Antimicrobial Dosage Regimens
Drug |
Dosage Regimen |
Amikacin |
15mg/kg x1 (round to the nearest 50mg increment) click here to determine subsequent doses |
Aztreonam* |
2gm IV q 8 hr |
Cefepime* |
1gm IV q 8 hr |
Levofloxacin* |
750mg IV q 24 hr |
Metronidazole |
500mg IV q 12hr |
Vancomycin |
≤ 70kg = 1 gm x 1, > 70kg = 1.5gm x 1 click here to determine subsequent doses |
*Dosage adjustments required with renal dysfunction.
Antimicrobial Administration and Compatibility
|
Infusion time |
Not compatible |
Amikacin |
30 minutes |
Metronidazole |
Aztreonam |
15 minutes |
Vancomycin, metronidazole |
Cefepime |
IV push over 5 minutes |
Vancomycin |
Levofloxacin |
500 mg- 60 minutes 750 mg- 90 minutes |
Compatible with all agents coadministered per algorithm |
Metronidazole |
30 minutes |
Aztreonam, amikacin |
Vancomycin |
60 minutes for 1 gram 90 minutes for > 1 gram |
Aztreonam, cefepime |
Reference: Trissel’s™2 Clinical Pharmaceuticals Database (Parental Compatibility)
Updated 3/09
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