Emergency Medicine

Active Projects and Grants - CECPR

The Relationship Between the Neighborhood Environment, Stress Reactivity and Aggressive Behavior in a Pediatric Population: Healthy Brains and Behavior. Eugenia Catarina South, M.D., M.S.P.H. This is a secondary data analysis of the Healthy Brain and Behaviors study, a four-year RCT which tested the effect of nutritional supplement and cognitive behavioral therapy on childhood aggression. This study merges several existing datasets to explore the relationship between the physical and social environment and biologic stress reactivity and aggressive behavior in a pediatric population.

Addressing Socioeconomic Health Disparities Through Chronic Stress Reduction: A Randomized Controlled Trial of Blight Remediation. Eugenia Catarina South, M.D., M.S.P.H. Sponsor: Penn SOM. Vacant and abandoned blighted spaces are a ubiquitous neighborhood environmental problem encountered by millions of city dwellers on a daily basis. Urban blight is associated with a variety of poor health indicators, including violent crime, cardiovascular disease, sexually transmitted diseases, and stress. The experience of stress from the conditions of one’s neighborhood may contribute to persistent socioeconomic-based health disparities. The purpose of this study is to examine the impact of a blight removal strategy, specifically abandoned house remediation, on biologically measured and self-reported chronic stress.

Understanding the Benefit of Trauma Center Triage for Injured Older Adults. Mucio Kit Delgado, MD, MS, R03-AG052117, Sponsor: NIH/NIA-R03. Major Goals: To examine the benefit of triage to a trauma center for injured older adults, whether this benefit is heterogeneous according to clinical characteristics, and whether differences in survival following complications explain why trauma center care has not been as beneficial for older adults as it has been for younger adults.

Elucidating College Student, Administrator, and Healthcare Provider Perspectives for the Design of a Novel mHealth Behavioral Economic Intervention to Reduce Binge Drinking. Mucio Kit Delgado, MD, MS, Sponsor: ITMAT CHIBE. Major Goals: To conduct the formative research needed to guide the design of a mobile health intervention that leverages insights from behavioral economics for reducing binge drinking among college students.

Reducing Risky Drinking Using Smartphone Paired Breathalyzers: A Validation Study. Mucio Kit Delgado, MD, MS, Pilot Award, Sponsor: Penn Injury Science Center. Major Goals: To validate the test accuracy of three commercially available smartphone-paired breathalyzers against a police grade handheld breathalyzer for measuring Breath Alcohol Content.

Narratives to Promote Provider Adoption Of Evidence Related to Psychotropic Use for High-Risk Youth. Zachary F Meisel, MD, MPH, MSHP, 183171, Sponsor: WT Grant FDN. Major Goals: A mixed methods randomized trial to develop and test multiple messaging strategies, including narrative communication, to support knowledge transfer of evidence based guidelines related to treatment of behavioral disorders to providers who care for disadvantaged youth in the State of Pennsylvania. A specific goal of this project is to improve the adoption of evidence related to use of certain psychotropic medications to children with behavioral disorders.

Health Economics of Substance Abuse and HCV/HIV Treatment in the Era of Integrated Healthcare. Zachary F Meisel, MD, MPH, MSHP, P30-DA040500, Sponsor: NIH/NIDA (Cornell). Major Goals: To develop and disseminate economic evidence that informs substance use treatment policy and HCV and HIV care of substance users, and to increase the impact of this research by addressing the needs of integrated health system providers and payers.

The Life STORRIED Study: Life Stories for Opioid Risk Reduction in the ED. Zachary F Meisel, MD, MPH, MSHP, CDR-1511-33496, Sponsor: PCORI. Major Goals: The objective is the explore the role that engaged patients can play in minimizing the risk of opioid misuse while achieving adequate pain relief for two painful, but usually self-limited, acute conditions: kidney stones and acute low back pain.

Patient Narratives for Enhancing Risk Communication around Pain Relief in Acute Care Settings. Zachary F Meisel, MD, MPH, MSHP, PCORI Pilot, Sponsor: Penn Center for Therapeutic Effectiveness Research.

Twitter and Cardiovascular Health. Raina M Merchant, MD MSHP FAHA, NIH R01HL122457 (Merchant), Sponsor: NIH/NHLBI. Major Goals: We propose to study the conversation on Twitter about several CV-related diseases. We propose to mine Twitter with the goal of understanding how these data can be used to: predict CV epidemiology, disseminate high impact CV health messages, and engage and communicate with a population of patients with CV disease. The overarching goals of this proposal are to understand the uses and limitations of this communication channel.

Building a Social Mediome: Linking Digital Data with Health Records. Raina M Merchant, MD MSHP FAHA, Pioneer Award, Sponsor: Robert Wood Johnson Foundation. Major Goals: Develop a research database of merged social media and EMR data.


Recent Projects and Grants

Pilot Trial Leveraging Smartphone-paired Breathalyzers, Incentives and Rideshare Credits for Reducing Binge Drinking and Drinking and Driving. Mucio Kit Delgado, MD, MS, Sponsor: TAPITMAT.Major Goals: To pilot test the feasibility of implementing a randomized control trial of a behavioral intervention that combines smartphone-paired breathalyzer, financial incentives and rideshare credits to reduce binge drinking and drinking and driving.

SPIN TRIAL: Stories to Promote Information using Narrative. Zachary F Meisel, MD, MPH, MSHP, R18-HS021956, Sponsor: AHRQ. The SPIN Trial is a mixed-method randomized control trial (RCT) to test an innovative strategy using written narratives to promote the dissemination and utilization of evidence-based guidelines related to opioid prescriptions for emergency physicians. These guidelines were developed, in part, due to a national epidemic of unintentional overdoses from prescribed opioids. The goal of this study was to test two dissemination strategies for the new prescription opioid guideline: narrative and summary. The SPIN Trial represents an opportunity to test a novel strategy around the dissemination of evidence for an important patient-centered topic.

Understanding the Drivers of Hospital Performance for In-Hospital Cardiac Arrest. Raina M Merchant, MD MSHP FAHA, K23-HL109083, Sponsor: NIH/NHLBI.In-hospital cardiac arrest (IHCA) represents a significant burden as an estimated 200,000 arrests occur in hospitalized patients in the United States annually. For these individuals, outcomes are poor and survival rates after IHCA vary from 1-40% across hospitals. This variability among hospitals suggests an opportunity for improvement of care in order to increase survival rates of hospitalized patients. The focus of this research is it identify hospitals with high and low in-hospital cardiac arrest survival rates and the factors which most closely predict IHCA outcomes.