University of Pennsylvania Medical Center Guidelines for Antibiotic Use

Antimicrobial Susceptibilities of Obligately Anaerobic Bacteria Performed 11/06 on Bacterial Isolates Collected from 2003 to 2006#

% Susceptible - Etest, NCCLS M11-A4 guidelines

Bacterium No. Tested Pen G A/C Mero Metro Clinda Vanco
 Breakpoint    <1 <8/4 <8 <16 <4 <2
B. fragilis group 101 NT* 92 99 100 32 NT*
Clostridium 23 74 100 NT 96 61 NT
Gram-pos cocci (Peptostreptococcus) 10 90 100 NT NT* 80 100
Pigmented Gram-neg rods (Prevotella, Porphyromonas) 9 NT* 100 NT 100 78 NT*
Fusobacterium 15 100 100 NT 100 93 NT*
P. acnes 21 100 NT NT NT* 100 100
Veillonella 7 14 100 NT 100 100 NT*

# Most B fragilis group isolates are from 2006

Pen G - Penicillin G, A/C - Amoxicillin/clavulanate, Mero - Meropenem, Metro - Metronidazole, Clinda - Clindamycin, NT - not tested, * - resistance common to this drug for this bacterium

updated 1/12/07 P. Edelstein

Back to Table of Contents