.D., M.S.C.E.. (Pediatrics, Epidemiology), and Zsofia Szep, M.D. (Medicine, ID)

Association of Serum Vitamin D Levels and Insulin Resistance Among Patients Infected w/Human Immunodeficiency Virus

2008

Frederic Bushman, Ph.D. (Microbiology)

The Macaque Gut Microbiota and SIV Infection

2008

Branch Coslett, M.D. (Neurology) and Kathy Lawler, M.D. (Neurology)

Assessment of HIV-Related Dementia and Depression in Botswana

2008

Roy Kim, M.D. (Pediatrics) and Ian Frank, M.D. (Medicine, ID)

Effects of Recombinant IGF-I in HIV-Associated Metabolic Disease

2008

Susan Ross, Ph.D. (Microbiology)

Development of an in vivo Model to Study APOBEC3G/vif Interaction

2008

Courtney Schreiber, M.D. (OB/GYN)

How to Avoid Pregnancies in HIV Prevention Trials: a Case-Control Study and Point-of-Care Questionnaire

2008

Anne Teitelman, Ph.D. (Nursing); Loretta Sweet Jemmott, Ph.D. (Nursing); Therese S. Richmond, Ph.D. (Nursing); and William Holmes, M.D. (Medicine/Epidemiology)

HIV/STI Risk Reduction for African-American Adolescent Girls: Addressing the Context of Partner Abuse

2007

John B. Jemmott, III, Ph.D. (Annenberg School of Communication) and G. Anita Heeren, M.D., MSc., Ph.D. (Annenberg School of Communication)

HIV/STI Risk Reduction for African American Men

2007

Shane T. Jensen (Statistics, Wharton) and Jon D. McAuliffe (Statistics, Wharton)

Spatially Varying Evolutionary Models of Viral Escape Response

2007

Dennis Kolson, M.D., Ph.D. (Neurology) and Julio Martin-Garcia, Ph.D. (Microbiology/Immunology, Drexel)

Neurotropism and Neurovirulence of Subtype C HIV-1 Isolates from Botswana

2007

Ian C. MacMillan, MBA, DBA (Wharton); Darren Linkin, M.D. (Medicine, ID); James Thompson, MBA (Wharton); Alan Abrahams, Ph.D. (Wharton); Diana Dickinson, M.D. (Clinician in Gaborone, Botswana); and Peter Ehrenkranz, M.D., MPH (Clinical Scholars, Penn)

A Pilot Study of Cellular Phone Text Message Reminders to Improve HIV Medication Adherence in the Developing World

2007

Erle Robertson, Ph.D. (Microbiology) and Gregory Bisson, M.D., M.S.C.E. (Medicine, ID), Co-PI

Identification of an Etiological Basis Associated with Ocular Surface Squamous Neoplasia

2007

Guido Silvestri, M.D. (Pathology and Laboratory Medicine) and Ian Frank, M.D. (Medicine, ID), Co-PI

Mucosal Immune Activation in HIV-infected Patients

2006

Yair Argon, Ph.D. (Pathology and Laboratory Medicine) and Stefania Gallucci, M.D. (Pediatrics, Children's Hospital)

Augmenting the Presentation of HIV Peptides to T cells using an Engineered Chaperone Protein

2006

Michael Betts, Ph.D. (Microbiology) and Ian Frank, M.D. (Medicine, ID), Co-PI

Modulation of HIV-specific CD8+ T cell Function and Control of HIV Replication During and After Cessation of HAART  

2006

Arthur Caplan, Ph.D. (Medicine, Medical Ethics)

An Ethical Framework for HIV Vaccine Research

2006

Sridhar Hannenhalli, Ph.D. (Genetics) and Frederic Bushman, Ph.D. (Microbiology)

Computational Analysis of HIV-1 Integration in the Human Genome

2006

Nancy Hanrahan, Ph.D. (School of Nursing)

Quantifying Nurse Interventions in the Treatment of Individuals with Serious Mental Illness and HIV

2005

Randy Cron (Pediatrics, Children's Hospital) and Pablo Tebas (Penn Medicine, ID), Co-PI

NFAT Activity in CsA-Treated HIV-1-Infected Individuals

2005

Stefania Gallucci (Pediatrics, Children's Hospital) and Terri Finkel (Pediatrics, Children's Hospital)

Activating Anti-HIV Dendritic Cells by Abnormal Cell Death

2005

Edward George (Statistics, The Wharton School)

Exploratory Markov Modeling of Discrete Biomarkers

2005

David Oslin (Psychiatry)

Aging Among HIV-infected Individuals as a Risk for Cognitive Decline and Poor Adherence

2005

Pablo Tebas (Medicine, ID)

Prevalence of HCV and HBV Among HIV Positive Patients in the Dominican Republic

2004

Harvey Friedman (Medicine, ID) and Gregory Bisson (Medicine, ID)  

Virologic Effectiveness, Predictors of Virologic Failure and Development of a Clinical Prediction Rule for Virologic Success in the Botswana National ARV Program

2004

John Detre (Neurology) and Beau Ances (Neurology)

Brain Activation Using fMRI in Asymptomatic, Mild Cognitive Motor Deficit, and AIDS Dementia Patients  

2004

Muredach P. Reilly (Medicine, Cardiovascular Division)  

Pilot Study of the Genetics of ART-associated Dyslipidemia in HIV

2004

Hao Shen (Microbiology)  

Role of CD4 Help in Heterologous Prime-Boost Immunization

2003

Li-Wei Chao (Anesthesiology, Children's Hospital) and Mark Pauly (The Wharton School)

Educator and Pupil Training in HIV/AIDS in South Africa

2003

Andrew Dancis (Medicine, Hematology/Oncology)

Roles for Three Distinct Iron Uptake Systems in Mucosal Infections by Candida albians

2003

Paul Lieberman (The Wistar Institute)

Regulation of Kaposi's Sarcoma-Associated Virus Reactivation

2003

Gerd Maul (The Wistar Institute)

Improvement for Gag DNA Vaccine Vector by Nuclear Targeting

2003

Barbara Turner (Medicine) and Kathleen Brady (Medicine)

Unlinked Seroprevalence Testing of Hepatitis C in Inpatients

2002

Jean Boyer (Pathology and Laboratory Medicine)  

A Polarized Th2 Immune Response Can Decrease HIV-1 Vaccine Efficacy

2002

Robert Doms (Microbiology)

Analysis of Envs from HIV-infected Children in Nairobi, Kenya

2002

J. Kevin Foskett (Physiology)

Interaction of HIV Nef with the Inositol Trisphophate Receptor Intracellular Ca2 Release Channel

2002

Kaivan Munshi (Economics, School of Arts and Sciences)

Marriage and Sexual Behavior: With an Application to Urban Migrants in Kisumu, Kenya

2002

James Riley (Pathology and Laboratory Medicine)

Control of CCR5 Expression in Primary CD4 T Cells

2001

Michael Blank (Psychiatry) and Aileen Rothbard (Psychiatry)

Co-Occurrence of HIV/AIDS Among Persons with Severe Mental Illness

2001

Bruce Freedman (Animal Biology, School of Veterinary Medicine)

Mechanism of HIV-1 gp120 Induced Capping on Primary Human Macrophages

2001

Samuel Parry (Center for Research on Reproduction and Women's Health)

Transmission of Human Immunodeficiency Virus Across the Placenta

2001

William Swiggard (Medicine, ID)

Interactions of Circulating Human Dendritic Cells with HIV-1

2000

Jeffrey Field (Pharmacology)

Role of Pak kinases in Kaposi's Sarcoma

2000

Stuart Isaacs (Medicine, ID)

Development of Novel Recombinant Vaccinia Virus Based anti-HIV Vaccines

2000

Robert Ricciardi (Microbiology, School of Dental Medicine)

A Novel Approach for Identifying HHV-8 Anti-virals

2000

Antonia Villarruel (School of Nursing)

Effectiveness of an HIV Risk Reduction Intervention for Spanish-speaking Latino Youth

2000

Susan Watkins (Sociology) and Jere Behrman (Economics)

Social Science Aspects of Intergenerational and Intragenerational Interactions Related to HIV/AIDS in a High HIV/AIDS Incidence sub-Saharan Population