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PREDICTIVE STUDIES VII (PS VII): Interactions of Hyperoxia, Exercise, and Immersion in Neurologic O2 Poisoning.
Major Category: Oxygen toxicity and oxygenation. Immersion. Exercise. (PS VII)
Subcategory 11: Hyperoxia, exercise, cerebral circulation.

Stressors: hyperoxia, exercise

Date: 1994-95

Expt. Title: Physiological responses to incremental exercise under hyperoxic and normoxic conditions at 2.0 atmospheres. (Expt. 13.03)

Description:

Nine Subjects performed sequential, 6-minute periods of bicycle ergometer exercise in a dry chamber at 2.0 ATA. The work loads were 50, 125 and 200 watts, first while breathing 100% O2, and afterwards while breathing 10.5% O2. The two periods of exercise were separated by a rest period of at least 30 minutes. This study was preceded by training and then control runs on the same Subjects following the same protocol but at 1 ATA breathing air.

Measurements:

Arterial PCO2, PO2 and pH, body and ambient temperatures, MCA blood flow velocity, ventilation, respiratory frequency and tidal volume, heart rate, rates of uptake of O2 and elimination of CO2, cardiac stroke volume, and mean arterial blood pressure.

REPORT Clark, J. M., R. Gelfand, C. J. Lambertsen, G. Beck, Jr., and K. R. Hardy. Ventilatory, arterial PCO2, and cerebral circulatory responses to incremental exercise during O2 breathing at 2.0 ATA (ABSTRACT). Undersea Hyperbaric Med. 22(Supp.): 69, 1995.

07 February 2000 11:09:31 AM