Associate Director, Noninvasive Imaging
Professor of Medicine

E-Mail

Hospital of the University of Pennsylvania
Department of Medicine
Cardiovascular Medicine Division
9014 E. Gates Pavilion
Philadelphia, PA 19104-4283

Appointments
Contact: Devonne Love-Moore (215) 662-2912

Clinical Specialty:

• Cardiovascular Medicine

Practice Location:

• Hospital of The University of Pennsylvania, Gates Pavilion

Education:

• MD: University of Pennsylvania School of Medicine
• Residency: Hospital of The University of Pennsylvania
• Fellowship: Hospital of The University of Pennsylvania

Research Interest:

• Ventricular Function
• Cardiac MRI
• Echocardiography
• Ventricular Remodeling
• Pulmonary Hypertension
• Small Animal Cardiac Imaging

Selected Publications:

1. Ferrari VA, Scott CH, Holland GA, Axel L, St. John Sutton M: Ultrafast three-dimensional contrast-enhanced magnetic resonance angiography and imaging in the diagnosis of partial anomalous pulmonary venous drainage. Journal of the American College of Cardiology March 15, 2001;37(4):1120-1128.
2. Zhou R, Pickup S, Scott CS, Glickson JD, Ferrari VA. Assessment of global and regional myocardial function in the mouse using cine- and tagged MRI. Magnetic Resonance in Medicine 2003;49(4):760-764.
3. Kook H, Lepore J, Gitler AD, Lu MM, Ytung WW, Mackay J, Zhou R, Ferrari V, Gruber P, Epstein JA.  Cardiac hypertrophy and histone deacetylase-dependent transcriptional repression mediated by the atypical homeodomain protein Hop. Journal of Clinical Investigation 2003;112:863-871.
4. Pilla J, Blom AS, Brockman DJ, Yuan Q, Ferrari VA, Acker MA.  Mechanical constraint improves myocardial function in a model of heart failure secondary to acute infarction. J Thoracic and Cardiovascular Surgery 2003;126(5):1467-76.
5. Thomas D, Ferrari VA, Janik M, Kim, DH, Pickup S, Glickson JD, Zhou R. Quantitative assessment of regional myocardial function in a rat model of myocardial infarction using tagged MRI. MAGMA 2004;17:179-187
6. Gruber P, Li Z, Li H, Worrad D, Huang B, Abdullah I, Wang W, El-Deiry W, Ferrari VA, Zhou R. In vivo imaging of MLC2v-luciferase, a cardiac-specific reporter gene expression in mice. Academic Radiology 2004;11:1022-8.
7. Kostetskii I, Li J, Xiong Y, Zhou R, Ferrari VA, Patel VV, Molkentin JD, Radice GL. Induced deletion of the N-cadherin gene in the heart leads to dissolution of the intercalated disc structure. Circulation Research 2005;96:346-54.
8. Ismat FA, Zhang M, Kook H, Huang B, Zhou R, Ferrari VA, Epstein JA, Patel VV. Homeobox protein Hop functions in the adult cardiac conduction system. Circulation Research 2005;96:898-903
9. Zhou R, Thomas DH, Qiao H, Bal HS, Choi SR, Alavi A, Ferrari VA, Kung HF, Acton PD. In vivo detection of stem cells grafted in infarcted rat myocardium. Journal of Nuclear Medicine 2005;46:816-822.
10. Thomas D, Dumont C, Pickup S, Misselwitz B, Zhou R, Horowitz J, Ferrari VA. T1-weighted cine FLASH is superior to IR imaging of post-infarction myocardial viability at 4.7T. Journal of Cardiovascular Magnetic Resonance 2006;8(2): 345-352.
11. Wilensky RL, Song HK, Ferrari VA. Role of magnetic resonance and intravascular magnetic resonance in the detection of vulnerable plaques. Journal of the American College of Cardiology 2006;47(8 Suppl):C48-56.
12. Zhou R, Acton PD, Ferrari VA. Imaging stem cells implanted in infarcted myocardium. Journal of the American College of Cardiology 2006;48:2094-2106.
13. Tandri H, Castillo E, Ferrari VA, Nasir K, Dalal D, Bomma C, Calkins H, Bluemke DA. MR imaging of arrhythmogenic right ventricular dysplasia: Sensitivity, specificity, and observer variability of fat detection vs. functional analysis of the right ventricle. Journal of the American College of Cardiology 2006;48:2277-2284.
14. Trivedi CM, Luo Y, Yin Z, Zhang M, Zhu W, Wang T, Floss T,  Goettlicher M, Noppinger PR, Wurst W, Ferrari VA, Abrams CA,  Gruber PJ, Epstein JA. Hdac2 regulates the cardiac hypertrophic response by modulating Gsk3β activity. Nature Medicine 2007;13:324-331.
15. Thomas D, Bal H, Horowitz J, Araujo L, Acton P, Ferrari VA. Noninvasive assessment of myocardial viability in a small animal model of myocardial infarction: Comparison of MRI, SPECT, and PET. Magnetic Resonance in Medicine 2008;59:252-259.