Faculty

Joel Maslow, M.D., Ph.D.

Dr. Maslow is Associate Dean for Research at the University and Associate Chief of Research at the Philadelphia Veterans Administration Medical Center. Dr. Maslow has active research on the molecular epidemiology and evolution of fluoroquinolone resistance in E coli. Current work is examining INH toxicities and its relationship to age and MDR-TB in Zambian prisons. Other work includes study of the molecular epidemiology and pathogenesis of Mycobacterium avium. His laboratory is examining the role of the surface glycopeptidolipids (GPL) in the pathogenesis of this organism through the construction of isogenic mutants within the GPL biosynthetic pathway to determine structure-function relationships as it pertains to pathogenesis. In addition, the laboratory has characterized a hemolysin expressed by M. avium and is investigating its role in intracellular bacterial survival. Dr. Maslow has also published extensively on mycobacterial infections in animals, in particular in elephants.

Irani VR and JN Maslow. 2005. Induction of murine macrophage TNF-alpha synthesis by Mycobacterium avium is modulated through complement-dependent interaction via complement receptors 3 and 4 in relation to M. avium glycopeptidolipid. FEMS Microbiol Lett. 246 (2): 221-8

Maslow JN, B Lee, E Lautenbach. 2005. Fluoroquinolone-resistant Escherichia coli in a long term facility. Emerg Infect Dis 11 (6): 889-894

Zhu M, JN Maslow, SK Mikota, R Isaza, L Peddie, F Dunker, J Peddie, H Riddle, CA Peloquin. 2006. Dose selection and pharmacokinetics of rifampin in the treatment of tuberculosis of elephants. J Vet Pharmacol Therap 29: 581-585.

Education:
Medical School: Jefferson Medical College
ID Training: Boston University
Academic Rank: Associate Professor of Medicine; Associate Vice Dean for Research