Short Courses: Economic Assessment in Clinical Trials
MDM Short Course PM7
2:00 - 5:30, Sunday October23, 2011
Background: Prospective economic evaluation of clinical trials is an
increasingly important component of the clinical development program
for new clinical therapies. In this course, the faculty and participants will explore issues in the design
and analysis of economic assessments in trials and introduce both standard and recently proposed statistical methods for
these assessments.
Objectives:
• Design, implement and analyze economic outcomes within the
setting of RCTs;
• Evaluate patient-level medical costs; and
• Evaluate stochastic uncertainty in cost-effectiveness analysis
Course Description:The instructors will outline the steps in the
economic evaluation and provide an understanding of the strategic
issues in the design of economic assessments in clinical trials.
Issues related to choice of univariate and multivariate methods
(OLS, log-OLS, GLM) for evaluating and reporting the effect of
treatments on costs will be described and illustrated. The large
number of methods available for reporting on stochastic uncertainty
related to the comparison of costs and effects will be introduced,
strengths and weaknesses of each discussed and preferred methods
for confidence interval estimation highlighted.
Format, Requirements and Target Audience: The course
format is primarily didactic; its content is both theoretical and
applied (with STATA computer software documented to assist in
use). The course is designed for people with some familiarity with
statistics and prospective economic data collection in trials.
Faculty:
- Henry Glick, PhD, University of Pennsylvania
- Jalpa Doshi, PhD, University of Pennsylvania
