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EMERGE: Enabling Medical Research Growth in Emergency Medicine


2012 - 2014

Fran Balamuth MD, PhD

Dr. Balamuth completed her undergraduate work at Brown University in 1995.  She then went on to complete the MD/PhD program at the Yale University School of Medicine in 2005.  Her PhD research in Immunobiology involved understanding the molecular mechanisms of T cell differentiation.  She then completed both her residency in Pediatrics and fellowship in Pediatric Emergency Medicine at the Children’s Hospital of Philadelphia (CHOP).  In July 2013, she became an Assistant Professor of Pediatrics at the Perelman School of Medicine at the University of Pennsylvania, and an Attending Physician in the Division of Emergency Medicine at CHOP.

Dr. Balamuth’s current research interests involve improving early identification of patients with sepsis in the emergency department through both clinical factors and biomarker development.  She has helped to build a multi-disciplinary, comprehensive clinical database of patients at CHOP with sepsis spectrum illness.  She plans to collect and analyze biologic specimens from these patients in order to investigate RNA expression patterns and protein expression which may help to predict severity of illness.  This information will be used subsequently to develop novel diagnostic testing in the emergency department setting, and may ultimately lead to the development of a clinical decision rule involving both clinical and biologic factors which will lead to more tailored and effective therapies for sepsis spectrum illness.

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