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9. OXYGEN TOXICITY

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 Experiment Name
9.00 O2 CONVULSIONS IN MAN - CHARACTERISTICS. THERAPEUTIC TRIAL IN SCHIZOPHRENIA (DELAWARE STATE HOSPITAL PATIENTS) - Secure

9.01

 CONVULSIONS LATENT PERIODS - HUMAN

REPORT: Lambertsen, C. J. Respiratory and circulatory actions of high oxygen pressure. Proceedings Underwater Physiology Symposium (I). Goff, L. G. (Ed.). NAS-NRC Publ. No. 377. Washington, DC: National Academy of Sciences-National Research Council, 25-38, 1955.

REPORT: 9.02 EQUIVALENT CONVULSANT DOSES OF O2 AT DIFFERENT PRESSURES-RATS

9.10

 ROLE OF CO2 IN OXYGEN TOXICITY-ANALYSIS, Notes, 1955 (See also 3.00)

9.11

 INTERACTION OF O2 AND CO2 TOXICITY IN MICE

REPORT: Marshall, J.R., and C.J. Lambertsen. Interactions of increased PO2 and PCO2 effects in producing convulsions and death in mice. J. Appl. Physiol. 16: 1-7, 1961.

9.12

 EFFECTS OF HYPERCAPNIA (ACUTE AND CHRONIC), HYPOXIA, AND COMBINED HYPERCAPNIA AND HYPOXIA ON O2 TOLERANCE IN RATS

REPORT: Clark, J.M. Interacting effects of hypoxia adaptation and acute hypercapnia on oxygen tolerance in rats. J. Appl. Physiol. 56: ll9l-ll98, l984.

REPORT: Clark, J.M. Effects of acute and chronic hypercapnia on oxygen tolerance in rats. J. Appl Physiol. 50: 1036-1044, 1981.

REPORT: Clark, J.M. Modification of oxygen tolerance in rats by adaptation to combined hypoxia and hypercapnia. Undersea Hyperbar. Med. 21: 251-264, 1994.

9.13

 RATE OF RECOVERY FROM O2 EXPOSURE -RATS (CLARK, 1981) preliminary expt, relates to 9.12

9.14

 EFFECTS OF O2 EXPOSURE INTERMITTENCY - RATS (CLARK, 1981) part of 9.12

9.15

 HYPEROXIA EFFECTS IN ENDOTOXIN-PRETREATED, OXYGEN-ADAPTED RATS

REPORT: Jackson, R.M. and J.B. Pisarello. The endotoxin-pretreated, oxygen adapted rat model in hyperbaric hyperoxia. Aviat. Space Environ. Med. 55: 709-714, l984.

9.16

 HYPOXIA PREADAPTATION EFFECTS ON OXYGEN INDUCED DEPRESSION OF LUNG ANGIOTENSIN-CONVERTING ENZYME ACTIVITY

REPORT: Jackson, R. and J. Pisarello. Hypoxia preadaptation prevents oxygen induced depression of lung angiotension converting enzyme activity. Am. Rev. Resp. Dis. 130: 424-428, l984.

9.20

 INTERMITTENT O2 EXPOSURE FOR O2 TOLERANCE EXTENSION (See also 9.14, 9.80, 9.82)

9.21

 INTERMITTENT O2 EXPOSURE-GUINEA PIGS, 1954

REPORT: Hall, D.A. The Influence of the Systematic Fluctuation of PO2 upon the Nature and Rate of Development of Oxygen Toxicity in Guinea Pigs. Master’s Thesis in Pharmacology. Philadelphia, PA: Dept. of Pharmacology, University of Pennsylvania, 1967.

9.22

 INTERMITTENT O2 EXPOSURE-HUMAN

REPORT: Hendricks, P.L., D.A. Hall, W.I. Hunter, Jr., and P.J. Haley. Extension of pulmonary O2 tolerance in man at 2 ATA by intermittent O2 exposure. J. Appl. Physiol. 42: 593-599, 1977.

9.30

 O2 TOXICITY - EYE

REPORT: Nichols, C.W., M. Yanoff, D.A. Hall and C.J. Lambertsen. Histological alterations produced in the eye by oxygen at high pressure. Arch. Ophthalmol. 87: 417-421, 1972. Guinea Pig.

9.31

 O2 TOXICITY, EYE-HUMAN (from Expt 9.40) (See also 9.70)

REPORT: Nichols, C.W., C.J. Lambertsen and J.M. Clark. Transient unilateral loss of vision associated with oxygen at high pressure. Arch. Ophthalmol. 81: 70-74, 1969.

9.32

 O2 TOXICITY, EYE-SQUIRREL MONKEY 1971, data, photo.

9.33

 O2 TOXICITY, RABBIT RETINA, GLUCOSE METABOLISM

9.34

 O2 TOXICITY, EYE - RABBIT (MONTABANA) 2 to 5 ATA O2, data tables, figures

9.4 Pulmonary O2 Tolerance


08 February 2000 03:18:19 PM

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