University of Pennsylvania Medical Center Clinical Microbiology Laboratory Information and Non-UPHS Guidelines for Antimicrobial Therapy

The official UPHS Antimicrobial Therapy Guidelines have been moved to a new site. This site now contains UPHS Clinical Microbiology information, guidelines of national and international societies and other information useful to clinical microbiologists and infectious diseases specialists.

 

Click on Our Bug for HUP/UPPMC Antimicrobial Susceptibility Data

TABLE OF CONTENTS

 
Clinical Microbiology Laboratory  
Therapy Guidelines  
  Endocarditis and Endovascular Infections
  Fungal Infections
  Gastrointestinal Tract Infections
  Intraabdominal Infections
  Hepatitis
  Urinary Tract Infections
  Sexually Transmitted Diseases
  Infection Control and Immunization
  IDSA and BSAC Guidelines
  Pneumonia and Upper Respiratory Tract Infections
  Tuberculosis
  WHO and IUATLD TB Guidelines - Resource Poor
  Parasitic, Tick-borne, Travel-related Infections
  HIV
  Bioterrorism
   

 


New Postings

Updated IDSA guidelines for:

(all © by the Infectious Diseases Society of America)

Updated CDC/NIH guidelines for:


Clinical Microbiology Laboratory

Antimicrobial Susceptibilities at UPHS

HUP Antimicrobial Susceptibility Profiles for 2011 Jan-June 

Presbyterian Medical Center Susceptibility Profiles for 2011 Jan-June

Antimicrobial Susceptibility Testing and Interpretation & Drug Resistance

Antimicrobial Susceptibility of Rapidly Growing Mycobacteria

How to Interpret Susceptibility Results - What "S", "I", and "R" Means and How Testing is Performed

Eucast Expert Rules for Antimicrobial Susceptibility Test Interpretation (offsite pdf, 214 kb, 4/08)

Eucast Clinical Breakpoints (offsite link)

Drug Resistance Mechanisms and Prevalence

Problem bacteria at HUP (UPHS only)

Gram Stains - Method, Interpretation, and Atlas

All About Gram Stains and Gram Staining - Includes a Gram Stain Atlas

New Gram Stain Atlas

Mycobacteria

M. tuberculosis time to detection from culture (6/13)

Specimen Collection

Alphabetical guide to laboratory specimen collection for all types of laboratory tests at UPHS (UPHS only)

Guide to Specimen Collection for Biowarfare Agents(UPHS only)

Mumps testing guidelines from CDC (4/10)

Influenza Testing and Results Information (10/10)

Blood culture collection (2/11)

Problem Sets

Teaching lectures (UPHS only)

Problem sets (Registered Blackboard users only)

HIV Testing

HIV antibody testing methods used at HUP

Bacterial Taxonomy

Professor Euzeéby

Deutsche Sammlung von Mikroorganismen und Zellkulturen

Bioterrorism Agents

ASM Sentinel Laboratory Guidelines (offsite link)

CDC Infectious Diseases Testing

CDC infectious diseases laboratory test directory (offsite link) (2/13)

CDC specimen submission instructions and electronic submission form (offsite link) (8/14)

CDC special viral pathogen request form (Hemorrhagic fevers - Lassa, Ebola, etc.) (offsite link) (8/14)

Ebola Virus Status, Procedures and Guidelines

CDC Ebola Virus Information (offsite link) (8/14)

UK Ebola Virus Triage, Clinical Management, Testing Guidelines (offsite link)

UK Viral Hemorrhagic Fever Risk Assessment, Patient Managment, etc.- August 2014 (offsite link)

Australian Guidance - Laboratory Precautions for Patient Samples Suspected VHF, 2005 (offsite link Guidance for Labs Associated with Isolation Hospitals and for those without an association),( local file, association with an isolation hospital, 75kb pdf) (8/14)

WHO Ebola Virus Information (offsite link) (8/14)

Respiratory Virus Statistics Influenza for the Current Season UPHS, Pennsylvania, US and World

Pennsylvania Dept Health Influenza Activity

CDC Influenza Activity

WHO Influenza Activity

UPHS Winter 2013-Fall 2014 (updated weekly)

UPHS Winter 2012-Spring 2013

UPHS Winter 2011-Spring 2012

UPHS Winter 2010-Spring 2011


 

Guidelines and Information

Endocarditis and Endovascular Infections

Endocarditis Diagnosis and Management

AHA Diagnosis and Management of Infectious Endocarditis -1998 (link to AHA web page or link to offsite pdf file 168kb

AHA Infective Endocarditis (2005, offsite link)

BSAC Endocarditis Diagnosis and Treatment Guidelines -2012 (PubMed abstract) or off site pdf  ( 581 kb)

ESCMID, ISC Guidelines on the Prevention, Diagnosis and Treatment of Infective Endocarditis (2009, offsite 17 mb pdf)

Clinical Practice Guidelines by the Infectious Diseases Society of America for the Treatment of Methicillin-Resistant Staphylococcus Aureus Infections in Adults and Children (2010,pdf 370 kb) ©2011 by the Infectious Diseases Society of America

 

Endocarditis Prophylaxis

AHA Endocarditis Prophylaxis Guidelines - April 2007 (pdf, 602 kb, off site link)

BSAC Endocarditis Prophylaxis Guidelines - 2006 off site pdf (103 kb)

Modified Duke Criteria for Endocarditis

Nonvalvular Device Infections and Prophylaxis

AHA Nonvalvular Cardiovascular Device-Related Infections -2010 (link to offsite AHA pdf file or online version)

Guidelines for the Management of Intravascular
Catheter–Related Infections
(685 kb, pdf) 2009 by the Infectious Diseases Society of America

Guidelines For The Prevention Of Intravascular Catheter-Related Infections (August 2002; CDC, IDSA, SHEA, et al) (pdf file 340 kb) or link to CDC html file


Fungal Infections

Introduction to Antifungal Drugs (pdf, 33 kb), ©2000 by the Infectious Diseases Society of America 

Guidelines for Treatment of Fungal Infections (pdf, 57 kb), ©2000 by the Infectious Diseases Society of America 

ATS 2011 Treatment of Fungal Infections in Adult Pulmonary and Critical Care Patients (offsite pdf, 367kb, requires subscription until posted on ATS Website)

Treatment of Aspergillosis (pdf, 483 kb), ©2008 by the Infectious Diseases Society of America 

Management of Patients with Blastomycosis (pdf, 265 kb), ©2008 by the Infectious Diseases Society of America 

Treatment of Candidiasis (pdf, 480 kb), ©2009 by the Infectious Diseases Society of America 

Treatment of Coccidioidomycosis (pdf, 98 kb), ©2005 by the Infectious Diseases Society of America 

Management of Cryptococcal Disease (pdf, 461 kb), ©2010 by the Infectious Diseases Society of America 

Management of Patients with Histoplasmosis (pdf, 172 kb), ©2007 by the Infectious Diseases Society of America 

Management of Patients with Sporotrichosis (pdf, 120 kb), ©2007 by the Infectious Diseases Society of America

Dr. Fungus- A website with extensive information on fungi


Gastrointestinal Tract Infections

Diagnosis and Management of Foodborne Illnesses - CDC RR-4, Apr 2004 (offsite html or onsite pdf 368kb)

Practice Guidelines for the Management of Infectious Diarrhea -IDSA Jan 2001 (pdf 284 kb), 2001 by the Infectious Diseases Society of America

Treatment Guideance for Clostridium difficile Infections (ESCMID, 2009, offsite pdf)

Clinical Practice Guidelines for Clostridium difficile Infections in Adults - 2010 Update (IDSA-SHEA, offsite pdf)

Cholera Management for Haitian Outbreak (CDC Dec 2010 pdf 144kb, offsite html)


 

Intraabdominal Infections

Diagnosis and Management of Complicated Intra-abdominal Infection in Adults and Children, Surgical Infection Society, IDSA 2010 ( pdf, 732 kb) ©2010 by the Infectious Diseases Society of America 

Surgical Infection Society Link to Guidelines

2005 Guidelines from the International Society of Peritoneal Dialysis for the Diagnosis and Management of Peritoneal Dialysis-Associated Peritonitis

Updated (2010) ISPD Guidelines for Peritoneal Dialysis Related Infections (3/2011)


Hepatitis

Chronic Hepatitis B Antiviral Treatment Guidelines Amer Assoc Study Liver Dis Guidelines 2009 (offsite pdf, 500 kb)

Chronic Hepatitis C type 1 treatment- Amer Assoc Study Liver Dis Guidelines 2011 (offsite pdf, 420 kb)

Diagnosis, Management and Treatment of Hepatitis C Infections AASLD & IDSA 2014 Website (offsite link)


Urinary Tract Infections

Diagnosis and treatment of asymptomatic bacteriuria in adults - IDSA, ASN, AGA, March 2005 ©2005 by the Infectious Diseases Society of America pdf 133 kb

2010 International Practice Guidelines for Antimicrobial Treatment of Acute Uncomplicated Cystitis and Pyelonephritis in Women (pdf, 240 kb), ©2011 by the Infectious Diseases Society of America

Diagnosis, Prevention, and Treatment of Catheter- Associated Urinary Tract Infection in Adults, 2009, IDSA pdf, (469 kb), ©2010 by the Infectious Diseases Society of America


Sexually Transmitted Diseases

CDC December 2010 Guidelines for the Treatment of Sexually Transmitted Diseases (pdf 1.1mb)

See also Hepatitis and HIV sections


Guidelines for Infection Control and Immunization

Infection Control Guidelines

UPHS Infection Control Policies (UPHS Intranet only)

CDC Guidelines for the Prevention of Nosocomial Pneumonia (2003 published Mar04 offsite html link or onsite pdf file (811kb)

Guidelines for Preventing Infectious Complications among Hematopoietic Cell Transplantation Recipients: A Global Perspective (ASBMT, IDSA, 2009) pdf file 1.4 mb

HICPAC Guidelines for the Prevention of Intravascular Catheter-Related Infections, 2011, pdf 1.0 mb

Guidelines for the Prevention of Perinatal Group B Streptococcal Disease (Nov 2010; CDC) pdf file 1.6 MB

CDC-HICPA Guidelines for Environmental Infection Control in Health-Care Facilities (June 2003) link to pdf file (1 MB) or html document

HICPAC Guideline for Isolation Precautions: Preventing Transmission of Infectious Agents in Healthcare Settings, 2007  (6/07, 1.3 mb pdf)

CDC- Prevention of TB Transmission in Health Care Facilities, Dec 2005 (pdf 1.2 mb)

Guideline for Hand Hygiene in Healthcare Settings (October 2002; CDC) pdf file 506kb or link to CDC html file

Updated Norovirus Outbreak Management and Disease Prevention Guidelines (CDC, 3/11) pdf 850kb

Post-exposure Prophylaxis

CDC guidelines for postexposure prophylaxis for occupational HIV, HBV, and HCV (August 2001, pdf, 343kb)

CDC guidelines for occupational HIV postexposure prophylaxis (2013, offsite link)

CDC guidelines for postexposure prophylaxis for sexual, injection drug and other nonoccupational HIV exposure (Jan 2005, pdf 112kb)

CDC ACIP guidelines for postexposure hepatitis A prophylaxis (Oct 2007, offsite link)

CDC guidelines for postexposure non-occupational hepatitis B prophylaxis (2006, offsite link)

CDC Guidance for Evaluating Health-Care Personnel for Hepatitis B Virus Protection and for Administering Postexposure Management (2006, pdf 712 kb)

CDC guidelines for HBV, HCV, HIV, Tetanus Postexposure prophylaxis after bombing or other mass-casualty event (August 2008, pdf 263kb)

Tetanus guidelines, including passive and active immunization after injury CDC 2012 pink book, pdf

Immunization

ACIP guidelines (updated automatically via CDC server)

ACIP (external link to CDC website)

ACIP Seasonal Influenza Vaccination Guidelines, 10/2013, pdf 690 kb

Adult Immunization Schedule 2013, ACIP pdf file 347kb

ACIP Immunization Schedule for Persons 0-18 Years of Age, Jan 2013, (pdf 1 mb)

Guidelines for the Vaccination of Immunocompromised Hosts 2013, IDSA, pdf file 572 kb, ©2013 by the Infectious Diseases Society of America

Meningococcal disease prevention by immunization, CDC 2013, pdf

Pneumococcal vaccine guidelines older adults, CDC, 2014, pdf

Pertussis Treatment and Postexposure Prophylaxis, CDC, Dec 2005, pdf file 210kb

Smallpox vaccination and adverse Reactions (Jan 2003; CDC) link to pdf file (13MB) or html document

ACIP-HICPAC Use of Tdap (Tetanus, reduced diphtheria toxoid, acellular pertussis) Vaccine in Adults, 2012 (pdf 412 kb)

ACIP Use of Tdap in Pregnant Women 2012 pdf

ACIP Immunization of Health Care Personnel, Nov 2011, (pdf 722 kb)

CDC Guidance for Evaluating Health-Care Personnel for Hepatitis B Virus Protection and for Administering Postexposure Management (2006, pdf 712 kb)

Surgical Prophylaxis

Antimicrobial Prophylaxis for Surgery IDSA/ASHP/SIS/SHEA Feb 2013 (offsite link pdf 1 mb)

Prevention of Infections Associated with Combat Injuries SIS, IDSA August 2011 (offsite pdf link 860 kb)

Communicable Disease Reporting

Reporting communicable diseases in Philadelphia (external link to Philadelphia Dept. of Public Health Division of Disease Control)


 

Infectious Diseases Society of America and British Society for Antimicrobial Chemotherapy Guidelines

IDSA Guidelines in iPhone and iPad format

2010 Guidelines for the Use of Antimicrobial Agents in Neutropenic Patients with Cancer (pdf, 518 kb) or link to IDSA guidelines ©2011 by the Infectious Diseases Society of America 

Guidelines for evaluation of new fever in critically ill adult patients: 2008 Amer. Coll. Crit. Care
Med. & IDSA
(offsite pdf, 198 kb)

Fungal Infections

The Clinical Assessment, Treatment, and Prevention of Lyme Disease, Human Granulocytic Anaplasmosis, and Babesiosis - IDSA Oct 2006, pdf 2.8 mb Excellent update of guidelines ©2006 by the Infectious Diseases Society of America

Practice Guidelines for Outpatient Parenteral Antimicrobial Therapy (pdf 189 kb, June 2004), ©2004 by the Infectious Diseases Society of America

Diagnosis and Treatment of Diabetic Foot Infections (pdf 455 kb, May 2012) ©2012 by the Infectious Diseases Society of America

Practice Guidelines for the Management of Bacterial Meningitis (pdf 319kb, Nov 2004) ©2004 by the Infectious Diseases Society of America

Practice Guidelines for the Diagnosis and Management of Skin and Soft Tissue Infections (pdf 313 kb, Nov 2005) ©2005 by the Infectious Diseases Society of America

Guidelines for the prophylaxis and treatment of methicillin-resistant Staphylococcus aureus ( MRSA) infections in the UK- BSAC Working Party offsite link (230 kb, pdf) (2/06)

Clinical Practice Guidelines by the Infectious Diseases Society of America for the Treatment of Methicillin-Resistant Staphylococcus Aureus Infections in Adults and Children (2010,pdf 370 kb) ©2011 by the Infectious Diseases Society of America

Use of antibiotics in penetrating craniocerebral injuries -BSAC Working Party (2000), offsite link

The management of neurosurgical patients with postoperative bacterial or aseptic meningitis or external ventricular drain-associated ventriculitis- BSAC Working Party (2000), offsite link

Guideline for the management of the hot swollen joint in adults -BSR, BSAC, et al. (2006) offsite link

Diagnosis and Management of Prosthetic Joint Infection - IDSA (2013) pdf 500 kb ©2013 by the Infectious Diseases Society of America

Surviving Sepsis Campaign: International Guidelines for Management of Severe Sepsis and Septic Shock: 2012 by multiple organizations (offsite link pdf 2.9 mb)

Vancomycin monitoring and dosing (1/09)

Evaluation of fever and infection in long term care facilities ©2009 by the Infectious Diseases Society of America

Guidelines for Preventing Infectious Complications among Hematopoietic Cell Transplantation Recipients: A Global Perspective Amer Soc Blood Marrow Transplantation/IDSA, 2009


Pneumonia & Upper Respiratory Tract

Community Acquired Pneumonia

Hospital and Healthcare-Associated Pneumonia

    CDC Guidelines for the Prevention of Nosocomial Pneumonia (2003 published Mar04) offsite html link or onsite pdf file (811kb)

    ATS/IDSA Guidelines for the Management of Adults with Hospital-Acquired, Ventilator-associated, and Healthcare-associated pneumonia (2004, published 2005)-Offsite ATS link (360Kb, pdf)

    British Society for Antimicrobial Chemotherapy Guidelines for the Management of Hospital-Acquired Pneumonia in the UK (July 2008) offsite link (342 kb, pdf)

Influenza

Upper Respiratory Tract Infections


Tuberculosis

General Primers and Definitions

CDC Core Clinical Curriculum on Tuberculosis - includes information on prophylaxis, diagnosis, antituberculous drugs, epidemiology, and therapy (offsite link, updated periodically)

CDC Self-Study Modules on Tuberculosis (offsite link)

American Thoracic Society /CDC/IDSA Statement on Diagnostic Standards and Classification of Tuberculosis in Adults and Children -1999 (published April 2000, pdf 474 kb)

IUATLD Management of Tuberculosis (Orange Guide) (2010)-offsite link pdf 1 mb

NICE - TB Clinical Diagnosis and Management (UK National Institute for Health and Clinical Excellence (March 2011) - excellent, offsite link

Canadian TB Standards, 7th edition 2013 - superb source for everything about clinical and diagnostic aspects of TB (July 2013) offsite link

 

Treatment Guidelines

American Thoracic Society/CDC/IDSA Statement on the Treatment of Tuberculosis (Oct 2002, pdf 525 kb)

Practice Guidelines for the Treatment of Tuberculosis -IDSA Oct 2000, pdf 70kb; ©2000 by the Infectious Diseases Society of America

WHO Treatment of MDR Tuberculosis - Field Guide, 2010, offsite pdf, 980 kb

Also see the above NICE guidelines

HIV Specific Treatment and Prevention Guidelines

Prevention and Treatment of Tuberculosis Among Patients Infected with Human Immunodeficiency Virus: Principles of Therapy and Revised Recommendations - CDC Recommendation October 1998 (pdf 750 kb) OR offsite link

Appendix to above HIV /TB treatment html document (link to CDC web)

Managing drug interactions in the treatment of HIV-related tuberculosis -CDC recommendations Dec 2007 pdf 228 kb OR offsite link

Diagnosis and Treatment of Latent TB

American Thoracic Society/CDC/IDSA/AAP Statement on Targeted Tuberculin Testing and Treatment of Latent Tuberculosis Infection -1999 (published April 2000, pdf 699 kb) -Also view the warnings on use of rifampin/pza together (Aug 2002, html)

CDC - Treatment of latent TB with INH+rifapentine (published 12/2011, with erratum 2/2012) pdf 485 kb

TB Drug Side-effect and Interactions

ATS-Hepatotoxicity of anti-Tb drugs (offsite pdf, 1.2 mb, 2006)

Managing drug interactions in the treatment of HIV-related tuberculosis -CDC recommendations Dec 2007 pdf 228 kb OR offsite link

Non-Tuberculous Mycobacterial Infections

ATS-IDSA guidelines for the diagnosis and treatment of non-tuberculous mycobacterial infections (offsite link, pdf 930 kb, 2/07) 


WHO, IUATLD Tuberculosis Guidelines, Especially for Low Income Countries

Laboratory Diagnosis and Management

IUATLD Direct Microscopy Guide for the Diagnosis of TB (5th ed, 2000) pdf 707kb

IUATLD Guide for Nat. TB Ref. Labs and National Laboratory Networks (1998) pdf 1.1 mb

Res. Inst. of TB/IUATLD AFB Microscopy Training (2005)-complete document pdf 11.4 mb

Research Inst. of TB/IUATLD AFB Microscopy Training (2005)Part 1 pdf 4mb

Research Inst. of TB/IUATLD AFB Microscopy Training (2005) Part 2 pdf 6mb

Research Inst. of TB/IUATLD AFB Microscopy Training (2005) Part 3 pdf 1.5 mb

Priorities for tuberculosis bacteriology services in low income countries. IUATLD (2007) Offsite link (pdf 5.4 mb)

 

Clinical Manuals

WHO TB and HIV Clinical Manual (2nd ed, 2004) pdf 726 kb

WHO Treatment of Tuberculosis (4th ed, 2010), pdf 908kb

WHO/IAUTLD TB Manual for Medical Students (1999) pdf 1.1 mb

WHO Diagnosis and Treatment of Smear Negative Pulmonary and Extrapulmonary TB in HIV prevalent, resource-constrained regions (2007) pdf 460 kb

IAUTLD Diagnostic Atlas of Intrathoracic TB in Children (2003) pdf 6.2 mb

IUATLD Management of Tuberculosis (Orange Guide) (2010)-offsite link pdf 1 mb

IUATLD - Diagnosis and Treatment of TB in Children (2010) pdf 860 kb

IUATLD - 2nd line drugs for MDR TB treatment: availability and price (2nd ed, 2012) pdf 1.4 mb

IUATLD - Guidelines for the management of MDR TB (2013) offsite pdf 1.4 mb

Links

WHO (World Health Organization)

IUATLD (International Union Against Tuberculosis and Lung Diseases, has other useful manuals for the management of lung diseases)


 Parasitic, Tick-Borne Diseases, Travel Medicine

HUP Malaria Treatment Guidelines

CDC Malaria Treatment and Diagnosis (off site link)

CDC Malaria Treatment Guidelines Only (July 2013 pdf, 38 kb)

WHO Guidelines for the Treatment of Malaria, 2nd edition (2010, pdf 1.3 mb)

Tick borne North American rickettsial diseases - excellent review of epidemiology, treatment and diagnosis - CDC March 2006 (pdf 790 kb)

Tick-borne Diseases of the United States, Clinician's reference guide 2013, CDC (5.8 mb pdf)

CDC Tick-borne diseases (offsite link)

The Clinical Assessment, Treatment, and Prevention
of Lyme Disease, Human Granulocytic Anaplasmosis,
and Babesiosis
- IDSA Oct 2006, pdf 2.8 mb Excellent update of guidelines ©2006 by the Infectious Diseases Society of America

Treatment of Nervous System Lyme Disease - American Academy of Neurology, May 2007 (offsite link, 190 kb pdf)

Guidelines for the Diagnosis of Tickborne Bacterial Infections in Europe (ESCMID, 2004, offsite link)

IDSA Guidelines for the Practice of Travel Medicine (Jan 07, 3.8 Mb, pdf). A very good travel medicine primer. ©2007 by the Infectious Diseases Society of America

US Military Medical Textbooks - great chapters on parasitic and non-parasitic infectious diseases (offsite link)

Global Disease Alert Map - Alerts of current worldwide infectious diseases outbreaks based on public health, news and Promed alerts (July 08, offsite link)


HIV-Related Information

HIV testing methods used at HUP - Nov 2012, onsite html

Antiretroviral treatment of adults with HIV infection, 2012 USA recomendations- Intnl Antiviral Society July 2012, offsite pdf 200kb

Guidelines for the Use of Antiretroviral Agents in HIV-Infected Adults and Adolescents - Feb 2013 USPHS pdf 1.4mb OR go to the offsite html link . These are frequently updated, so check the offsite version if possible.

Link to AIDSinfo US Dept HHS Website  

Prevention and Treatment of Opportunistic Infections in HIV-Infected Adults and Adolescents -2009, CDC, NIH, IDSA. (pdf, 2 mb)

Recommendations for Use of Antiretroviral Drugs in Pregnant HIV-1-Infected Women for Maternal Health and Interventions to Reduce Perinatal HIV Transmission in the United States -2012, NIH (pdf, 4.7 mb), offsite link. These are frequently updated, so check the offsite version if possible

Guidelines for the Use of Antiretroviral Agents in Pediatric HIV Infection -2012, NIH (pdf 7 mb, offsite link)

Prevention and Treatment of Opportunistic Infections in HIV-Exposed and HIV-Infected Children (2009), CDC, NIH, IDSA, PedIDS, AAP (pdf, 1.8 mb)

Managing drug interactions in the treatment of HIV-related tuberculosis -CDC recommendations Dec 2007 pdf 228 kb OR offsite link

CDC guidelines for postexposure prophylaxis for sexual, injection drug and other nonoccupational HIV exposure (Jan 2005, pdf 112kb)

Management of Occupational HIV exposure - UPHS 2013 (offsite link)

Pre-exposure prophylaxis - UPHS 2014 (pdf 792kb)

Guidelines for the evaluation and management of dyslidipemia in HIV-infected adults - IDSA Aug 2003 ©2003 by the Infectious Diseases Society of America

National HIV/AIDS Clinician's Consultation Center

Primary Care Guidelines for the Management of Persons InfectedWith HIV: 2013 Update by the HIV Medicine Association of the Infectious
Diseases Society of America (pdf 333kb, Nov 2013) ©2013 by the Infectious Diseases Society of America

HIV Testing in Health Care Settings- Revised Recommendations - CDC Sept 2006 (pdf 214 kb)


Bioterrorism

CDC Bioterrorism Webpages (link)

Classical Clinical Description of Inhalation Anthrax (Dec 1960 Am J. Med. paper by Plotkin and colleagues)

Consensus Statements on Bioterrorism Agents, published in JAMA (links)

ASM Sentinel Laboratory Agent Summaries and Guidelines (offsite link)

Public health response to biological and chemical weapons: WHO guidance (2004) (offsite link)

UPMC Center for Biosecurity (offsite link)

U.S. Army Medical Dept. Textbooks of Military Medicine (offsite link)

U.S. Army Medical Department Medical Aspects of Biological Warfare( 2007, offsite link)

Powerpoint slides of cutaneous anthrax - much better quality than the CDC ones - from PHLS website (see below) ppt, 98kb.

UK HPA Training Slides on Clinical Aspects of Deliberate Release of Biological Agents - an excellent site with information on several biological agents (2009, offsite link)

IDSA Biodefense Information and Resources (offsite link)

European Guidelines on Bioterrorism ("Bichat" Guidelines)- (offsite link) excellent brief summaries by agent, January 2005

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