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TABLE OF CONTENTS
New PostingsUpdated IDSA guidelines for:(all © by the Infectious Diseases Society of America)
Management of Acute Rhinosinusitis( 3/2012)
Updated CDC/NIH guidelines for:INH + Rifapentine treatment for latent TB 2011 (posted 5/12)
Clinical Microbiology LaboratoryAntimicrobial Susceptibilities at UPHS HUP Antimicrobial Susceptibility Profiles for 2011 Jan-June Presbyterian Medical Center Susceptibility Profiles for 2011 Jan-June Antimicrobial Susceptibility Testing and Interpretation & Drug Resistance Antimicrobial Susceptibility of Rapidly Growing Mycobacteria How to Interpret Susceptibility Results - What "S", "I", and "R" Means and How Testing is Performed Eucast Expert Rules for Antimicrobial Susceptibility Test Interpretation (offsite pdf, 214 kb, 4/08) Eucast Clinical Breakpoints (offsite link) Drug Resistance Mechanisms and Prevalence Problem bacteria at HUP (UPHS only) Gram Stains - Method, Interpretation, and Atlas All About Gram Stains and Gram Staining - Includes a Gram Stain Atlas Specimen Collection Alphabetical guide to laboratory specimen collection for all types of laboratory tests at UPHS (UPHS only) Guide to Specimen Collection for Biowarfare Agents(UPHS only) Mumps testing guidelines from CDC (4/10) Influenza Testing and Results Information (10/10) Blood culture collection (2/11) Problem Sets Teaching lectures (UPHS only) Problem sets (Registered Blackboard users only)HIV Testing HIV antibody testing methods used at HUP Bacterial Taxonomy Deutsche
Sammlung von Mikroorganismen und Zellkulturen Bioterrorism Agents ASM Sentinel Laboratory Guidelines (offsite link) CDC Infectious Diseases Testing CDC infectious diseases laboratory test directory (offsite link) (2/13) CDC specimen submission instructions and electronic submission form (offsite link) (2/13) Respiratory Virus Statistics Influenza for the Current Season
UPHS Guidelines for Infection ControlInfection Control Policies (UPHS Intranet only) Heros Wash Hands (42 mb movie) Stop the Flu (24 mb movie)
UPHS Guidelines for Antimicrobial ProphylaxisGuidelines for Peri-procedure Prophylaxis Antimicrobial Prophylaxis for Prevention of Bacterial Endocarditis(Link to the 2007 AHA Guidelines) Guidelines and Information
Endocarditis and Endovascular Infections Endocarditis Diagnosis and Management AHA Diagnosis and Management of Infectious Endocarditis -1998 (link to AHA web page or link to offsite pdf file 168kb) AHA Infective Endocarditis (2005, offsite link) BSAC Endocarditis Diagnosis and Treatment Guidelines -2012 (PubMed abstract) or off site pdf ( 581 kb) ESCMID, ISC Guidelines on the Prevention, Diagnosis and Treatment of Infective Endocarditis (2009, offsite 17 mb pdf) Clinical Practice Guidelines by the Infectious Diseases Society of America for the Treatment of Methicillin-Resistant Staphylococcus Aureus Infections in Adults and Children (2010,pdf 370 kb) ©2011 by the Infectious Diseases Society of America
Endocarditis Prophylaxis AHA Endocarditis Prophylaxis Guidelines - April 2007 (pdf, 602 kb, off site link) BSAC Endocarditis Prophylaxis Guidelines - 2006 off site pdf (103 kb) Modified Duke Criteria for Endocarditis Nonvalvular Device Infections and Prophylaxis AHA Nonvalvular Cardiovascular Device-Related Infections -2010 (link to offsite AHA pdf file or online version) Guidelines
for the Management of Intravascular Guidelines For The Prevention Of Intravascular Catheter-Related Infections (August 2002; CDC, IDSA, SHEA, et al) (pdf file 340 kb) or link to CDC html file
Introduction to Antifungal Drugs (pdf, 33 kb), ©2000 by the Infectious Diseases Society of America Guidelines for Treatment of Fungal Infections (pdf, 57 kb), ©2000 by the Infectious Diseases Society of America ATS 2011 Treatment of Fungal Infections in Adult Pulmonary and Critical Care Patients (offsite pdf, 367kb, requires subscription until posted on ATS Website) Treatment of Aspergillosis (pdf, 483 kb), ©2008 by the Infectious Diseases Society of America Management of Patients with Blastomycosis (pdf, 265 kb), ©2008 by the Infectious Diseases Society of America Treatment of Candidiasis (pdf, 480 kb), ©2009 by the Infectious Diseases Society of America Treatment of Coccidioidomycosis (pdf, 98 kb), ©2005 by the Infectious Diseases Society of America Management of Cryptococcal Disease (pdf, 461 kb), ©2010 by the Infectious Diseases Society of America Management of Patients with Histoplasmosis (pdf, 172 kb), ©2007 by the Infectious Diseases Society of America Management of Patients with Sporotrichosis (pdf, 120 kb), ©2007 by the Infectious Diseases Society of America Dr. Fungus- A website with extensive information on fungi
Diagnosis and Management of Foodborne Illnesses - CDC RR-4, Apr 2004 (offsite html or onsite pdf 368kb) Practice Guidelines for the Management of Infectious Diarrhea -IDSA Jan 2001 (pdf 284 kb), 2001 by the Infectious Diseases Society of America Treatment Guideance for Clostridium difficile Infections (ESCMID, 2009, offsite pdf) Clinical Practice Guidelines for Clostridium difficile Infections in Adults - 2010 Update (IDSA-SHEA, offsite pdf) Cholera Management for Haitian Outbreak (CDC Dec 2010 pdf 144kb, offsite html)
Diagnosis and Management of Complicated Intra-abdominal Infection in Adults and Children, Surgical Infection Society, IDSA 2010 ( pdf, 732 kb) ©2010 by the Infectious Diseases Society of America Surgical Infection Society Link to Guidelines Updated (2010) ISPD Guidelines for Peritoneal Dialysis Related Infections (3/2011) Chronic Hepatitis B Antiviral Treatment Guidelines Amer Assoc Study Liver Dis Guidelines 2009 (offsite pdf, 500 kb) Chronic Hepatitis C type 1 treatment- Amer Assoc Study Liver Dis Guidelines 2011 (offsite pdf, 420 kb) Diagnosis and treatment of asymptomatic bacteriuria in adults - IDSA, ASN, AGA, March 2005 ©2005 by the Infectious Diseases Society of America pdf 133 kb 2010 International Practice Guidelines for Antimicrobial Treatment of Acute Uncomplicated Cystitis and Pyelonephritis in Women (pdf, 240 kb), ©2011 by the Infectious Diseases Society of America Diagnosis, Prevention, and Treatment of Catheter- Associated Urinary Tract Infection in Adults, 2009, IDSA pdf, (469 kb), ©2010 by the Infectious Diseases Society of America CDC December 2010 Guidelines for the Treatment of Sexually Transmitted Diseases (pdf 1.1mb) See also Hepatitis and HIV sections
Infection Control Guidelines CDC Guidelines for the Prevention of Nosocomial Pneumonia (2003 published Mar04 offsite html link or onsite pdf file (811kb) Guidelines for Preventing Infectious Complications among Hematopoietic Cell Transplantation Recipients: A Global Perspective (ASBMT, IDSA, 2009) pdf file 1.4 mb HICPAC Guidelines for the Prevention of Intravascular Catheter-Related Infections, 2011, pdf 1.0 mb Guidelines for the Prevention of Perinatal Group B Streptococcal Disease (Nov 2010; CDC) pdf file 1.6 MB CDC-HICPA Guidelines for Environmental Infection Control in Health-Care Facilities (June 2003) link to pdf file (1 MB) or html document HICPAC Guideline for Isolation Precautions: Preventing Transmission of Infectious Agents in Healthcare Settings, 2007 (6/07, 1.3 mb pdf) CDC- Prevention of TB Transmission in Health Care Facilities, Dec 2005 (pdf 1.2 mb) Guideline for Hand Hygiene in Healthcare Settings (October 2002; CDC) pdf file 506kb or link to CDC html file Updated Norovirus Outbreak Management and Disease Prevention Guidelines (CDC, 3/11) pdf 850kb CDC guidelines for postexposure prophylaxis for occupational HIV, HBV, and HCV (August 2001, pdf, 343kb) CDC guidelines for occupational HIV postexposure prophylaxis (Sept 2005, pdf ) CDC guidelines for postexposure prophylaxis for sexual, injection drug and other nonoccupational HIV exposure (Jan 2005, pdf 112kb) CDC ACIP guidelines for postexposure hepatitis A prophylaxis (Oct 2007, offsite link) CDC guidelines for postexposure non-occupational hepatitis B prophylaxis (2006, offsite link) CDC guidelines for HBV, HCV, HIV, Tetanus Postexposure prophylaxis after bombing or other mass-casualty event (August 2008, pdf 263kb) Immunization Adult and Pediatric Immunization Guidelines (2002; IDSA) pdf file 670 kb or link to IDSA html file 2002 by the Infectious Diseases Society of America Adult Immunization Schedule 2013, ACIP pdf file 347kb Pertussis Treatment and Postexposure Prophylaxis, CDC, Dec 2005, pdf file 210kb Smallpox vaccination and adverse Reactions (Jan 2003; CDC) link to pdf file (13MB) or html document ACIP-HICPAC Use of Tdap (Tetanus, reduced diphtheria toxoid, acellular pertussis) Vaccine in Adults, Dec 2006 (pdf 412 kb)ACIP Immunization Schedule for Persons 0-18 Years of Age, Jan 2011, (pdf 160 kb) ACIP Immunization of Health Care Personnel, Nov 2011, (pdf 722 kb) Surgical Prophylaxis Antimicrobial Prophylaxis for Surgery IDSA/ASHP/SIS/SHEA Feb 2013 (offsite link pdf 1 mb) Prevention of Infections Associated with Combat Injuries SIS, IDSA August 2011 (offsite pdf link 860 kb) Communicable Disease Reporting Reporting communicable diseases in Philadelphia (external link to Philadelphia Dept. of Public Health Division of Disease Control)
Infectious Diseases Society of America and British Society for Antimicrobial Chemotherapy Guidelines IDSA Guidelines in iPhone and iPad format2010 Guidelines for the Use of Antimicrobial Agents in Neutropenic Patients with Cancer (pdf, 518 kb) or link to IDSA guidelines ©2011 by the Infectious Diseases Society of America Guidelines for evaluation of new fever in critically ill adult
patients: 2008 Amer. Coll. Crit. Care The Clinical Assessment, Treatment, and Prevention of Lyme Disease, Human Granulocytic Anaplasmosis, and Babesiosis - IDSA Oct 2006, pdf 2.8 mb Excellent update of guidelines ©2006 by the Infectious Diseases Society of America Practice Guidelines for Outpatient Parenteral Antimicrobial Therapy (pdf 189 kb, June 2004), ©2004 by the Infectious Diseases Society of America Diagnosis and Treatment of Diabetic Foot Infections (pdf 455 kb, May 2012) ©2012 by the Infectious Diseases Society of America Practice Guidelines for the Management of Bacterial Meningitis (pdf 319kb, Nov 2004) ©2004 by the Infectious Diseases Society of America Practice Guidelines for the Diagnosis and Management of Skin and Soft Tissue Infections (pdf 313 kb, Nov 2005) ©2005 by the Infectious Diseases Society of America Guidelines for the prophylaxis and treatment of methicillin-resistant Staphylococcus aureus ( MRSA) infections in the UK- BSAC Working Party offsite link (230 kb, pdf) (2/06) Clinical Practice Guidelines by the Infectious Diseases Society of America for the Treatment of Methicillin-Resistant Staphylococcus Aureus Infections in Adults and Children (2010,pdf 370 kb) ©2011 by the Infectious Diseases Society of America Use of antibiotics in penetrating craniocerebral injuries -BSAC Working Party (2000), offsite link The management of neurosurgical patients with postoperative bacterial or aseptic meningitis or external ventricular drain-associated ventriculitis- BSAC Working Party (2000), offsite link Guideline for the management of the hot swollen joint in adults -BSR, BSAC, et al. (2006) offsite link Diagnosis and Management of Prosthetic Joint Infection - IDSA (2013) pdf 500 kb ©2013 by the Infectious Diseases Society of America Surviving Sepsis Campaign: International Guidelines for Management of Severe Sepsis and Septic Shock: 2012 by multiple organizations (offsite link pdf 2.9 mb) Vancomycin monitoring and dosing (1/09) Evaluation of fever and infection in long term care facilities ©2009 by the Infectious Diseases Society of America Guidelines for Preventing Infectious Complications among Hematopoietic Cell Transplantation Recipients: A Global Perspective Amer Soc Blood Marrow Transplantation/IDSA, 2009
Community Acquired Pneumonia
Hospital and Healthcare-Associated Pneumonia
Upper Respiratory Tract Infections
General Primers and Definitions CDC Core Clinical Curriculum on Tuberculosis - includes information on prophylaxis, diagnosis, antituberculous drugs, epidemiology, and therapy (offsite link, updated periodically) CDC Self-Study Modules on Tuberculosis (offsite link) IUATLD Management of Tuberculosis (Orange Guide) (2010)-offsite link pdf 1 mb NICE - TB Clinical Diagnosis and Management (UK National Institute for Health and Clinical Excellence (March 2011) - excellent, offsite link
Treatment Guidelines American Thoracic Society/CDC/IDSA Statement on the Treatment of Tuberculosis (Oct 2002, pdf 525 kb) Practice Guidelines for the Treatment of Tuberculosis -IDSA Oct 2000, pdf 70kb; ©2000 by the Infectious Diseases Society of America WHO Treatment of MDR Tuberculosis - Field Guide, 2010, offsite pdf, 980 kb Also see the above NICE guidelines HIV Specific Treatment and Prevention Guidelines Prevention and Treatment of Tuberculosis Among Patients Infected with Human Immunodeficiency Virus: Principles of Therapy and Revised Recommendations - CDC Recommendation October 1998 (pdf 750 kb) OR offsite link Appendix to above HIV /TB treatment html document (link to CDC web) Managing drug interactions in the treatment of HIV-related tuberculosis -CDC recommendations Dec 2007 pdf 228 kb OR offsite link Diagnosis and Treatment of Latent TB American Thoracic Society/CDC/IDSA/AAP Statement on Targeted Tuberculin Testing and Treatment of Latent Tuberculosis Infection -1999 (published April 2000, pdf 699 kb) -Also view the warnings on use of rifampin/pza together (Aug 2002, html) CDC - Treatment of latent TB with INH+rifapentine (published 12/2011, with erratum 2/2012) pdf 485 kb TB Drug Side-effect and Interactions ATS-Hepatotoxicity of anti-Tb drugs (offsite pdf, 1.2 mb, 2006) Managing drug interactions in the treatment of HIV-related tuberculosis -CDC recommendations Dec 2007 pdf 228 kb OR offsite link Non-Tuberculous Mycobacterial Infections ATS-IDSA guidelines for the diagnosis and treatment of non-tuberculous mycobacterial infections (offsite link, pdf 930 kb, 2/07) WHO, IUATLD Tuberculosis Guidelines, Especially for Low Income Countries Laboratory Diagnosis and Management IUATLD Direct Microscopy Guide for the Diagnosis of TB (5th ed, 2000) pdf 707kb IUATLD Guide for Nat. TB Ref. Labs and National Laboratory Networks (1998) pdf 1.1 mb Res. Inst. of TB/IUATLD AFB Microscopy Training (2005)-complete document pdf 11.4 mb Research Inst. of TB/IUATLD AFB Microscopy Training (2005)Part 1 pdf 4mb Research Inst. of TB/IUATLD AFB Microscopy Training (2005) Part 2 pdf 6mb Research Inst. of TB/IUATLD AFB Microscopy Training (2005) Part 3 pdf 1.5 mb Priorities for tuberculosis bacteriology services in low income countries. IUATLD (2007) Offsite link (pdf 5.4 mb)
Clinical Manuals WHO TB and HIV Clinical Manual (2nd ed, 2004) pdf 726 kb WHO Treatment of Tuberculosis (4th ed, 2010), pdf 908kb WHO/IAUTLD TB Manual for Medical Students (1999) pdf 1.1 mb WHO Diagnosis and Treatment of Smear Negative Pulmonary and Extrapulmonary TB in HIV prevalent, resource-constrained regions (2007) pdf 460 kb IAUTLD Diagnostic Atlas of Intrathoracic TB in Children (2003) pdf 6.2 mb IUATLD Management of Tuberculosis (Orange Guide) (2010)-offsite link pdf 1 mb IUATLD - Diagnosis and Treatment of TB in Children (2010) pdf 860 kb IUATLD - 2nd line drugs for MDR TB treatment: availability and price (2nd ed, 2012) pdf 1.4 mb IUATLD - Guidelines for the management of MDR TB (2013) offsite pdf 1.4 mb Links WHO (World Health Organization) IUATLD (International Union Against Tuberculosis and Lung Diseases, has other useful manuals for the management of lung diseases)
HUP Malaria Treatment Guidelines CDC Malaria Treatment and Diagnosis (2012) (off site link) CDC Malaria Treatment Guidelines Only (Sept 2011 pdf, 38 kb) WHO Guidelines for the Treatment of Malaria, 2nd edition (2010, pdf 1.3 mb) Tick borne North American rickettsial diseases - excellent review of epidemiology, treatment and diagnosis - CDC March 2006 (pdf 790 kb) The Clinical Assessment, Treatment, and Prevention Treatment of Nervous System Lyme Disease - American Academy of Neurology, May 2007 (offsite link, 190 kb pdf) Guidelines for the Diagnosis of Tickborne Bacterial Infections in Europe (ESCMID, 2004, offsite link) IDSA Guidelines for the Practice of Travel Medicine (Jan 07, 3.8 Mb, pdf). A very good travel medicine primer. ©2007 by the Infectious Diseases Society of America US Military Medical Textbooks - great chapters on parasitic and non-parasitic infectious diseases (offsite link) Global Disease Alert Map - Alerts of current worldwide infectious diseases outbreaks based on public health, news and Promed alerts (July 08, offsite link)
HIV testing methods used at HUP - Nov 2012, onsite html Antiretroviral treatment of adults with HIV infection, 2012 USA recomendations- Intnl Antiviral Society July 2012, offsite pdf 200kb Guidelines for the Use of Antiretroviral Agents in HIV-Infected Adults and Adolescents - Feb 2013 USPHS pdf 1.4mb OR go to the offsite html link . These are frequently updated, so check the offsite version if possible. Link to AIDSinfo US Dept HHS Website Prevention and Treatment of Opportunistic Infections in HIV-Infected Adults and Adolescents -2009, CDC, NIH, IDSA. (pdf, 2 mb) Recommendations for Use of Antiretroviral Drugs in Pregnant HIV-1-Infected Women for Maternal Health and Interventions to Reduce Perinatal HIV Transmission in the United States -2012, NIH (pdf, 4.7 mb), offsite link. These are frequently updated, so check the offsite version if possible Guidelines for the Use of Antiretroviral Agents in Pediatric HIV Infection -2012, NIH (pdf 7 mb, offsite link) Prevention and Treatment of Opportunistic Infections in HIV-Exposed and HIV-Infected Children (2009), CDC, NIH, IDSA, PedIDS, AAP (pdf, 1.8 mb) Managing drug interactions in the treatment of HIV-related tuberculosis -CDC recommendations Dec 2007 pdf 228 kb OR offsite link CDC guidelines for postexposure prophylaxis for sexual, injection drug and other nonoccupational HIV exposure (Jan 2005, pdf 112kb) Management of Occupational HIV exposure - CDC Sept 2005 Guidelines for the evaluation and management of dyslidipemia in HIV-infected adults - IDSA Aug 2003 ©2003 by the Infectious Diseases Society of America National HIV/AIDS Clinician's Consultation Center Primary Care Guidelines for the Management of Persons Infected with Human Immunodeficiency Virus IDSA (pdf 4622kb, Sept 2009) ©2009 by the Infectious Diseases Society of America HIV Testing in Health Care Settings- Revised Recommendations - CDC Sept 2006 (pdf 214 kb) BioterrorismCDC Bioterrorism Webpages (link) Classical Clinical Description of Inhalation Anthrax (Dec 1960 Am J. Med. paper by Plotkin and colleagues) Consensus Statements on Bioterrorism Agents, published in JAMA (links) ASM Sentinel Laboratory Agent Summaries and Guidelines (offsite link) Public health response to biological and chemical weapons: WHO guidance (2004) (offsite link) UPMC Center for Biosecurity (offsite link) U.S. Army Medical Dept. Textbooks of Military Medicine (offsite link) U.S. Army Medical Department Medical Aspects of Biological Warfare( 2007, offsite link) Powerpoint slides of cutaneous anthrax - much better quality than the CDC ones - from PHLS website (see below) ppt, 98kb. UK HPA Training Slides on Clinical Aspects of Deliberate Release of Biological Agents - an excellent site with information on several biological agents (2009, offsite link) IDSA Biodefense Information and Resources (offsite link) European Guidelines on Bioterrorism ("Bichat" Guidelines)- (offsite link) excellent brief summaries by agent, January 2005 |
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