University of Pennsylvania Medical Center Guidelines for Antibiotic Use

Antimicrobial Susceptibilities of Obligately Anaerobic Bacteria Performed 4/2001 on Bacterial Isolates Collected from 1997 to 2000

% Susceptible - Broth Microdilution, NCCLS M11-A4 guidelines

Bacterium No. Tested Pen G A/S Metro Clinda Chloro Cefox Cefotet Imi Pip Tet
 Breakpoint    <1 <16/8 <16 <4 <16 <32 <32 <8 <64 <8
B. fragilis 39 0 100 100 46 100 74 44 100 59 31
Clostridium 12 100 100 100 83 100 100 100 100 100 83
Gram-pos cocci (Peptostreptococcus) 14 100 100 57 93 100 100 100 100 100 71
Pigmented Gram-neg rods (Prevotella, Porphyromonas) 9 11 100 100 77 100 100 88 100 100 44
Fusobacterium 4 100 100 100 100 100 100 100 100 100 100
P. acnes 9 100 100 0 88 100 100 100 100 100 100
Veillonella* 8 38 88 100 100 NT NT NT NT NT NT

* Tested only with selected agents

Pen G - Penicillin G, A/S - Ampicillin/sulbactam, Metro - Metronidazole, Clinda - Clindamycin, Chloro - Chloramphenicol, Cefox - Cefoxitin, Cefotet - Cefotetan, Tet- Tetracycline, Imi - Imipenem, Pip - Piperacillin

 

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