Progressive Supranuclear Palsy (PSP)
Progressive Supranuclear Palsy (PSP) is another neurodegenerative disease that causes slowing of movement, loss of balance, and difficulty with speaking and swallowing. The hallmark of this condition is the weakness of the eye movement, beginning with an impaired downward gaze. Areas of the brain the are affected by PSP include the basal ganglia, the substantia nigra, the subthalamus, and the brainstem. Tau accumulation is also evident in this condition.