Faculty

Vincent Lo Re III, M.D., M.S.C.E.

Dr. Lo Re is an Assistant Professor in the Division of Infectious Diseases and Department of Biostatistics and Epidemiology and a Senior Scholar in the Center for Clinical Epidemiology and Biostatistics. He is also an attending physician in the Viral Hepatitis Clinic and Infectious Diseases Consultation Service at the Penn Presbyterian Medical Center, an affiliate hospital in the University of Pennsylvania Health System.

Clinical and Research Interests
Dr. Lo Re’s research focuses on clinical outcomes of chronic viral hepatitis infection in HIV-infected patients. He is conducting epidemiologic studies to examine novel risk factors for decompensated cirrhosis among HIV/hepatitis C-coinfected patients and is working to develop and internally validate a clinical predictive index to stratify HIV/hepatitis C patients according to their risk of progression to hepatic decompensation. He has also examined the prevalence, risk factors, and clinical significance of occult hepatitis B virus infection in HIV-infected patients. Additional studies are examining non-hepatic outcomes of chronic viral hepatitis infection in HIV, particularly abnormalities in bone mineral density and fractures.

Dr. Lo Re also evaluates clinical outcomes of hepatitis therapy in the setting of HIV. Recent work has examined the incidence and risks factors for anemia and weight loss during hepatitis C therapy among HIV-infected patients. Another active area of research is adherence to combination pegylated interferon and ribavirin hepatitis C therapy. Methodologic interests include use of population-based databases for epidemiologic research, ascertainment and adjudication of clinical outcomes, and pharmacoepidemiology.

Selected publications:

Lo Re V 3rd, Amorosa VK, Localio R, O’Flynn R, Teal V, Dorey-Stein Z, Kostman JR, Gross R. Adherence to hepatitis C virus therapy and early virologic outcomes. Clin Infect Dis. In Press.

Butt AA, Tsevat J, Leonard A, Shaikh OS, McMahon D, Khan UA, Dorey-Stein Z, Lo Re V 3rd. Effect of race and HIV coinfection upon treatment prescription for HCV. Int J Infect Dis. In Press.

Lo Re V 3rd, Wertheimer B, Localio AR, Kostman J, Dockter J, Linnen J, Giachetti C, Tebas P, Frank I, Strom BL, Gross R. No increased incidence of transaminitis among HIV patients with occult hepatitis B. J Clin Virol 2008; 43: 32-6.

Lo Re, Vincent 3rd. Kostman, Jay R. Amorosa, Valerianna K.: Management complexities of HIV/hepatitis C virus coinfection in the twenty-first century. Clin Liver Dis 2008; 12: 587-609.

Lo Re V III, Frank I, Gross R, Synnestvedt M, Localio AR, Kostman JR, Strom BL. Validity of self-reported hepatitis B and C virus infections among HIV-infected patients. J Clin Epidemiol 2007; 60: 294-9.

Lo Re V III, Frank I, Gross R, Dockter J, Linnen JM, Giachetti C, Tebas P, Synnestvedt M, Localio AR, Kostman JR, Strom BL. Prevalence, risk factors, and outcomes for occult hepatitis B virus infection among HIV-infected patients. J Acquir Immune Defic Syndr 2007; 44: 315-20.

Lo Re V III, Kostman JR, Gross R, Reddy KR, Mounzer K, Zemel BS, Rennert H, Stieritz DD, Putt M, Frank I, Strom BL. Incidence and risk factors for weight loss during dual HIV/hepatitis C virus therapy. J Acquir Immune Defic Syndr 2007; 44: 344-50.

Contact:
Vincent Lo Re III, M.D., M.S.C.E.
809 Blockley Hall
423 Guardian Drive
Center for Clinical Epidemiology and Biostatistics
University of Pennsylvania School of Medicine
Philadelphia, PA 19104 USA
E-mail: vincentl@mail.med.upenn.edu
Office Telephone: (215) 573-5964

Education:
Medical School: University of Pennsylvania, 1992-1997
Internal Medicine Residency: University of Pennsylvania, 1997-2001
ID Training: University of Pennsylvania, 2001-2003
Master’s Degree in Clinical Epidemiology: University of Pennsylvania, 2002-2005
Academic Rank: Assistant Professor of Medicine and Epidemiology