Thursdays at 12:00 noon
Austrian Auditorium, Clinical Research Building
January 17
 Svetlana Lutsenko (Oregon Health & Science University)
Molecular mechanisms of copper transport in healthy and diseased tissues
January 24
 Tatiana Kutateladze (University of Colorado)
Histone and phosphoinositide codes
January 31
 Art Horwich (Yale University)
Protein folding by chaperonins and misfolding in ALS
February 7
 Jeff Kelly (The Scripps Research Institute)
Restoring protein homeostasis to ameliorate loss- and gain-of-function diseases
February 14
 Brian Crane (Cornell University)*
Macromolecular assemblies and conformational coupling in bacterial chemotaxis
and circadian clock light sensing
February 21
 Donald M. Engelman (Yale University)*
Mechanism and uses of transmembrane peptide insertion to image tumors and deliver drugs
February 28
 Tim Mitchison (Harvard University)
Imaging and pharmacology of the mitotic spindle
March 6
 Junying Yuan (Harvard University)
A quest to understand the mechanisms of neurodegeneration
March 20
 Susan Marqusee (University of California, Berkeley)
Manipulating a protein's energy landscape
March 27
 Ulrich Hartl (Max Planck Institute, Martinsried)
Mechanisms of chaperone-assisted protein folding
April 3
 Kathleen Hall (Washington University, St. Louis)
Mechanisms of RNA binding by the RNA Recognition Motif (RRM) protein domain
April 10
 Yizhi Jane Tao (Rice University)
Structural insights into genome packaging and RNA synthesis by influenza A viruses
April 17
 Michael Levitt (Stanford University)
Mesoscale modeling of macromolecular machines
April 24
 Jim Wells (University of California, San Francisco)
Triggering and tracking cell death
May 1
 David Allis (The Rockefeller University)
Beyond the double helix: writing and reading the "histone code"
May 8
 Linda Nicholson (Cornell University)
From the NMR tube to living systems: relating protein dynamics to the dynamic regulation of cellular processes
May 15
 Kristen Lynch (University of Texas Southwestern)
Signal-induced alternative splicing in the immune system
* student-invited talks
Please contact Angie Young at 215-898-4639 or younga@mail.med.upenn.edu
if you wish to meet with any speaker