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9. OXYGEN TOXICITY (cont.)

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 Experiment Name
9.40 PULMONARY O2 TOLERANCE. RATE OF DEVELOPMENT OF PULMONARY O2 TOXICITY (See also 9.70, 9.80)

REPORT: Clark, J.M., and C.J. Lambertsen. Pulmonary oxygen tolerance and the rate of development of pulmonary oxygen toxicity in man at two atmospheres inspired oxygen tension. In: Underwater Physiology, III. Lambertsen, C.J., Ed. Baltimore: Williams and Wilkins, 439-451, 1967.

REPORT: Clark, J.M., and C.J. Lambertsen. Rate of development of pulmonary O2 toxicity in man during O2 breathing at 2.0 ata. J. Appl. Physiol. 30: 739-752, 1971.

9.40.1

 PULMONARY MECHANICS EFFECTS (See also 9.70.6, 9.80)

REPORT: Fisher, A.B., R.W. Hyde, R.J.M. Puy, J.M. Clark and C.J. Lambertsen. Effect of oxygen at 2 atmospheres on the pulmonary mechanics of normal men. J. Appl. Physiol. 24: 529-536, 1968.

9.40.2

 PULMONARY CAPILLARY BED EFFECTS

REPORT: Puy, R.J.M., R.W. Hyde, A.B. Fisher, J.M. Clark, J. Dickson and C.J. Lambertsen. Alterations in the pulmonary capillary bed during early O2 toxicity in man. J. Appl. Physiol. 24: 537-543, 1968.

9.40.3

 PULMONARY GAS EXCHANGE EFFECTS

REPORT: Clark, J.M., and C.J. Lambertsen. Alveolar-arterial O2 differences in man at 0.2, 1.0, 2.0 and 3.5 ATA inspired PO2. J. Appl. Physiol. 30: 753-763, 1971.

9.41

 DERIVATION OF PULMONARY AND CNS O2 TOLERANCE CURVES (FROM 9.40)

REPORT: Clark, J.M. Derivation of Pulmonary Oxygen Tolerance Curves Describing the Rate and Development of Pulmonary Oxygen Toxicity in Man. PhD, University of Pennsylvania, Pharmacology, 1970.

9.42

 PULMONARY TOXIC DOSE OF O2 (UPTD, CPTD, PREDICTIVE INDEX)

REPORT: Wright, W.B., Use of the University of Pennsylvania Institute For Environmental Medicine procedure for calculation of cumulative pulmonary oxygen toxicity. U.S. Navy Experimental Diving Unit Report 2-72. Washington, D.C.: 1972.

REPORT: Bardin, H. and C. J. Lambertsen. A Quantitative Method for Calculating Cumulative Pulmonary Oxygen Toxicity: Use of the Unit Pulmonary Toxic Dose (UPTD). Philadelphia, PA: Institute for Environmental Medicine, University of Pennsylvania Medical Center, 1970.

9.42.1

 CONTRIBUTION OF BRONCHIAL CIRCULATION IN PULMONARY O2 TOXICITY - DOG (WRIGHT)

9.42.2

 EFFECT ON THORACIC DUCT LYMPH FLOW-DOG prelim draft

9.43.3

 BRONCHOALVEOLAR POLYMORPHONUCLEAR LEUKOCYTES IN PULMONARY OXYGEN TOXICITY

REPORT: Glass, M., H.J. Forman, E.I. Rotman, J.M. Clark, G.G. Pietra and A.B. Fisher. Bronchoalveolar polymorphonuclear leucocytes in pulmonary oxygen toxicity. J. Hyperbaric Med. 1: 107-121, 1986.

9.50

 MYOCARDIAL FUNCTION AT INCREASED PAO2 - 1 ATA

REPORT: Pelled, B. Effects of Hyperoxia on the Coronary Circulation and Myocardial Function. Masters thesis, 1973.

REPORT: Pelled, B., Y. Seki, F. Ramsey and C.J. Lambertsen. Effects of hyperoxia on the coronary circulation and myocardial function. In: O2 Fifth International Hyperbaric Conference Proceedings, Vol. II. Trapp, W.G., E.W. Banister, A.J. Davison and P.A. Trapp, Eds. Burnaby, Canada: Simon Fraser University, pp. 691-698, 1974.

9.51

 MYOCARDIAL FUNCTION AT INCREASED PAO2 - 3 ATA minimal data, no description

9.60

 O2 EFFECTS ON BODY TEMPERATURE-RATS (PUGLIA)

9.61

 SULFHYDRYL CONCENTRATION IN BRAIN REGIONS-RAT

9.62

 HYPOTHERMIA AND CONVULSIONS RESULTING FROM HYPERBARIC O2 IN RATS AT 4 ATA

REPORT: Fenton, L.H., Beck, G., Djali, S. and M.B. Robinson. Hypothermia induced by hyperbaric oxygen is not blocked by serotonin antagonists. Pharmacol. Biochem. Behav. 44: 357-364, 1993.

REPORT: Fenton, L.H. and M.B. Robinson. Repeated exposure to hyperbaric oxygen sensitizes rats to oxygen-induced seizures. Brain Res. 632: 143-149, 1993.

REPORT: Fenton, L.H. Hyperbaric Oxygen-Induced Hypothermia and Convulsions: Neurotransmitter Activity and the Effect of Previous Exposure to Hyperbaric Oxygen. PhD, University of Pennsylvania, Comparative Medical Science, 1994.

9.63

 EFFECTS OF HYPEROXIA O2 ON BRAIN METABOLIC AND ELECTRICAL FUNCTION -- DATA DOCUMENTED IN FILES OF REPORTS

REPORT: Torbati, D. and K.J. Reilly. Effect of prolonged normobaric hyperoxia on regional cerebral metabolic rate for glucose in conscious rats. Brain Res. 459: 187-191, 1988.

REPORT: Torbati, D. Hyperbaric Oxygenation. In: Encyclopedia of Medical Devices and Instrumentation. Vol. 3. Webster, J.G., Ed. pp. 1564-1583, 1988.

REPORT: Torbati, D. and C.J. Lambertsen. Effects of hyperbaric oxygenation on regional cerebral glucose utilization rate in the awake rat. In: Proceedings of the Eighth International Congress on Hyperbaric Medicine. Kindwall, E.P., Ed. San Pedro, CA: Best, pp. 48-56, 1987.

REPORT: Torbati, D. Oxygen and brain physiologic functions: a review. In: Underwater and Hyperbaric Physiology IX. Bove, A.A., A.J. Bachrach and L.J. Greenbaum, Eds. Bethesda: Undersea and Hyperbaric Medical Soc., pp. 659-690, 1987.

REPORT: Torbati, D., J. Greenberg and C.J. Lambertsen. Regional cerebral glucose metabolic rate during thirty minutes hypoxia of 7% oxygen in adult conscious rats. Neurosci. Lett. 65: 253-258, 1986.

REPORT: Torbati, D. and A. Torbati. Blood glucose as a predictive measure for central nervous system oxygen toxicity in conscious rats. Undersea Biomed. Res. 13: 147-154, 1986.

REPORT: Torbati, D. Regional cerebral metabolic rate for glucose immediately following exposure to 2 atmosphere absolute oxygen in conscious rats. Neurosci. Lett. 55: 109-112, 1985.

REPORT: Torbati, D. Effect of pentobarbital anesthesia on regional cerebral metabolic rate for glucose during hyperbaric oxygenation in rat. Brain Res. 336: 350-353, 1985.

REPORT: Torbati, D. Heparin effects during hyperbaric oxygenation in rats. Life Sciences 36: 147-151, 1985.

REPORT: Torbati, D. and C.J. Lambertsen. The relationship between cortical electrical activity and regional cerebral glucose metabolic rate in rats exposed to 3 atmospheres absolute oxygen. Brain Res. 344: 186-190, 1985.

REPORT: Torbati, D. Effect of propranolol on the electrical activity of the brain during hyperbaric oxygenation in the rat. Undersea Biomed. Res. 12: 423-429, 1985.

REPORT: Torbati, D. Correlation of age and body weight with local cerebral glucose utilization in 8-14 week-old rats. Brain Res. 30l: 143-145, 1984.

REPORT: Torbati, D. Cellular mechanisms of oxygen toxicity. In: Oxygen: An in-depth study of its pathophysiology. 28th Undersea Medical Society Workshop. Bethesda, MD: Undersea Medical Soc., 1984. pp. 377-409.

REPORT: Torbati, D. and C.J. Lambertsen. Alterations in rat local brain and spinal cord glucose utilization following 30 to 60-minute exposure to 2 and 3 ATA O2 and normoxic N2-O2 at 3 ATA. In: Underwater Physiology, VIII. Bachrach, A.J. and M.M. Matzen, Eds. Bethesda: Undersea Medical Soc., 1984. pp. 61-68.

REPORT: Torbati, D., C.J. Lambertsen and J. Greenberg. Regional cerebral glucose utilization rates in rats during asymptomatic period of exposure to 1, 2, and 3, ATA O2. Neuroscience 11: 947-950, 1984.

REPORT: Torbati, D., P. Lo and C.J. Lambertsen. Local cerebral glucose utilization rate following intermittent exposures to 2 atmosphere absolute oxygen. Neuroscience Lett. 50: 79-84, 1984.

REPORT: Torbati, D., J. Greenberg and C.J. Lambertsen. Correlation of brain glucose utilization and cortical electrical activity during development of brain oxygen toxicity. Brain Res. 262: 267-273, 1983.

REPORT: Torbati, D., C.J. Lambertsen. Regional cerebral metabolic rate for glucose during hyperbaric oxygen-induced convulsions. Brain Res. 279: 382-386, 1983.

REPORT: Simon, A.J. and D. Torbati. Effect of hyperbaric oxygen on heart, brain and lung functions in the rat. Undersea Biomed. Res. 9: 263-275, 1982.

REPORT: Torbati, D., A.J. Simon and A. Ranade. Frequency analysis of EEG in rats during the preconclusive period of O2 poisoning. Aviat. Space Environ. Med. 52: 598-603, 1981.

9.7 Predictive Studies V


08 February 2000 03:18:34 PM

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