<< Back to Research Contents


9. OXYGEN TOXICITY (cont.)

# Experiment Name
9.70 PREDICTIVE STUDIES V (PS V): DEFINITION OF OXYGEN EFFECTS AND TOLERANCE IN HUMAN ORGAN SYSTEMS. EXPERIMENTS DATA UNITS.

REPORT: Lambertsen, C. J., J. M. Clark, R. Gelfand, J. B. Pisarello, W. H. Cobbs, J. E. Bevilacqua, D. M. Schwartz, D. J. Montabana, C. S. Leach, P. C. Johnson, and D. E. Fletcher. Definition of tolerance to continuous hyperoxia in man. An abstract report of Predictive Studies V. Underwater and Hyperbaric Physiology IX. Bove, A. A., A. J. Bachrach, and L. J. Greenbaum (Eds.). Bethesda, MD: Undersea and Hyperbaric Medical Society, 717-735, 1987.

9.70.1

ELECTROENCEPHALOGRAPHY. CONVULSIONS.

9.70.2

VISUAL FUNCTIONS (RETINAL, NEURAL PATHWAY, CORTEX)

9.70.3

AUDITORY/VESTIBULAR FUNCTIONS

9.70.4

SOMATOSENSORY EVOKED RESPONSE

9.70.5

MENTAL PERFORMANCE (PERCEPTUAL, COGNITIVE, PSYCHOMOTOR) (SYMPTOMS) 

9.70.6

PULMONARY FUNCTIONS (MECHANICAL, DIFFUSION, ALVEOLAR-ARTERIAL GAS EXCHANGE)

REPORT: Clark, J. M., C. J. Lambertsen, R. Gelfand, N. D. Flores, J. B. Pisarello, M.D. Rossman, and J. A. Elias. Effects of prolonged oxygen exposure at 1.5, 2.0, or 2.5 ATA on pulmonary function in men (Predictive Studies V). J. Appl. Physiol. 86(1): 243-259, 1999.

REPORT: Clark, J. M., r. M. Lackson, C. J. Lambertsen, R. Gelfand, W. D. B. Hiller, and M. Unger. Pulmonary function in men after oxygen breathing at 3.0 ATA for 3.5 h. J. Appl. Physiol. 71(3):878-885, 1991.

9.70.7

CELLULAR AND CHEMICAL COMPOSITION OF BRONCHOALVEOLAR LAVAGE FLUID

9.70.8

PULMONARY VENTILATION/RESPIRATORY CONTROL

REPORT: Gelfand, R., C. J. Lambertsen, J. M. Clark, and E. Hopkin. Hypoxic ventilatory sensitivity in men is not reduced by prolonged hyperoxia (Predictive Studies V and VI). J. Appl. Physiol. 84(1): 292-302, 1998.

9.70.9

THERMAL HOMEOSTASIS

9.70.10

CARDIOVASCULAR FUNCTIONS. VAGAL EFFECT.

9.70.11

LIVER BLOOD FLOW

9.70.12

RENAL FUNCTION

9.70.13

ENDOCRINE ACTIVITY (PLASMA HORMONE LEVELS)

9.70.14

HEMATOLOGIC EFFECTS

9.70.15

ERYTHROCYTE MEMBRANE PHOSPHOLIPID TURNOVER

9.70.16

MUSCLE POWER (RESPIRATORY, SKELETAL)

9.70.17

MUSCLE STRENGTH/ENDURANCE

9.70.18

HANDGRIP STRENGTH (MAXIMUM, ENDURANCE)

REPORT: Clark, J. M., R. Gelfand, N. D. Flores, C. J. Lambertsen, and J. B. Pisarello. Pulmonary Tolerance in Man to Continuous Oxygen Exposure at 3.0, 2.5, 2.0, and 1.5 ATA in Predictive Studies V. Ninth International Symposium on Underwater and Hyperbaric Physiology, Undersea and Hyperbaric Medical Society, 1987.

REPORT: Clark, J. M., C. J. Lambertsen, R. Gelfand, N. D. Flores, J. B. Pisarello, M. D. Rossman, and J. A. Elias. Effects of prolonged oxygen exposure at 1.5, 2.0, or 2.5 ATA on pulmonary function in men (Predictive Studies V). J. Appl. Physiol. 86(1): 243-259, 1999.

REPORT: Clark, J. M., R. M. Jackson, C. J. Lambertsen, R. Gelfand, W. D. B. Hiller, and M. Unger. Pulmonary function in men after oxygen breathing at 3.0 ATA for 3.5 h. J. Appl. Physiol. 71(3): 878-885, 1991.

REPORT: Gelfand, R., C. J. Lambertsen, J. M. Clark, and E. Hopkin. Hypoxic ventilatory sensitivity in men is not reduced by prolonged hyperoxia (Predictive Studies V and VI). J. Appl. Physiol. 84(1): 292-302, 1998.

REPORT: Dise, C. A., J. M. Clark, C. J. Lambertsen, and D. B. P. Goodman. Hyperbaric hyperoxia reversibly inhibits erythrocyte phospholipid fatty acid turnover. J. Appl. Physiol. 62(2): 533-538, 1987.

REPORT: Lambertsen, C. J., J. M. Clark, R. Gelfand, J. B. Pisarello, W. H. Cobbs, J. E. Bevilacqua, D. M. Schwartz, D. J. Montabana, C. S. Leach, P. C. Johnson, and D. E. Fletcher. Definition of tolerance to continuous hyperoxia in man. An abstract report or Predictive Studies V. Underwater and Hyperbaric Physiology IX. Bove, A. A., A. J. Bachrach, and L. J. Greenbaum (Eds.). Bethesda, MD: Undersea and Hyperbaric Medical Society, 717-735, 1987.

PS V DATA AND DOCUMENTATION. PRESERVATION AND ACCESS

EACH EXPERIMENT CONDITION AND DATA UNIT ORGANIZED BY PRESSURE:

3.0 ATA O2
2.5 ATA O2
2.0 ATA O2
1.5 ATA O2
1.0 ATA AIR CONTROLS DURATIONS (SHORT - 3.5 HRS; LONG - 20 HRS)

DATA AND DOCUMENTATION RECORDS OF THE PREDICTIVE STUDY, MAINTAINED IN THE ENVIRONMENTAL BIOMEDICAL STRESS DATA CENTER ACCESSIBLE DATA STORAGE FOR PURPOSES OF OPEN FURTHER ANALYSIS AND CORRELATION, ARE AS FOLLOWS:

Medical Records
Experiments Records
Decompression-Gas and Environmental Parameters Log
Electroencephalographic and Cortical Evoked Potential: Tapes and Recordings
Performance Measurement Tapes
Audio Log
Symptoms Log
Motion Picture Film and Video Tape Log

9.8 Predictive Studies VI


08 February 2000 03:19:08 PM


Copyright ©2000 Unauthorized reproduction of this material is strictly prohibited

For information, contact EBSDC: clambert@mail.med.upenn.edu