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MDM Short Course #10
9:00 - 12:30, Sunday, October 17, 2004

Course Description:

Prospective economic evaluation of clinical trials is an increasingly important component of the clinical development program for new clinical therapies (e.g., treatments, behavioral interventions, and drugs). The statistical methods used for analysis of economic data from prospective studies are constantly evolving. In this course, the faculty and participants will explore issues in the design and analysis of economic assessments in trials and introduce both standard and recently proposed statistical methods for these assessments.

Topics covered will include analysis of patient-level cost data; analysis of costs and effects using seemingly unrelated regressions; and addressing uncertainty in the comparison of costs and effects. The course format is primarily didactic; its content is both theoretical and applied (with computer software documented to assist in use). This course is designed for people with some familiarity with prospective economic data collection in trials.

• Agenda

• Designing Economic Evaluations in Randomized Trials, H. Glick

• Evaluating Treatment Costs in Clinical Trials, J. Doshi

• Evaluating Sampling Uncertainty in Cost-Effectiveness Analysis, H. Glick

Faculty:

• Jalpa Doshi, PhD, University of Pennsylvania

• Henry Glick, PhD, University of Pennsylvania