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Research

Faculty and staff at CEP are actively engaged in research in the areas of comparative effectiveness, health technology assessment, evidence-based medicine, guideline development, and computerized clinical decision support. For more information about the research interests of individual faculty and staff, please click on their name in "Contact Us."

Selected guidelines are posted to the National Guideline Clearinghouse. Selected evidence reviews and advisories are posted to the Health Technology Assessment Database of the Centre for Reviews and Dissemination, which is also indexed by the Cochrane Library. Selected publications and presentations are posted below.

Publications

57. Bartsch SM, Umscheid CA, Fishman N, Lee BY.  Reply to authors.  Clin Infect Dis. 2013. (In press)

56. Williams K, Mitchell M.  Inpatient alcohol withdrawal: time to prevent the preventable?  Journal of General Internal Medicine. 2013. (In press).

55. Baillie CA, VanZandbergen C, Tait G, Hanish A, Leas B, French BC, Hanson CW, Behta M, Umscheid CA. The readmission risk flag: using the electronic health record to automatically identify patients at risk for 30 day readmission. Journal of Hospital Medicine. 2013; 8(12): 689-695.

54. Richardson K, Schoen M, French BC, Umscheid CA, Mitchell MD, Arnold SE, Heidenreich PA, Rader DJ, deGoma EM. Statins and cognitive function: a systematic review. Annals of Internal Medicine. 2013;159(10): 688-698.

53. Prom R, Umscheid CA, Kasbekar N, Spinler SA. Simvastatin amiodarone drug interaction alert: adherence to dosing recommendations before and after the implementation of a revised computerized provider order entry drug interaction alert. American Journal of Health System Pharmacy.  2013; 70: 1878-1879.

52. Mitchell MD. The Costs & Benefits of Radial Catheterization. Physician’s Weekly.  Available at: http://www.physiciansweekly.com/radial-catheterization-costs-benefits/.  Accessed August 16, 2013.

51. Baillie CA, Goren EN, Jacob J, Patel N, Umscheid CA, Xu KT. In the literature: hospital medicine related research you need to know. The Hospitalist. February 2013.

50. Seem DL, Lee I, Umscheid CA, Kuehnert MJ.  Excerpt from "Public health service guideline for reducing human immunodeficiency virus, hepatitis B virus, and hepatitis C virus during organ transplantation."  American Journal of Transplantation. 201313(8): 1953-62.

49. Petrosino A, Turpin-Petrosino C, Hollis-Peel ME, Lavenberg JG. 'Scared Straight' and other juvenile awareness programs for preventing juvenile delinquency. Cochrane Database of Systematic Reviews.  2013; Issue 3. Art. No.: CD002796. DOI: 10.1002/14651858.CD002796.pub2.

48. Bartsch SM, Umscheid CA, Fishman NO, Lee BY. Is fidaxomicin worth the cost? An economic analysis. Clinical Infectious Diseases. 2013; 57(4): 555-561.

47. Seem DL, Lee I, Umscheid CA, Kuehnert MJ. Public health service guideline for reducing human immunodeficiency virus, hepatitis B virus, and hepatitis C virus during organ transplantation.   Public Health Reports.  2013;128: 247-343.

46. Umscheid CA. A primer on performing systematic reviews and meta-analyses.  Clinical Infectious Diseases. 2013; 57(5): 725-34.

45. Barbieri J, Fuchs B, Fishman N, Cutilli C, Umscheid CA, Kean C, Koshy S, Sullivan P, Brennan PJ, Kelz R.  The mortality review committee: a novel and scalable approach to reducing inpatient mortality.  Joint Commission Journal on Quality and Patient Safety. 2013;39(9): 387-395.

44. Mudireddy PR, Agarwal R, Williams K.  The role of albumin in the management of hepatorenal syndrome: a systematic review. Journal of Clinical Outcomes Management. 2013; 20(6):264-270.

43. Agarwal R, Gosain P, Kirkpatrick JN, Alyousef T, Doukky R, Singh G, Umscheid CA.  Tissue doppler imaging for diagnosis of coronary artery disease: a systematic review and meta-analysis.  Cardiovascular Ultrasound. 2012, 10:47.

42. Umscheid CA. Snapshots of low value medical care.   JAMA: Internal Medicine. 2013; 173(3):186-187. 

41. Umscheid CA, Hanish A, Chittams J, Weiner M, Hecht TEH. Effectiveness of a novel and scalable clinical decision support intervention to improve venous thromboembolism prophylaxis: a quasi-experimental study. BMC Medical Informatics and Decision Making.  2012,12: 92.

40. Gauer R, Qiu KM. Clinical Inquiry: Does blood pressure screening benefit children?  The Journal of Family Practice. 2012; 61(7): 425-426.

39. Mitchell MD, Agarwal R, Hecht T, Umscheid CA. Non-pharmacologic interventions for prevention of catheter-related thrombosis: a systematic review. Journal of Critical Care. 2013; 28(3): 316-324.

38. Mitchell MD, Hong JA, Lee BY, Umscheid CA, Bartsch SM, Don CW.  Cost savings of radial artery access for coronary angiography and intervention. Circulation: Cardiovascular Quality and Outcomes. 2012;5(4):454-462.

37. Mitchell MD, Gehrman P, Perlis M, Umscheid CA. Comparative effectiveness of cognitive behavioral therapy for insomnia: a systematic review.  BMC Family Practice. 2012, 13:40.

36. Smetana GW, Umscheid CA, Chang S, Matchar DB. Methods guide for authors of systematic reviews of medical tests: a collaboration between the Agency for Healthcare Research and Quality and the Journal of General Internal Medicine. Journal of General Internal Medicine. 2012; 27(Suppl 1):S1-3.

35. Agarwal R, Saini A, Alyousef T, Umscheid CA. Magnetocardiography for the diagnosis of coronary artery disease: a systematic review and meta-analysis. Annals of Noninvasive Electrocardiology. 2012; 17(4):291-298.

34. Katz EB, Carrier ER, Umscheid CA, Pines JM.  Comparative effectiveness of care coordination interventions in the emergency department: a systematic review. Annals of Emergency Medicine.2012; 60(1):12-23.

33. Mitchell MD, Williams K, Kuntz G, Umscheid CA.  When the decision is what to decide: using evidence inventory reports to focus health technology assessments.  International Journal of Technology Assessment in Health Care. 27(2): 127-32. 2011.

32. Umscheid CA, Hanson CW. A follow-up report card on computer-assisted diagnosis – the grade: C+. Journal of General Internal Medicine. 2012;27(2):142-4.

31. MacCannell T, Umscheid CA, Agarwal RK, Lee I, Kuntz G, Stevenson, KB, and the Healthcare Infection Control Practices Advisory Committee. Guideline for the prevention and control of norovirus gastroenteritis outbreaks in healthcare settings. Infection Control and Hospital Epidemiology. 2011; 32(10): 939-969.

30. Leonard CE, Freeman CP, MaCurdy T, Umscheid CA, López de Nava K, Molina T, MaCurdy S, Kang-Yi CD, Razzaghi H, Hsia D.  Prevalence and Medicare reimbursement by recurrent International Classification of Diseases categories,2006-2009. Utilization and Costs. Data Points #5. Available at: http://www.effectivehealthcare.ahrq.gov/ehc/products/316/703/DataPoints5.pdf Accessed July 18, 2011.

29. Umscheid CA, Margolis DJ, Grossman CE. Key concepts of clinical trials: a narrative review.  Postgraduate Medicine. 2011; 123(5): 194-204.

28. Umscheid CA. The potential for increasing quality and reducing costs.  Annals of Internal Medicine. 2011; 155(8):563-562.

27. Baille C, Umscheid CA. In the literature: hospital medicine related research you need to know. The Hospitalist June 2011.

26. Lee I, Fishman NO, Agarwal RK, Lee BY, Umscheid CA. Reply to Maiwald et al and Riccio et al. Infection Control and Hospital Epidemiology. 2011; 32(4): 406-8.

25. Umscheid CA, Mitchell MD, Doshi JA. Response to Graves et al. Infection Control and Hospital Epidemiology. 2011. (Letter in press).

24. Lee BY, McGlone SM, Bailey RR, Umscheid CA, Muder RR. Economic impact of norovirus outbreaks in hospitals. Infection Control and Hospital Epidemiology. 2011; 32(2): 191-93.

23. Lee BY, Wettstein ZS, McGlone SM, Bailey RR, Umscheid CA, Smith KJ, Muder RR. Economic value of norovirus outbreak control measures in healthcare settings. Clinical Microbiology and Infection. 2011  April; 27(2):127-32.

22. Umscheid CA, Mitchell MD, Doshi JA, Agarwal R, Williams K, Brennan PJ. Estimating the proportion of healthcare-associated  infections that are reasonably preventable  and the related mortality and costs. Infection Control and Hospital Epidemiology. 2011 February; 32(2): 101-14.

21. Umscheid CA, Williams K, Brennan PJ. Hospital-based comparative effectiveness centers: translating research into practice to improve the quality, safety and value of patient care. Journal of General Internal Medicine. 2010 December; 25(12): 1352-5.

20. Umscheid CA. Maximizing the clinical utility of comparative effectiveness research. Clinical Pharmacology and Therapeutics. 2010 December: 88(6): 876-9.

19. Lee I, Agarwal RK, Lee BY, Fishman NO, Umscheid CA. A systematic review and cost analysis  comparing use of chlorhexidine with use of iodine for preoperative skin   antisepsis  to preventsurgical site infection. Infection Control and Hospital Epidemiology. 2010 December; 31(12): 1219-29.

18. Agarwal R, Hecht TE, Lazo MC, Umscheid CA. Venous thromboembolism prophylaxis for patients undergoing bariatric surgery: a systematic review. Surgery for Obesity and Related Diseases. 2010; March ; 6(2): 213-20.

17. Umscheid CA. The value of comparative effectiveness reviews is locally based. KevinMD.com Web site. Available at: http://www.kevinmd.com. Accessed July 20, 2010.

16. Umscheid CA. Health care's "Consumer Reports": helping doctors find the best treatments for you. The Huffington Post. Available at: http://www.huffingtonpost.com. Accessed July 13, 2010.

15. Mitchell MD, Williams K, Brennan PJ, Umscheid CA. Integrating local data into hospital-based healthcare technology assessment: two case studies. International Journal of Technology Assessment in Health Care. 2010; 26(3):294-300.

14. Mitchell MD*, Mikkelsen ME*, Umscheid CA, Lee I, Fuchs BD, Halpern SD. A systematic review to inform institutional decisions about the use of extracorporeal membrane oxygenation during the H1N1 influenza pandemic. Critical Care Medicine. June 2010; 38(6): 1398-1404. Notes. (*First Authors)

13. Umscheid CA, Agarwal RK, Brennan PJ, and the Healthcare Infection Control Practices Advisory Committee. Updating the guideline development methodology of the Healthcare Infection Control Practices Advisory Committee. American Journal of Infection Control. May 2010; 38(4): 264-73.

12. Gould CV, Umscheid CA, Agarwal RK, Kuntz G, Pegues DA, and the Healthcare Infection Control Practices Advisory Committee (HICPAC). Guideline for the prevention of catheter-associated urinary tract infections. Infection Control and Hospital Epidemiology. April 2010; 31(4): 319-326.

11. Baillie C, Marandola E, Ocampo J, Umscheid CA. In the literature: the latest hospital medicine related research you need to know. The Hospitalist. March 10 2010.

10. Agarwal R, Williams K, Umscheid CA, Welch WC. Osteoinductive bone graft substitutes for lumbar fusion - a systematic review. Journal of Neurosurgery. Dec 2009; Spine 11(6): 729-40.

9. Mitchell MD, Anderson B, Williams K, Umscheid CA. Systematic review of heparin flushing and other interventions to maintain patency of central venous access devices. Journal of Advanced Nursing. October 2009; 65(10): 2007-2021.

8. Anderson BJ, Mitchell MD, Williams K, Umscheid CA. Maintenance of central venous catheters: an evidence-based approach. Nursing Times. Feb 2009; 106(6): 15-16.

7. Umscheid CA. Should guidelines incorporate evidence on patient preferences? Journal of General Internal Medicine. 2009; 24: 988-90. Notes. (Editorial)

6. Crites GE, McNamara MC, Akl EA, Richardson WS, Umscheid CA, Nishikawa J. Evidence in the learning organization. BMC Health Research Policy and Systems. 2009; 7(4). Notes. doi:10.1186/1478-4505-7-4 (This article has been designated as "Highly accessed" by the publisher based on the number of times it's been accessed relative to its age and the journal in which it is published.).

5. Agarwal R, Brunelli SM, Umscheid CA. Reply to "Which laboratory parameters are characteristic for nephrogenic systemic fibrosis?" Nephrology Dialysis Transplantation. 2009; 24(7): 2293-2294. Notes. (Letter)

4. Agarwal R, Brunelli SM, Williams K, Mitchell MD, Feldman HI, Umscheid CA.: Gadolinium-based contrast agents and nephrogenic systemic fibrosis: a systematic review and meta-analysis. Nephrology Dialysis Transplantation. 2009; 24: 856-863.

3. Mitchell MD. Technology assessment is performed by payers, too. Radiology. Mar 2008; 246(3):984-5. Notes. (Letter)

2. Umscheid CA, Kohl BA, Williams K. Antifibrinolytic use in adult cardiac surgery. Current Opinion in Hematology. 2007; 14: 455-467. Notes. (Review)

1. Umscheid CA, Agarwal R, Gibson G. Weight-based low-molecular-weight heparin versus weight-based intravenous unfractionated heparin. Ann Intern Med. Sep 2007; 147(6): 433-434. Notes. (Letter)

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Presentations

Betesh J, VanZandbergen C, Fuchs BD, Tait G, Hanish A, Fishman N, French BC, Umscheid CA.  The Impact of an Automated Early Warning System for Sepsis.  Podium presentation at the American Medical Informatics Association Annual Meeting in Washington, DC, November 2013.

Mitchell MD, Leas B, Lavenberg JL, Williams K, Umscheid CA.  Integrating Guidelines into Local Clinical Practice and Policy Using Hospital-based HTA.  Podium presentation at the Guidelines International Network Annual Meeting in San Francisco, CA, August 2013.

Mitchell MD, Leas B, Lavenberg JL, Goldmann DR, Umscheid CA.  A Simple Guideline Appraisal Instrument Based On IOM Standards.  Poster presentation at the Guidelines International Network Annual Meeting in San Francisco, CA, August 2013.

Leas BL, Mitchell MD, Lavenberg JG, Williams K, Umscheid CA.  The Value of a Hospital-Based Comparative Effectiveness Research Center.  Poster presentation at the AcademyHealth Annual Research Meeting in Baltimore, MD, June 2013

Lavenberg JG.  Decision Making within a Health System: CEP and the Role of Information Retrieval. Podium presentation at the Medical Library Association Annual Meeting in Boston, MA. May 2013.

Mitchell MD, Leas B, Lavenberg JL, Williams K, Umscheid CA.  A Hospital-focused Evidence-based Practice Center Creates and Adapts Clinical Guidelines for Local and National Use.  Poster presentation at “Evidence-Based Guidelines Affecting Policy, Practice and Stakeholders (E-GAPPS)” Conference in NY, NY, December 2012.

Lavenberg JG, Mitchell MD, Leas B, Williams K, Umscheid CA. Evidence-based QI: The first six years of a hospital-based HTA center. Podium presentation at the 2012 Summer Institutes on Evidence-Based Quality Improvement Conference in San Antonio, Texas.

Betesh, J, Mitchell, MD, Umscheid CA: An Evidence Based Practice Center in an Academic Medical Center Supports Continuing Quality Improvement,. Poster  presentation at the 2012 IHI National Forum in Orlando, Florida, December 2012.

Mitchell MD, Williams K, Umscheid CA: A US Hospital-based Health Technology Assessment Center to Improve the Quality, Safety and Cost-effectiveness of Patient Care.  Poster presentation at Cochrane Colloquium XIX, Madrid, 2011.

Mitchell MD, Hong JA, Umscheid CA, Don CW.: Cost Savings of Radial Artery Access for Coronary Angiography and Intervention. Poster Presentation at Quality of Care and Outcomes Research in Cardiovascular Disease and Stroke 2011 Scientific Sessions, Washington, DC. Poster presentation at University of Pennsylvania Department of Medicine Research Day, Philadelphia, PA. 2011.

Williams K, Gutsche J, Tan-Torres S, Lazo M, Umscheid CA, DiMartino J. : Challenges in RBC Blood Transfusion in an Academic Medical Center. Oral presentation at the 4th Annual Healthcare Informatics Symposium, Philadelphia, PA. 2011.

Goldmann DR, Umscheid CA, Gabriel P, Weiner M, Day S, Hanish A, Chittams J, Kinosian B.: The Effect of Electronic Medical Record Alerts on Processes of Care Related to Preventing Falls in Community-Dwelling Elderly Patients. Poster presentation at SGIM Annual Meeting, Phoenix, Arizona. Poster presentation at University of Pennsylvania Department of Medicine Research Day, Philadelphia, PA. 2011. 

Mitchell MD, Williams K, Kuntz G, Umscheid CA.  When the decision is what to decide: using evidence inventory reports to focus health technology assessments.  Poster presentation at the 2010 Society of Medical Decision Making Annual Meeting, Toronto, Canada. 
           
Mitchell MD, Williams K, Umscheid CA. The First Four Years of a Hospital-Based Comparative Effectiveness Center:Translating Research Into Practice to Improve the Quality, Safety, and Cost-Effectiveness of Patient Care. Poster presentation at the 2010 Society of Medical Decision Making Annual Meeting, Toronto, Canada.

Umscheid CA, Mitchell MD, Williams K, Brennan PJ : The first 3 years of a hospital-based comparative effectiveness center: translating research into practice to improve the quality, safety and cost-effectiveness of patient care. Poster presentation at 2010 Society of Hospital Medicine Annual Meeting, Washington, DC. April 2010.

Umscheid CA, Hanish A, Chittams J, Hecht T, Sood S, Kean CR, Massary M, Smith CT, Weiner MG. : The impact of a computerized decision support on venous thromboembolism treatment in the inpatient setting. Poster presentation at the 2010 Society of Hospital Medicine Annual Meeting, Washington, DC. April 2010.

Umscheid CA, Hanish A, Chittams J, Hecht T, Sood S, Kean CR, Massary M, Smith CT, Weiner MG. : The impact of a simple computerized decision support on venous thromboembolism prophylaxis in the inpatient setting. Poster presentation at 2010 Society of Hospital Medicine Annual Meeting, Washington, DC. April 2010.

McGlone, SM, Wettstein, ZS, Bailey, RR, Umscheid, CA, Smith, KJ, Muder RR, Lee, BY. : Determining the economic value of nosocomial norovirus outbreak control measures. Poster presentation at Fifth Decennial International Conference on Healthcare-Associated Infections. Atlanta, GA. March 2010.

Umscheid CA, Mitchell MD, Doshi JA, Agarwal R, Williams K, Brennan PJ. : Estimating the proportion of reasonably preventable hospital acquired infections and associated mortality and costs. Oral presentation at 19th Annual Scientific Meeting of the Society for Healthcare Epidemiology of America, San Diego, CA. 2009.

Doshi J, Pengxiang L, Williams K, Fishman N, Mercincavage M, Umscheid CA, Brennan PJ. : An Assessment of the Financial Impact of a Unit Based Clinical Leadership Model at a University Hospital: A Case Study of Reductions in Catheter- Associated Bloodstream Infections (BSI). Oral presentation at 19th Annual Scientific Meeting of the Society for Healthcare Epidemiology of America, San Diego, CA.

Mitchell MD, Umscheid CA. : Application of evidence-based decision-making to purchasing of an imaging system. Poster presentation at 5th Annual Meeting Health Technology Assessment International, Montreal, Quebec, Canada 2008.

Mitchell MD, Agarwal R, Williams K, Umscheid CA. : How technology assessment by hospitals differs from technology assessment by payers.Podium presentation at 5th Annual Meeting Health Technology Assessment International, Montreal, Quebec, Canada 2008.

Mitchell MD, Agarwal R, Williams K, Umscheid CA. : In-house technology assessment at a major academic medical center: The first two years. Poster presentation at 5th Annual Meeting Health Technology Assessment International, Montreal, Quebec, Canada 2008.

Miller J, Agarwal R, Umscheid CA, Williams K. : Chlorhexidine versus povidone-iodine in skin antisepsis: a systematic review and cost analysis to inform initiatives to reduce hospital acquired infections. Poster presentation at SHEA Annual Meeting, Orlando, FL, 2008.

Umscheid CA, Williams K, Kuntz G, Brennan PJ. : A health system's novel approach to evidence-based practice. Poster presentation at SGIM Annual Meeting, Toronto, Canada 2007.

Kuntz G, Seymour AK, Umscheid CA, Williams, KW. : Supporting Evidence-based Medicine in an Academic Health System: A Unique Partnership between the Center for Evidence-based Practice and the Biomedical Library. Poster presentation at Medical Library Association Annual Meeting, Philadelphia, PA 2007.

Umscheid CA, Mitchell MD, Williams K, Brennan PJ : The first 3 years of a hospital-based comparative effectiveness center: translating research into practice to improve the quality, safety and cost-effectiveness of patient care. Poster presentation at 2010 Society of Hospital Medicine Annual Meeting, Washington, DC. April 2010.

Umscheid CA, Hanish A, Chittams J, Hecht T, Sood S, Kean CR, Massary M, Smith CT, Weiner MG. : The impact of a computerized decision support on venous thromboembolism treatment in the inpatient setting. Poster presentation at the 2010 Society of Hospital Medicine Annual Meeting, Washington, DC. April 2010.

Umscheid CA, Hanish A, Chittams J, Hecht T, Sood S, Kean CR, Massary M, Smith CT, Weiner MG. : The impact of a simple computerized decision support on venous thromboembolism prophylaxis in the inpatient setting. Poster presentation at 2010 Society of Hospital Medicine Annual Meeting, Washington, DC. April 2010.

McGlone, SM, Wettstein, ZS, Bailey, RR, Umscheid, CA, Smith, KJ, Muder RR, Lee, BY. : Determining the economic value of nosocomial norovirus outbreak control measures. Poster presentation at Fifth Decennial International Conference on Healthcare-Associated Infections. Atlanta, GA. March 2010.

Umscheid CA, Mitchell MD, Doshi JA, Agarwal R, Williams K, Brennan PJ. : Estimating the proportion of reasonably preventable hospital acquired infections and associated mortality and costs. Oral presentation at 19th Annual Scientific Meeting of the Society for Healthcare Epidemiology of America, San Diego, CA. 2009.

Doshi J, Pengxiang L, Williams K, Fishman N, Mercincavage M, Umscheid CA, Brennan PJ. : An Assessment of the Financial Impact of a Unit Based Clinical Leadership Model at a University Hospital: A Case Study of Reductions in Catheter- Associated Bloodstream Infections (BSI). Oral presentation at 19th Annual Scientific Meeting of the Society for Healthcare Epidemiology of America, San Diego, CA. Poster presentation at University of Pennsylvania Department of Medicine Research Day, Philadelphia, PA. 2009.

Mitchell MD, Umscheid CA. : Application of evidence-based decision-making to purchasing of an imaging system. Poster presentation at 5th Annual Meeting Health Technology Assessment International, Montreal, Quebec, Canada 2008.

Mitchell MD, Agarwal R, Williams K, Umscheid CA. : How technology assessment by hospitals differs from technology assessment by payers.Podium presentation at 5th Annual Meeting Health Technology Assessment International, Montreal, Quebec, Canada 2008.

Mitchell MD, Agarwal R, Williams K, Umscheid CA. : In-house technology assessment at a major academic medical center: The first two years. Poster presentation at 5th Annual Meeting Health Technology Assessment International, Montreal, Quebec, Canada 2008.

Miller J, Agarwal R, Umscheid CA, Williams K. : Chlorhexidine versus Povidone-Iodine in Skin Antisepsis: A Systematic Review and Cost Analyses to Inform Initiatives to Reduce Hospital Acquired Infections. Poster presentation at SHEA Annual Meeting, Orlando, FL, 2008; University of Pennsylvania Department of Medicine Research Day, Philadelphia, PA 2008.

Umscheid CA, Williams K, Kuntz G, Brennan PJ. : A health system's novel approach to evidence-based practice. Poster presentation at SGIM Annual Meeting, Toronto, Canada 2007.

Kuntz G, Seymour AK, Umscheid CA, Williams, KW. : Supporting Evidence-based Medicine in an Academic Health System: A Unique Partnership between the Center for Evidence-based Practice and the Biomedical Library. Poster presentation at Medical Library Association Annual Meeting, Philadelphia, PA 2007.

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Department of Medicine Research Day Awardees

6/12/09 - Congratulations to Jalpa Doshi, PhD on winning the 2009 Department of Medicine Austrian Award for Health Evaluation Research. Dr. Doshi, Director of CEP's Economic Evaluations Unit, presented a poster titled "Assessing the Financial Impact of a Unit Based Clinical Leadership Model at a University Hospital: A Case Study of Reductions in Central Line-Associated Bloodstream Infections ." The poster estimated the impact of the University of Pennsylvania Health System's Unit Based Clinical Leadership quality infrastructure on catheter associated blood stream infections at Penn. The study was performed by Dr. Doshi along with colleagues in the Center for Evidence-based Practice and the Department of Medicine, and was recently presented as an oral abstract by CEP Co-Director Dr. Craig Umscheid at the Annual Society for Healthcare Epidemiology in America Meeting in San Diego. Besides finding reductions in blood stream infections and costs savings resulting from the novel quality infrastructure, the study also provides an example of the challenges faced and approaches used while evaluating healthcare interventions in the presence of multifaceted quality improvement processes in real-world hospital settings.

5/23/08 - Congratulations to Dr. Jeff Miller on winning the 2008 Edward W. Holmes Research Award for Residents and Students in Evaluative Research. Dr. Miller, a third year resident in the Department of Medicine, presented a poster titled "Chlorhexidine versus Povidone-Iodine in Skin Antisepsis: A Systematic Review and Cost Analyses to Inform Initiatives to Reduce Hospital Acquired Infections." It describes the work he performed during his resident elective with Dr. Rajender Agarwal at the Center for Evidence-based Practice. Drs. Miller and Agarwal found that chlorhexidine was more cost-effective than betadine at reducing surgical site infections. Their work informed purchasing decisions and policy changes in UPHS operating rooms.

 

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