Faculty/Staff

Geriatrics Education
Clinical Care

Research

Grant Funding


Ralston Center



Robert J. Pignolo, M.D., Ph.D.

Assistant Professor of Medicine
Staff Physician, Philadelphia VAMC
Collaborative Faculty, McKay Laboratory of Orthopaedic Surgery Research
Fellow of the Institute on Aging


University of Pennsylvania
Division of Geriatric Medicine
Ralston-Penn Center
Room 321
3615 Chestnut Street
Philadelphia, PA 19104

Telephone: (215) 898-2330
Facsimile: (215) 573-8684
E-mail: robert.pignolo@uphs.upenn.edu

Education

1983 BA University of Pennsylvania
1995 PhD University of Pennsylvania
1998 MD Medical College of Pennsylvania (MCP) and Hahnemann University (HU) School of Medicine

Postgraduate Training and Fellowship Appointments
 

1993 - 1996 Post-doctoral Research Fellow, MCP
1998 - 1999 Intern in Medicine, MCP/HU
1999 - 2001 Resident in Medicine, MCP/HU
2001 - 2003 Fellow in Geriatric Medicine, University of Pennsylvania
2002 - 2003 Post-doctoral Research Fellow, University of Pennsylvania

  Clinical/Research Interests
  1. Cellular senescence
  2. Osteoporosis and metabolic bone disease
  3. Osteobiology of aging
  4. Stem cells, differentiation, and aging

Biographical Sketch


Robert Pignolo is a clinician-scientist whose areas of expertise include cellular and molecular biology of aging, osteoporosis, and metabolic bone disease. His important contributions to the field of cellular senescence has significance to growth control and transformation, differentiation, angiogenesis, and mechanisms of cellular aging. He first isolated and characterized a gene now shown to be a potent angiogenesis inhibitor currently in clinical trials as a potential treatment for age-related macular degeneration. These contributions are represented in professional journals and include original papers, review articles and book chapters. As a clinician-scientist, his areas of interest extend to encompass the biology of bone metabolism as it relates to important issues in geriatrics such as osteoporosis. In addition, he runs the Osteoporosis Clinic in the Geriatrics and Extended Care Service at the Philadelphia VA medical center. He is also co-director of the Frontiers in Aging Course offered as an elective to fourth-year medical students.
 

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