Education
1939        B.S.        Pennsylvania State University
1942        Ph.D.      University of Pennsylvania
1947        M.D.       University of Pennsylvania

Research Area of Interests
Acne; rosacea; photoaging; contact sensitization; cutaneous toxicology

Clinical Research Summary
Dr. Kligman is currently developing non-invasive bioengineering techniques to study the pathogenesis and treatment of the above disorders. These are high-tech imaging and measuring techniques which include:
(1) Ultrasound B-scan
(2) Confocal microscopy
(3) Optothermal Coherent Tomography
(4) Digital polarized light photography with cross and parallel filters
(5) Biomechanical instrumentation for measurement of visco-elasticity, using Cutometry.

Selected Publications

1. Kligman, A.M.: Human models for characterizing "Sensitive Skin". Cosm. Derm. 14(3)15-19, 2001.

2. Kolbe, L., Kligman, A.M. and Stoudemayer, T.: Objective bioengineering methods to assess the effects of moisturizers on xerotic leg skin of elderly people. J. Derm. Treatment 11:241-245, 2000.

3. Acne and Rosacea, 3rd Edition completely revised and enlarged. G. Plewig and A.M. Kligman, Springer-Verlag, Berlin, 2000.

4. Kligman, A.M. and Kligman, L.H.: A hairless mouse model for assessing the chronic toxicity of topically applied chemicals. Food and Chem. Tox. 36:867-878, 1998.

5. Kligman, A.M.: The myth of lanolin allergy. Contact Dermatitis 39(3):103-107, 1998.

6. Kligman, A.M. and Lavker, R.M.: Cutaneous Aging: The differences between intrinsic aging and photoaging. Jour. Cutaneous Aging & Cosm. Derm. 1:1, 1988.

7. Mills, O.H. and Kligman, A.M.: Treatment of acne by vitamin A (Retinol). Seminars in Derm. 1:245-249, 1982.

8. Kligman, A.M.: The identification of contact allergens by human assay. III. The Maximization Test. A procedure for screening and rating contact sensitizers. J. Invest. Derm. 47(5):393-409, 1966.