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PREDICTIVE STUDIES V (PS V): Oxygen Tolerance and Toxicity.
Major Category: Pulmonary and neurologic O2 tolerance and toxicity (PS V)
Subcategory 9: Respiratory function. Resting. Pulmonary O2 poisoning. Neurologic O2 Poisoning.

Expt. Title: Human tolerance to continuous O2 exposure at 1.5, 2.0, 2.5, and 3.0 ATA. Predictive Studies V. (Expt. 9.70)

Date: 1983-1987

Description: See PS V "Experiment protocols and measurement modules" for general description.

Measurements:

Expiratory minute volume, frequency, tidal volume, end-tidal PCO2, rate of CO2 elimination at rest, peak inspiratory pressures at functional residual capacity and residual volume, peak expiratory pressures at functional residual capacity and total lung capacity.

REPORT: Lambertsen, C.J., J.M. Clark, R. Gelfand, J.B. Pisarello, W.H. Cobbs, J.E. Bevilacqua, D.M. Schwartz, D.J. Montabana, C.S. Leach, P.C. Johnson, and D.E. Fletcher. Definition of tolerance to continuous hyperoxia in man. An abstract report of Predictive Studies V. In: Underwater and Hyperbaric Physiology IX. Proceedings of the Ninth International Symposium on Underwater and Hyperbaric Physiology. Edited by A.A. Bove, A.J. Bachrach, and L.J. Greenbaum. Bethesda: Undersea and Hyperbaric Medical Society, 1987. pp. 717-735.

REPORT: Gelfand, R., J.M. Clark, C.J. Lambertsen, and J.B. Pisarello. Effects on respiratory homeostasis of prolonged continuous hyperoxia at 1.5 to 3.0 ATA in man in Predictive Studies V. In: Underwater and Hyperbaric Physiology IX. Proceedings of the Ninth International Symposium on Underwater and Hyperbaric Physiology. Edited by A.A. Bove, A.J. Bachrach, and L.J. Greenbaum. Bethesda: Undersea and Hyperbaric Medical Society, 1987. pp. 751-761.

REPORT: Lambertsen, C.J. Extension of O2 tolerance in man: Philosophy and significance. Experimental Lung Research 14: 1035-1058, 1988.

REPORT: Lambertsen, C.J., J.M. Clark, R. Gelfand, J. Pisarello, R. Jackson, R. Marsh, W. Cobbs, R. Harner, J. Bevilacqua, D. Fletcher, and D. Montabana. Predictive Studies V - Tolerance of human organs and functions to continuous hyperoxia (ABSTRACT). Undersea Biomed. Res. 11 (Supp.): 34, 1984.

REPORT: Gelfand, R., J.M. Clark, C.J. Lambertsen, R. Jackson, and J. Pisarello. Hyperoxia at 3.0 ATA for 3.5 hours (in Predictive Studies V). Effects on ventilatory parameters (ABSTRACT). Undersea Biomed. Res. 12 (Supp.): 19-20, 1985.

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