University of Pennsylvania Medical Center Guidelines for Antibiotic Use
It is very difficult, if not impossible, to eradicate colonization with resistant organisms (vancomycin-resistant enterococci "VRE or VREF", oxacillin-resistant S. aureus "ORSA or MRSA", or multi-drug-resistant Gram-negative bacteria). For this reason, all patients infected or colonized with such bacteria are to remain in appropriate isolation until hospital discharge. The Clinical Microbiology Laboratory will not accept surveillance cultures from such patients designed to remove the patients from isolation, unless approved in advance by the Infection Control Department.
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