Basic Sciences in the Penn Infectious Diseases Fellowship
Within the Infectious Diseases division, basic research-oriented fellows will have the opportunity to work with faculty in the Division of Infectious Diseases or across the University. A wealth of relevant research opportunities exist at Penn, with research programs spanning virology, bacteriology and fundamental immunology and biochemistry.
- Faculty members in the infectious diseases division are members of the Cell and Molecular Biology, Biochemistry and Molecular Biophysics, Immunology and Pharmacology graduate groups. Each of these groups are broadly inclusive programs at Penn focused on the training of graduate students and post-doctoral fellows.
- Infectious diseases research space is situated adjacent to the Microbiology department space in Johnson Pavilion, making for extensive collaborative interfaces with the basic science department.
- Infectious diseases researchers and fellows are regular participants in the seminar series in Microbiology, including weekly Virology, Parasitology, Bacteriology seminars, Immunology, and Biochemistry.
- Penn boasts a prominent Center for AIDS Research (CFAR), coordinating clinical trials, international studies and basic science research.
- Penn's Institute for Immunology spans across departments to provide a link for researchers interested in host factors relevant to infectious diseases.
- The Penn/CHOP Microbiome program offers rich resources for understanding basic science and translational questions involving the many microbes that colonize niches relevant to human health and disease.
News Items in basic science research in the Penn Infectious Diseases community.
- The promising new approach that seeks to make immune cells resistant to HIV has been lead by Carl June working with Pablo Tebas from our division. Their report at the recent CROI meeting was featured on the Philadelphia Inquirer.
- Dr. Rahul M. Kohli has recently joined the Infectious Diseases division, with a secondary appointment in Biochemistry. His laboratory is initiated a research program focused on enzymes that generate genomic diversity, including those relevant for the development of drug resistance.
- Pioneering HIV researchers Drs. Beatrice Hahn and George Shaw will be joining Penn Medicine in 2011.
- The basic science behind herpes virus infections has been the focus on the well-recognized annual "Herpesvirus Symposium" sponsored by the ID division for the last 10 years.
- In a recent publication, Dr. Stuart Isaacs and collaborators have demonstrated the efficacy of a protein-based smallpox vaccine in a primate poxvirus infection model system, offering safety advantages over current poxvirus live-virus vaccines.
- The latest methods for generating induced pluripotency stem cells latest methods for generating induced pluripotency stem cells built upon Dr. Drew Weissman’s advances in generating synthetic mRNA that is immunologically tolerated.