Thursdays at 12:00 noon
Austrian Auditorium, Clinical Research Building
Spring 2012
January 12
 Haixin Sui (Wadsworth Center and University at Albany, SUNY)
Cryo-electron microscopy of microtubule machinery
January 19
 Peter M. Tessier (Rensselaer Polytechnic Institute)
Antibodies by design
January 26
 Peter D. Kwong (NIAID, National Institutes of Health)
Antibodies, lineages and an HIV-1 vaccine
February 2
 Adam E. Cohen (Harvard University)*
Imaging voltage in cells: from neurons to E. coli
February 9
 Doryen Bubeck (Oxford University)
Assembly and regulation of the membrane attack complex based on the structures of complement components
February 16
 Geeta J. Narlikar (University of California, San Francisco)
Mechanistic analysis of heterochromatin assembly: A tale of how recognizing oneself helps recognize others
March 1
 Zhihao Zhuang (University of Delaware)
Chemistry and biology of eukaryotic translesion synthesis
March 8
 Kristina M. Herbert (Yale University)
Mechanism and regulation of pri-miRNA processing
March 15
 Mark R. Chance (Case Western Reserve University)
Structural mass spectrometry of protein complexes and membrane proteins
March 22
 Peter J. Hore (Oxford University)*
Do birds have a chemical magnetic compass?
March 29
 Ruben L. Gonzalez, Jr. (Columbia University)
Directing nature’s random walks: biological mechanisms, one molecule at a time
April 5
 Ernesto Freire (Johns Hopkins University)*
The thermodynamics of binding affinity and selectivity
April 12
 Jason E. Gestwicki (University of Michigan, Ann Arbor)
Strategies for targeting protein-protein interaction in heat shock protein 70 (Hsp70)
* student invited speaker
Please contact Angie Young at 215-898-4639 or younga@mail.med.upenn.edu for additional information