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"Specialized Center of Research in Acute Lung Injury"

Click here for Project and Core Descriptions.

SCOR WORK-IN-PROGRESS MEETINGS
(All SCOR members should attend)

April 1st, 2003 Aron Fisher, M.D.   Profile
June 5th, 2003 -
Aug 7th, 2003 -
Oct 2nd, 2003 -
Dec 3rd, 2003 -

ALL W-I-P MEETINGS:   12:15 till 1:30 in the IFEM Seminar Room.

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This page updated 3/21/03

SCOR STEERING COMMITTEE MEETINGS 2003
(Open to Steering Committee members only)


May 1st, 2003  12:15 PM
July 3rd, 2003  12:15 PM
September 4th, 2003  12:15 PM
November 6th, 2003  12:15 PM
SCOR External Advisory Group Meetings
None scheduled at this time

 

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Projects and Cores  

Project 2: 
Endothelial Generation of ROS in Lung Ischemia
Project Leader: Aron B. Fisher, M.D.
Shampa Chatterjee, Ph.D.
Zhihua Wei, Ph.D.

Project 3: 
Biomarkers of Oxidant Stress in ARDS
Project  Leader: Paul N. Lanken, M.D.
Co-Investigators:
William Hanson, M.D.
Michael Russell, M.D.
Mike Shapiro, M.D.

Project 4:
Augmentation of Antioxidant Defenses by Immunotargeting
Project Leader: Vladimir Muzykantov, M.D., Ph.D.
Co-Investigators: Steven Albelda, M.D.
Melpo Cristofidou, Ph.D.
Juan Carlos Murciano, Ph.D.

Core A: 
Clinical Core

Project Leader: Paul N. Lanken, M.D.
Co-Investigator: Robert Lowe, M.D.
Core B: 
Biostatistics and Data Management

Core Leader: J. Richard Landis, Ph.D.
Co-Investigator: WenSheng Guo, Ph.D.
Core C: 
Analytical Core

Core Leader: Harry Ischiropoulos, Ph.D.
Co-Investigator: John Lawson, M.S.
Core D: 
Cell Culture Core Laboratory
Core Director: Sandra R. Bates, Ph.D.
Co Investigator: Melpo Christofidou, Ph.D.
Core E: 
Administrative Core
Core Director: Aron B. Fisher, M.D.
 

 

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SCOR Publications


Current Publications 1999-2000

1. Tozawa, K., Al-Mehdi, A.B., Muzykantov, V. & Fisher, AB - In situ imaging of intracellular calcium with ischemia in lung subpleural microvascular endothelial cells. Antioxidants and Redox Signaling, 1:145-153, 1999

2. Wei, Z., Costa, K., Al-Mehdi, A.B., Dodia, C., Muzykantov, V. & Fisher, A.B. - Simulated ischemia in flow adapted endothelial cells leads to generation of reactive oxygen species and cell signaling. Circulation Research, 85:682-689, 1999.

3. Al-Mehdi, A.B., Zhao, G., Tozawa, K., & Fisher, A.B., - Depolarization-associated iron release with abrupt reduction in pulmonary endothelial shear stress in situ. Antioxidants and Redox Signaling, 2, 335-345

4. Gole MD, Souza JM, Choi I, Hertkorn C, Malcolm S, Foust RF, Finkel B, Lanken PN, Ischiropoulos H. Plasma proteins modified by tyrosine nitration in acute respiratory distress syndrome. Am J Physiol Lung Cell Mol Physiol 278:L961-L967, 2000. 

5. A.Gow, F.Bronco, M.Cristofidou-Solomidou, L.Black-Schultz, S.Albelda 
and V.Muzykantov - Immunotargeting of glucose oxidase to endothelial cells induces intracellular generation of hydrogen peroxide and oxidative stress. Am.J.Physiol. 277:L271-281, 1999.

6. M.Cristofidou-Solomidou, G.Pietra, C.Solomides, E.Argiris, D.Harshaw,
G.FitzGerald, S.Albelda and V.Muzykantov - Immunotargeting of glucose oxidase to endothelium in vivo causes oxidative vascular injury in the lungs. Am.J.Physiol. 278:L794-L805, 2000.

7. Al-Mehdi, A.B., Song, C., Tozawa, K. & Fisher, A.B. - Ca2+- and Phosphatidylinositol 3-kinase dependent Nitric Oxide Generation in Lung Endothelial Cells in Situ with Ischemia. Journal of Biological Chemistry (JBC) - Vol 275, No 51: pp 39807-39810, 2000.



SCOR Staff List

Project / Core Leaders

PROJECT/
Core

ROLE on Project

dept. affiliation

Aron B. Fisher, M.D. 2, E Project & Core Leader Physiology
Harry Ischiropoulos, Ph.D. C Core Leader Pediatrics
Sandra Bates-Kenney, Ph.D. D Core Leader IFEM
J. Richard Landis, Ph.D. B Core Leader Biostat. & Epidem.
Paul N. Lanken, M.D. 3, A Project & Core leader Medicine
Vladimir Muzykantov, M.D., Ph.D. 4 Project Leader Pharmacology
Co-Investigators
Steven Albelda, M.D. 4 Co-Investigator Medicine
Abu Al-Mehdi, M.D., Ph.D. 2, 4 Co-Investigator IFEM
Shampa Chatterjee, Ph.D. 2 Co-Investigator IFEM
Sheldon I. Feinstein, Ph.D. 2 Co-Investigator IFEM
C. William Hanson, III, M.D. 3 Co-Investigator Anesthesia
John Lawson, M.S. C Co-Investigator Pharmacology
Melpo Christofidou, Ph.D. 4 Co-Investigator Medicine
Michael W. Russell, M.D. 3 Co-Investigator Anesthesia
Michael B. Shapiro, M.D. 3 Co-Investigator Surgery
WenSheng Guo, Ph.D. B Co-Investigator Biostat. & Epidem.
Research Specs. / Techs.
Kristine DeBolt D Research Specialist IFEM
Frank Harris A Medical Technician Pathology
Anu Thomas  4 Research Specialist IFEM
Lisa Tyl C Research Specialist Pharmacology
Caryn Hertkorn C Research Specialist Pediatrics
Tom Friel
Research Support personnel
Robert Curley, MS B Tech. Director Biostat. & Epidem.
Lisa Douglas, RN, CCRN A Research Coordinator Medicine
Barbara Finkel, MSN, CCRC 3, C Research Coordinator Medicine
Elizabeth Phillips, B.S. B Mngr. Proc. Dev. Biostat. & Epidem.
Heather Steinberger, RN, CCRN A Research Coordinator Surgery
Administration
Lorraine Evans E Secretary IFEM
Elizabeth Moore E Clin. Administrator IFEM
Colleen O'Brien E Secretary IFEM
Post Doc Fellows/
Visiting Scientist
project/
core
role on project dept. affiliation
Shampa Chatterjee, Ph.D. 2 Post-Doctoral IFEM
Zhihua Wei, M.D. 2 Post-Doctoral IFEM
Juan Carlos Murciano, Ph.D. 4 Post-Doctoral IFEM
Rainer Wiewrodt, Ph.D. 4 Post-Doctoral Medicine
Consultant
Sergei Danilov, M.D., Ph.D. 4 Consultant
Garrett A. FitzGerald, M.D. 3 Consultant
Ellen J. Mackenzie, Ph.D. 3 Consultant
C. William Schwab, M.D. 3 Consultant
Steering Committee
Steven Albelda, M.D. Medicine
Aron B. Fisher, M.D. Physiology
Harry Ischiropoulos, Ph.D. Pediatrics
Sandra Bates-Kenney, Ph.D. IFEM
J. Richard Landis, Ph.D. Biostat. & Epidem.
Paul Lanken, M.D. Medicine
Vladimir Muzykantov, M.D., Ph.D. Pharmacology
Alan Schreiber, M.D. Medicine
Internal Advisory Board
Douglas Cines, M.D.
Peter Davies, Ph.D.
Garret FitzGerald, Ph.D.
Elliot Levine, Ph.D.
Edward Macarak, M.D.
Brian Strom, M.D., M.P.H.
David Wilson, M.D.

 

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