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More Info
For additional information, please contact
Dr. Morris J. Birnbaum
Phone: (215) 898-5001
Email
Morris J. Birnbaum, M.D., Ph.D. Program Director.
Department of Medicine, Division of Endocrinology, Diabetes and Metabolism
Expertise: Insulin signaling pathways
Current Fellows:
- Dana Avarhami, mentor: Klaus Kaestner
- Lauren Fishbein, mentor: Kate Nathanson
- David Metzger, mentor: Ken Zarat
- Ray Soccio, mentor: Mitch Lazar
Obesity and diabetes mellitus are reaching epidemic proportions worldwide. In the United States alone, the estimated cost of diabetes in 2007 was $174 billion, including $116 billion in excess medical expenditures and $58 billion in reduced national productivity. The Training Program in Diabetes, Endocrinology and Metabolic Diseases provides superb preparation for those scientists committed to careers in research into diabetes, endocrinology and metabolism.
The program is designed to accommodate both Ph.D. scientists as well as physician scientists with M.D. or M.D, Ph.D. degrees, pursuing careers in either basic or patient-oriented research. Our 25 training faculty have primary appointments in seven Medical School Departments and consist of 15 professors, 7 associate professors, and assistant 3 professors.
Training grant faculty bring to the program expertise in b-cell development and function, hormone action, physiology, diabetic complications, genetics in humans and model organisms, transcriptional regulation, patient oriented research, epidemiology and biostatistics. Ultimately, the goal of this program is to help train the next generation of physician and basic researchers in research into the prevention and treatment of diabetes and other endocrine disorders.
Mentors:
| Rexford Ahima, M.D., Ph.D. Associate Professor, Department of Medicine, Division of Endocrinology, Diabetes and Metabolism Expertise: The role of adipocyte hormones in energy and glucose homeostasis |
Lawrence F. Brass, M.D., Ph.D. Professor, Departments of Medicine and Pharmacology Expertise: Thrombosis and hemostasis with an emphasis on platelet and vascular biology |
| Anne R. Cappola, M.D., Sc.M. Assistant Professor, Department of Medicine, Division of Endocrinology, Diabetes and Metabolism Expertise: Hormonal alterations that occur with aging and the clinical impact of these changes, particularly in older women |
Vivian G. Cheung, M.D. Professor, Department of Pediatrics, Division of Endocrinology Expertise: Genetic mapping of complex traits |
| Nancy E. Cooke, M.D. Professor, Department of Medicine, Division of Endocrinology, Diabetes and Metabolism Expertise: Regulation of human growth hormone gene expression |
Harold I Feldman, M.D.,
M.S.C.E. Professor, Department of Biostatistics and Epidemiology Department of Pediatrics Department of Medicine Expertise: Epidemiology, patient-oriented research, diabetic kidney disease |
| Klaus H. Kaestner, Ph.D. Professor, Department of Genetics Expertise: Transcription factor regulation of organogenesis and physiology of the liver, and pancreas |
Stephen E. Kimmel, M.D., M.S.C.E. Associate Professor, Department of Biostatistics and Epidemiology, Department of Medicine Expertise: Cardiovascular epidemiology with a focus on drug epidemiology, pharmacogenomics, and adherence to medications |
| Jake A. Kushner, M.D. Assistant Professor, Department of Pediatrics, Division of Endocrinology Expertise: Regulation of beta cell proliferation |
Richard Landis, Ph.D. Professor, Department of Biostatistics and Epidemiology Expertise: Collaborative biomedical research, and the development and evaluation of methods for the analysis of categorical data |
| Mitchell A. Lazar, M.D., Ph.D. Professor and Division Chief Department of Genetics and Medicine, Division of Endocrinology, Diabetes and Metabolism Expertise: Signal transduction by nuclear receptors and obesity and insulin resistance |
Mark A. Lemmon, Ph.D. Professor and Chair Department of Biochemistry and Biophysics Expertise: Structural and cell biology of growth factor receptor signaling |
| Susan J. Mandel, M.D., M.P.H. Professor, Department of Medicine, Division of Endocrinology, Diabetes and Metabolism Department of Radiology Expertise: Use of sonography in the evaluation of patients with thyroid nodules, the novel introduction of I-123 imaging in differentiated thyroid cancer, and thyroid disease during pregnancy |
David R. Manning, Ph.D. Professor, Department of Pharmacology Expertise: The process by which the binding of hormones to cell-surface receptors is translated into the regulation of target enzymes and ion channels. |
| Franz M. Matschinsky, M.D. Professor, Department of Biochemistry and Biophysics Expertise: Understanding the role the intermediary and energy metabolism of pancreatic beta-cells play in fuel stimulated insulin secretion and how these processes are modified by neuron-endocrine factors |
Judy L. Meinkoth, Ph.D. Associate Professor, Department of Pharmacology Expertise: Normal and aberrant growth regulation in thyroid follicular cells |
| Ali Naji, M.D., Ph.D., Professor, Department of Surgery Expertise: Modulation of auto-immunity and islet transplantation |
Katherine L. Nathanson, M.D. Assistant Professor, Department of Medicine, Division of Human Genetics Expertise: Biology and genetics of neuroendocrine tumors |
| Trevor M. Penning, Ph.D. Professor, Department of Pharmacology Expertise: Aldo-Keto Reductases: Roles in Hormonal and Chemical Carcinogenesis |
Michael R. Rickels, M.D., M.S. Assistant Professor, Department of Medicine, Division of Endocrinology, Diabetes and Metabolism Expertise: Islet function post-tranplantation; Methodologies for quantifying insulin secretion, insulin sensitivity, and glucose counterregulatory responses to hypoglycemia |
| Rebecca A. Simmons, M.D. Associate Professor, Department of Pediatrics, Division of Neonatology Expertise: How intrauterine growth retardation leads to obesity and diabetes in later life |
Charles A. Stanley, M.D. Professor, Department of Pediatrics, Division of Endocrinology Expertise: Genetic disorders of insulin secretion |
| Doris A. Stoffers, M.D., Ph.D. Professor, Department of Medicine, Division of Endocrinology, Diabetes and Metabolism Expertise: Embryonic development and adult regeneration of the endocrine pancreas |
Karen L. Teff, Ph.D. Adjunct Associate Professor, Department of Medicine, Division of Endocrinology, Diabetes and Metabolism Expertise: Clinical studies of parasympathetic nervous system regulation of glucose homeostasis, insulin secretion, and hepatic glucose production |
| Kenneth X. Zaret, Ph.D. Professor, Department of Cell and Developmental Biology Expertise: Development of liver and pancreas cells |
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