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For additional information, please contact Dr. Morris J. Birnbaum
Phone: (215) 898-5001

Email

 

Morris J. Birnbaum, M.D., Ph.D.  Program Director.
Department of Medicine, Division of Endocrinology, Diabetes and Metabolism
Expertise: Insulin signaling pathways

Current Fellows:

  • Dana Avarhami, mentor: Klaus Kaestner
  • Lauren Fishbein, mentor: Kate Nathanson
  • David Metzger, mentor: Ken Zarat
  • Ray Soccio,  mentor:  Mitch Lazar

Obesity and diabetes mellitus are reaching epidemic proportions worldwide.  In the United States alone, the estimated cost of diabetes in 2007 was $174 billion, including $116 billion in excess medical expenditures and $58 billion in reduced national productivity. The Training Program in Diabetes, Endocrinology and Metabolic Diseases provides superb preparation for those scientists committed to careers in research into diabetes, endocrinology and metabolism. 

The program is designed to accommodate both Ph.D. scientists as well as physician scientists with M.D. or M.D, Ph.D. degrees, pursuing careers in either basic or patient-oriented research.  Our 25 training faculty have primary appointments in seven Medical School Departments and consist of 15 professors, 7 associate professors, and assistant 3 professors.

Training grant faculty bring to the program expertise in b-cell development and function, hormone action, physiology, diabetic complications, genetics in humans and model organisms, transcriptional regulation, patient oriented research, epidemiology and biostatistics. Ultimately, the goal of this program is to help train the next generation of physician and basic researchers in research into the prevention and treatment of diabetes and other endocrine disorders.

Mentors:

Rexford Ahima, M.D., Ph.D.
Associate Professor, Department of Medicine, Division of Endocrinology, Diabetes and Metabolism
Expertise:
The role of adipocyte hormones in energy and glucose homeostasis
Lawrence F. Brass, M.D., Ph.D.
Professor, Departments of Medicine and Pharmacology
Expertise: Thrombosis and hemostasis with an emphasis on platelet and vascular biology
Anne R. Cappola, M.D., Sc.M.
Assistant Professor, Department of Medicine, Division of Endocrinology, Diabetes and Metabolism
Expertise: Hormonal alterations that occur with aging and the clinical impact of these changes, particularly in older women
Vivian G. Cheung, M.D.
Professor, Department of Pediatrics, Division of Endocrinology
Expertise: Genetic mapping of complex traits
Nancy E. Cooke, M.D.
Professor, Department of Medicine, Division of Endocrinology, Diabetes and Metabolism
Expertise: Regulation of human growth hormone gene expression
Harold I Feldman, M.D., M.S.C.E.
Professor, Department of Biostatistics and Epidemiology Department of Pediatrics  Department of Medicine 
Expertise: Epidemiology, patient-oriented research, diabetic kidney disease

Klaus H. Kaestner, Ph.D.
Professor, Department of Genetics
Expertise: Transcription factor regulation of organogenesis and physiology of the liver, and pancreas
Stephen E. Kimmel, M.D., M.S.C.E.
Associate Professor, Department of Biostatistics  and Epidemiology, Department of Medicine 
Expertise: Cardiovascular epidemiology with a focus on drug epidemiology, pharmacogenomics, and adherence to medications
Jake A. Kushner, M.D.
Assistant Professor, Department of Pediatrics, Division of Endocrinology
Expertise: Regulation of beta cell proliferation
Richard Landis, Ph.D.
Professor, Department of Biostatistics and Epidemiology
Expertise: Collaborative biomedical research, and the development and evaluation of methods for the analysis of categorical data
Mitchell A. Lazar, M.D., Ph.D.
Professor and Division Chief
Department of Genetics and Medicine, Division of Endocrinology, Diabetes and Metabolism
Expertise: Signal transduction by nuclear receptors and obesity and insulin resistance
Mark A. Lemmon, Ph.D.
Professor and Chair
Department of Biochemistry and Biophysics
Expertise: Structural and cell biology of growth factor receptor signaling
Susan J. Mandel, M.D., M.P.H.
Professor, Department of Medicine, Division of Endocrinology, Diabetes and Metabolism Department of Radiology
Expertise: Use of sonography in the evaluation of patients with thyroid nodules, the novel introduction of I-123 imaging in differentiated thyroid cancer, and thyroid disease during pregnancy
David  R. Manning, Ph.D.
Professor, Department of Pharmacology
Expertise: The process by which the binding of hormones to cell-surface receptors is translated into the regulation of target enzymes and ion channels.
Franz M. Matschinsky, M.D.
Professor, Department of Biochemistry and Biophysics
Expertise: Understanding the role the intermediary and energy metabolism of pancreatic beta-cells play in fuel stimulated insulin secretion and how these processes are modified by neuron-endocrine factors
Judy L. Meinkoth, Ph.D.
Associate Professor, Department of Pharmacology
Expertise: Normal and aberrant growth regulation in thyroid follicular cells
Ali Naji, M.D., Ph.D.,
Professor, Department of Surgery
Expertise: Modulation of auto-immunity and islet transplantation
Katherine L. Nathanson, M.D.
Assistant Professor, Department of Medicine, Division of Human Genetics
Expertise: Biology and genetics of neuroendocrine tumors
Trevor M. Penning, Ph.D.
Professor, Department of Pharmacology
Expertise: Aldo-Keto Reductases: Roles in Hormonal and Chemical Carcinogenesis
Michael R. Rickels, M.D., M.S.
Assistant Professor, Department of Medicine, Division of Endocrinology, Diabetes and Metabolism
Expertise: Islet function post-tranplantation; Methodologies for quantifying insulin secretion, insulin sensitivity, and glucose counterregulatory responses to hypoglycemia
Rebecca A. Simmons, M.D.
Associate Professor, Department of Pediatrics, Division of Neonatology
Expertise: How intrauterine growth retardation leads to obesity and diabetes in later life
Charles A. Stanley, M.D.
Professor, Department of Pediatrics, Division of Endocrinology
Expertise: Genetic disorders of insulin secretion
Doris A. Stoffers, M.D., Ph.D.
Professor, Department of Medicine, Division of Endocrinology, Diabetes and Metabolism
Expertise: Embryonic development and adult regeneration of the endocrine pancreas
Karen L. Teff, Ph.D.
Adjunct Associate Professor, Department of Medicine, Division of Endocrinology, Diabetes and Metabolism
Expertise: Clinical studies of parasympathetic nervous system regulation of glucose homeostasis, insulin secretion, and hepatic glucose production
Kenneth X. Zaret, Ph.D.
Professor, Department of Cell and Developmental Biology
Expertise: Development of liver and pancreas cells