Amanda Christini, MD
Director, Strategic Initiative, Penn Medicine Center for Health Care Innovation
Assistant Professor of Clinical Medicine, University of Pennsylvania Perelman School of Medicine

Amanda brings to the Center her background in biotechnology business development, partnership negotiation and management, operations, program management, M&A and clinical development of novel therapeutics. Prior to her medical training, she was Head of the Vaccines and Immunotherapeutics Business Unit and Director of Business Development at Maxygen, a San Francisco Bay Area based biotechnology spin-out focusing on applying molecular evolution as a novel approach to target identification in multiple therapeutic areas and industries. She was responsible for negotiating and subsequently managing successful collaborations with multiple pharmaceutical companies, foundations, universities and government agencies, as well as managing the company’s preclinical programs and facilitating their progression into clinical trials. Before joining Maxygen she was Director of Business Development at Valentis, a gene therapy company developing non-viral, gene-based therapeutics for various indications. At Valentis she identified acquisition targets, led an M&A integration, negotiated multiple partnerships and participated in the management of product candidates from preclinical through early-stage clinical trials. Prior to Valentis she managed biotechnology intellectual property as a licensing associate at the Massachusetts Institute of Technology.

Amanda is a co-founder of Ventrigen, a clinical-stage biotechnology start-up company focused on the development of native GLP-1 for the treatment of advanced heart failure, and serves as an advisor to several area start-up companies in health care IT and diagnostics.

Her 15 yrs of experience in the biotechnology industry gives Amanda a unique perspective on the challenges facing the financing, development and acceptance of new therapeutics and diagnostics at the level of physicians, patients, institutions and payers.

Amanda got her BS at Tufts University and her MD at the University of Pittsburgh School of Medicine. She completed her residency training in Internal Medicine at the Hospital of the University of Pennsylvania. She is a member of the Alpha Omega Alpha medical honor society and the American College of Physicians.

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