Professor of Medicine, Pharmacology, and Pathology and Laboratory Medicine
Edward S. Cooper, M.D./Norman Roosevelt and Elizabeth Meriwether McLure Professor
Director, Preventive Cardiovascular Medicine and Lipid Clinic
Director, General Clinical Research Center
Associate Director, Institute for Translational Medicine and Therapeutics
Director, Cardiovascular Metabolism Unit, Institute for Diabetes, Obesity, and Metabolism

Primary addresss and contact information:

University of Pennsylvania School of Medicine
654 BRBII/III
421 Cure Blvd
Philadelphia, PA 19104
Tel: 215-573-4176 | Fax: 215-573-8606

E-Mail

Assistant: Linda Watts 215-573-4176
lindaw@mail.med.upenn.edu

Clinical practice location and contact information (for patients):

Penn Heart and Vascular Center
Perelman Center for Advanced Medicine
East Pavilion, 2nd Floor
3400 Civic Center Boulevard
Philadelphia, PA 19104

Appointments
Contact: Kathleen Paziora (215) 615-4949

Clinical Specialty:

• Preventive Cardiovascular Medicine and Lipid Disorders

Education:

• MD: Medical College of Pennsylvania, Philadelphia, PA
• Residency: Yale-New Haven Hospital, New Haven, CT
• Fellowship: National Heart, Lung, and Blood Institute, NIH, Bethesda, MD

Research Interest:

• Molecular regulation of lipid metabolism and atherosclerosis
• Molecular regulation of HDL metabolism and reverse cholesterol transport
• Mechanisms of atheroprotection by HDL
• Non-invasive imaging of atherosclerosis
• Novel risk factors and biomarkers for atherosclerotic vascular disease
• Novel therapies for lipid disorders, to raise HDL, and to reverse heart disease

Selected Publications:

1. Rader DJ. Inflammatory markers of coronary risk. New Engl J Med 343:1179-1182; 2000.
2. Rader DJ. A new feature on the cholesterol-lowering landscape. Nature Med 7:1282-1284; 2001.
3. Rader DJ. High-density lipoproteins as an emerging therapeutic target for atherosclerosis. JAMA 2003:290(17):2292-300.
4. Brousseau ME, Schaefer EJ, Wolfe ML, Bloedon LT, Digenio AG, Clark RW, Mancuso JP, Rader DJ. Effects of an inhibitor of cholesteryl ester transfer protein on HDL cholesterol. N Engl J Med 2004;350(15):1505-15.
5. Rader DJ, Pure E. Lipoproteins, macrophage function, and atherosclerosis: Beyond the foam cell? Cell Metabolism 2005 1: 223-230.