Department of Biochemistry and Biophysics


Secondary Appointments

 

Paul H. Axelsen, M.D.
Associate Professor of Pharmacology
105 Johnson Pavilion
131 John Morgan Building
tel.: 215-898-9238
fax:  215-573-9135
email:  axe@pharm.med.upenn.edu

Biophysics of molecular recognition, seeking to understand how pharmacologically active molecules recognize their target sites of action, and how they accomplish their function after binding to their target site.

Kathleen Boesze-Battaglia, Ph.D.
Associate Professor
Department of Biochemistry, School of Dental Medicine
tel:  215-898-9167
fax:  215-898-3695
email:  battagli@biochem.dental.upenn.edu

Tetraspanin protein structure and role in degenerative disease processes.

Charles C. Clark, Ph.D.
Associate Professor of Orthopaedic Surgery
424 Stemmler Hall
tel.: 215-898-8440
fax: 215-573-2133
email: ccclark@mail.med.upenn.edu

Musculoskeletal biochemistry with emphasis on collagen and proteolgycan structure and metabolism

Fevzi Daldal, Ph.D.
Professor of Biology
103B Lynch Laboratory
tel.:  215-898-4394
fax: 215-898-8780
email:  fdaldal@sas.upenn.edu

Photosynthetic and respiratory electron transport chains in bacteria: structure, function, regulation and biogenesis of cytochromes and cytochrome complexes

Zoltan Domotor, Ph.D.
Professor of Philosophy, School of Arts and Sciences
433 Logan Hall
tel.: 215-898-6347
fax: 215-898-5576
email::  zdomotor@sas.upenn.edu

Methodology of scientific inquiry in biological research, theoretical foundations of biology, and applications of logical and probabilistic models in biology

Jerry D. Glickson, Ph.D.
Research Professor of Radiology
Laboratory of Molecular Imaging
B6 Stellar-Chance Labs
tel.:  215-898-1805
fax:  215-573-2113
email: glickson@mail.med.upenn.edu

The Laboratory of Molecular Imaging is developing NMR and optical imaging probes for the detection and/or treatment of cancer and heart disease and for elucidating metabolism and physiology in animal models of human disease and in human subjects.

Laboratory of Molecular Imaging homepage

Jonas S. Johansson, M.D., Ph.D.
Associate Professor of Anesthesia
319C John Morgan Building
tel.: 215-349-5472
fax:215-349-5078
email: JohanssJ@uphs.upenn.edu

Structural aspects of volatile general anesthetic binding sites on proteins and the effects of bound anesthetic on protein structure and dynamics.
Johannson C.V. in pdf format

Nicholas A. Kefalides, M.D., Ph.D.
Professor Emeritus of Medicine
Connective Tissue Research Institute
3701 Market Street, Rm. 468
Science Center Port
tel.: 215-966-6102
fax: 215-966-6101
email: kefalide@mail.med.upenn.edu

Biochemistry, cell biology and molecular biology of extracellular matrix

Trevor M. Penning, Ph.D.
Professor of Pharmacology
130C John Morgan Building
tel.: 215-898-9445/1186
fax: 215-573-2236
email: penning@pharm.med.upenn.edu

Structure-function of aldo-keto reductases (genes and enzymes):  roles in steroid hormone action and chemical carcinogenesis

Ravi Radhakrishnan, Ph.D.
Assistant Professor of Engineering
310 Hayden Hall
tel: 215-898-0487
fax: 215-573-2071
email: rradhak@seas.upenn.edu

Computational biology; molecular origin of cancer, cancer therapeutics and drug delivery using theoretical and computational tools at the molecular and system level

Norman M. Schechter, Ph.D.
Research Professor of Dermatology
240 Clinical Research Building
tel.: 215-898-3680
fax: 215-573-2033
email: schechte@mail.med.upenn.edu

Understanding the structure, function and regulation of serine proteases from inflammatory cells.  Establishing the mechanism protease inhibition by proteins of the serpin family.

Felix W. Wehrli, Ph.D.
Professor of Radiology
1 Founders Pavilion
tel.: 215-662-7951
fax: 215-349-5925
email: wehrli@oasis.rad.upenn.edu

MRI of tissue microstructure and function, mathematical modeling, image processing

Frank A. Welsh, Ph.D.
Professor of Biochemistry in Surgery
371 Stemmler Hall
tel.: 215-662-7925
fax:  215-349-8157
email: fwelsh@mail.med.upenn.edu

Molecular mechanisms of ischemic brain damage; pathways of inducible neuroprotection