University of Pennsylvania Medical Center Guidelines for Antibiotic Use

 

CLINICAL MICROBIOLOGY LABORATORY

ANTIMICROBIAL SUSCEPTIBILITY PROFILES FOR THE HOSPITAL OF THE UNIVERSITY OF PENNSYLVANIA

January 2015 to March 2016 and Current Data

Antimicrobial susceptibility data for UPHS facilities is available from iAntibiogram; only those with UPHS IT access can view these pages. The iAntibiogram is updated frequently. Data can be sorted by patient location (hospital) and admission status (inpatient or outpatient). The cumulative susceptibility data in iAntibiogram displays either location specific or overall UPHS data, depending on whether the location specific data are significantly different from the total dataset. If the data are colored blue then you are seeing location specific data, and if black then global data. If you hover over iAntibiogram you can see more discrete data, including the N and % susceptibility for the specific location as well as for UPHS. The circled "i" at the left edge is a link to information about the drug, with red meaning drugs requiring approval. You can access a help screen by clicking on the circle in the upper right part of the screeen. The frequently updated iAntibiogram data only include bacteria, not Candida or mycobacteria. In addition, data for pneumococcus and anaerobes are static. You can find the static data (anaerobes, pneumococci, Candida and rapidly growing mycobacteria) below.

Archived and static susceptibility results are found in three tables, one for inpatients (archived), one for outpatients (archived) (HUP and PPMC combined) and the third for anaerobic bacteria (2014 combined data for HUP and PMC). The pneumococcal (Jan 2015-Mar 2016) Stenotrophomonas maltophilia, enteric pathogens (2011-2012- see iAntibiogram for current data), Candida species (Jan 2015-Mar 2016) and rapidly growing mycobacteria (2013-Mar 2016) susceptibility data for both institutions are now presented on a separate page.The emergence of multidrug resistant K. pneumoniae from 2001 to 2012 years is now shown. In general, the outpatient susceptibility results give a better picture of the frequency of antimicrobial agent resistance of community-acquired pathogens, and the inpatient results of hospital-acquired pathogens. Usually inpatient bacterial isolates are more resistant to antimicrobial agents than are outpatient isolates. However, in some cases, some outpatient clinics care for patients with chronic infections, who have been treated with multiple courses of antimicrobial agents; in this case the outpatient isolates may be more resistant than inpatient isolates.

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