Director, Electrophysiology Laboratory
Professor of Medicine

E-Mail

Hospital of The University of Pennsylvania
Department of Medicine
Cardiovascular Medicine Division
9129 Founders Pavilion
3400 Spruce Street
Philadelphia, PA 19104

Appointments

Clinical Specialty:

• Cardiovascular Medicine
• Cardiac Electrophysiology

Practice Location:

• Hospital of The University of Pennsylvania, Ground Rhoads

Education:

• MD: Johns Hopkins School of Medicine, Baltimore, MD
• Residency: Hospital of the University of Pennsylvania
• Fellowship: Hospital of the University of Pennsylvania
• Postdoctoral Fellowship: Hospital of the University of Pennsylvania

Research Interest:

• Catheter Ablation of Atrial Fibrillation
• Physiology and Substrate of Ventricular Tachycardia

Selected Publications:

1. Callans DJ, Kieval RS, Hook BG, Moore EN, Spear JF: The effect of coronary perfusion of potassium or heptanol on conduction and ventricular arrhythmias. Am. J. Physiol. 1992; 263 (Heart Circ. Physiol. 32): H1382-H1389
2. Callans DJ, Hook BG, Josephson ME: Comparison of resetting and entrainment of uniform sustained ventricular tachycardia: further insights into the characteristics of the excitable gap. Circulation 1993;87:1229-1238
3. Callans DJ, Zardini M, Gottlieb CD, Josephson ME: The relative contribution of functional versus anatomic barriers in human ventricular tachycardia: An analysis with resetting from two sites. J Am Coll Cardiol 1996;27:1106-1111
4. Callans DJ, Menz V, Schwartzman DS, Gottlieb CD, Marchlinski FE: Repetitive monomorphic ventricular tachycardia from the left ventricular outflow tract: Electrocardiographic patterns consistent with a left ventricular site of origin. J Am Coll Cardiol 1997;29:1023-1027
5. Callans DJ, Ren J-F, Michele J, Marchlinski FE, Dillon SM: Electroanatomic left ventricular mapping in the porcine model of healed anterior myocardial infarction: Correlation with intracardiac echocardiography and pathological analysis. Circulation 1999;100:1744-1750
6. Marchlinski FE, Callans DJ, Gottlieb CD, Zado E: Linear ablation lesions for control of unmappable ventricular tachycardia in patients with ischemic and nonischemic cardiomyopathy. Circulation 2000;101:1288-1296
7. Hsia HH, Callans DJ, Marchlinski FE: Characterization of endocardial electrophysiologic substrate in patients with nonischemic cardiomyopathy and monomorphic ventricular tachycardia. Circulation 2003;108:704-710
8. Callans DJ, Gerstenfeld EP, Dixit S, Zado E, Vanderhoff M, Ren J-F, Marchlinski FE. Efficacy of repeat pulmonary vein isolation procedures in patients with recurrent atrial fibrillation. J Cardiovasc Electrophysiol 2004;15:1050-1055
9. Jacobson JT, Afonso VX, Eisenman G, Schultz JR, Lazar S, Michele JJ, Josephson ME, Callans DJ: Characterization of the infarct substrate and ventricular tachycardia circuits with noncontact unipolar mapping in a porcine model of myocardial infarction. Heart Rhythm 2006;3:189-197