Education | Health Care | Research | Site Map

Division of Infectious Disease
Division of Infectious Disease
Fellowship Program
Clinical Programs
Penn CDC Prevention Epicenters Program
Clinical Trials
Botswana-UPenn Partnership
Adjunct Faculty
Administrative Contacts
Outpatient Clinics




Robert Gross, M.D., M.S.C.E.

Robert Gross is an Associate Professor in Medicine in the Division of ID and Associate Professor of Epidemiology in the Department of Biostatistics and Epidemiology as well as a Senior Scholar in the Center for Clinical Epidemiology and Biostatistics where he received formal training in clinical research culminating in a Masters of Science in Clinical Epidemiology. His research is focused on clinical and virological outcomes in the treatment of HIV infection. A particular interest is the problem of adherence to antiretroviral therapy including methods of measurement of adherence, changes in adherence over time, barriers to adherence in both developed and developing world settings, and trials of adherence interventions. Other interests include HIV pharmacoepidemiology more broadly, including observational studies and clinical trials of antiretroviral therapy, and HIV health services research. He serves as a clinical research mentor to fellows in the Masters of Clinical Epidemiology as well as to medical students and residents interested in pursuing HIV clinical research interests in Philadelphia and abroad (e.g., Botswana, Dominican Republic). Dr. Gross's outpatient clinical work is focused on the care of HIV patients and is based at the Philadelphia Veterans' Administration Medical Center. His inpatient work is divided between HIV and general ID at both the Philadelphia VA and the Hospital of the University of Pennsylvania.

Selected publications:

Bisson GP, Robertson A, Weinstein R, Gaolathe T, Frank I, Gross R. : Antiretroviral failure despite high levels of adherence: discordant adherence-response relationship in Botswana. _JAIDS_ 49(1): 107-110, Sept 2008


Bisson GP, Gross R, Bellamy S, Chittams J, Hislop M, Regensberg L, Frank I, Maartens G, Nachega JB. : Adherence Assessed by Pharmacy Refill Compared With CD4 Count Monitoring for Predicting Virologic Failure Among HIV-Infected Adults on Antiretroviral Therapy. _PLoS Med _ 5(5): e109, May 2008.

Holmes WC, Bilker W, Wang H, Chapman J, Gross R.: HIV/AIDS-Specific Quality of Life and Adherence to Antiretroviral Therapy Over Time. _JAIDS_ 1(46): 323-7, 2007.

Gross R, Yip B, Lo Re V III, Wood E, Alexander CS, Harrigan PR, Bangsberg DR, Montaner JSG, Hogg RS. A Simple Dynamic Measure of Antiretroviral Adherence Predicted Failure to Maintain HIV Suppression. Journal of Infectious Diseases. 2006;194:1108-1114.

Gross R, Zhang Y, Grossberg R. Medication Refill Logistics and Refill Adherence in HIV. Pharmacoepi Drug Safety. 2005;14(11): 789-793.

Grossberg R, Zhang, Y, Gross R. Time-to-Prescription-Refill Measure Predicted Changes in Viral Load in HIV. Journal of Clinical Epidemiology. Journal of Clinical Epidemiology. 2004; 57(10)1107-1110.

Gross R, Bilker WB, Friedman HM, Coyne JC, Strom BL. Provider Inaccuracy in Assessing Adherence and Outcomes with Newly Initiated Antiretroviral Therapy. AIDS. 2002, 16:1835-1837.

Gross R, Bilker WB, Friedman HM, Strom BL. Effect of Adherence to Newly Initiated Antiretroviral Therapy on Plasma Viral Load. AIDS. 2001, 15:2109-2117.

Robert Gross, M.D., M.S.C.E.
Center for Clinical Epidemiology and Biostatistics
804 Blockley Hall
423 Guardian Drive
Philadelphia, PA 19104-6021
(215) 898-2437

Medical School: Cornell University
ID Training: University of Pennsylvania
Masters Degree In Clinical Epidemiology:
University of Pennsylvania
Academic Rank: Associate Professor of Medicine (Infectious Disease) and Epidemiology