Susan
J. Mandel, M.D., M.P.H.
Professor of Medicine
Associate Chief of the Division of Endocrinology, Diabetes, and Metabolism
Director of Clinical Endocrinology, Diabetes and Metabolism
Director, Endocrinology Fellowship Training Program
Program
Summary
Thyroid cancer
is the most common endocrine cancer and affects 17,000 people
a year. As part of the treatment for thyroid cancer, patients
receive therapy with radioactive iodine. Prior to this therapy,
they undergo whole body scanning with the I-131 isotope
to evaluate the extent of their residual disease after surgery.
We are evaluating the use of the I-123 isotope for these
pre-therapy scans, which has better imaging characteristics
and results in a lower radiation dose to the patients. Our
data have demonstrated this is a superior agent for scanning.
I have established a multidisciplinary Thyroid Nodule Clinic
with Endocrinology/medicine, Ultrasound/Radiology, and Cytology/Pathology
to evaluate patients with nodular thyroid disease. The proper
diagnostic test for euthroid patients with thyroid nodules
is fine-needle aspiration biopsy (FNA). The FNAs are performed
with ultrasound guidance and we are analyzing the incremental
utility of ultrasound-guided FNA in the care of these patients
versus FNA by palpation.
Publications Please visit PubMed
for a complete list of publications.
Mandel SJ, Spencer CA, Hollowell JG. Are detection and treatment of thyroid insufficiency in pregnancy feasible? Thyroid. 2005 Jan;15(1):44-53. PMID: 15687823 [PubMed - in process]
Mandel SJ. A 64-year-old woman with a thyroid nodule. JAMA. 2004 Dec 1;292(21):2632-42. No abstract available. PMID: 15572721 [PubMed - indexed for MEDLINE]
Rickels MR, Mandel SJ. Hypocalciuric hypercalcemia and autoantibodies against the calcium-sensing receptor. N Engl J Med. 2004 Nov 18;351(21):2237-8; author reply 2237-8. No abstract available. Erratum in: N Engl J Med. 2004 Dec 30;351(27):2888. PMID: 15548788 [PubMed - indexed for MEDLINE]
Mandel SJ. Diagnostic use of ultrasonography in patients with nodular thyroid disease. Endocr Pract. 2004 May-Jun;10(3):246-52. Review. PMID: 15310543 [PubMed - indexed for MEDLINE]
