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2000-2004 IME Trainee-Authored Peer Reviewed Papers

Aranda-Espinoza H., H. Bermudez, F. S. Bates, D. E. Discher, (2001) Electromechanical Limits of Polymersomes. Physical Review Letters 87:208-301.

Aranda-Espinoza, H., P. Carl, P. Janmey, J. F. Leterrier, D. E. Discher, Domain Unfolding in Neurofilament Sidearms: Effects of Phosphorylationand ATP. FEBS Letters 531 (2002) 397-402.

Aranda-Espinoza, H. Yi Chen, N. Dan, T. C. Lubensky, P.Nelson, L. Ramos, and D.A. Weitz. (2000). Electrostatic Repulsion of Positively Charged Vesicles and Negatively Charged Objects. Science 285 394-396.

Asanuma K, Magid R, Johnson C, Nerem RM, Galis ZS. Uniaxial strain upregulates matrix-degrading enzymes produced by human vascular smooth muscle cells. Am J Physiol Heart Circ Physiol. 2003 May;284(5):H1778-84.

Bermudez, H. Aranda-Espinoza H., Hammer, D. A.. Discher D. E. Pore Stability and Dynamics in Polymer Membranes. Europhysics Letters 64 (2003) 550.

Byfield, F. Aranda-Espinoza, H., Romanenko V,. Rothblat G, Levitan I.. Cholesterol Depletion increases Membrane Stiffness of Aortic Endothelial Cells: Dependence on F-actin. Biophysical Journal In press.

Clark J, Li Q, Palmatory E, Brittin R, Narula NR, Mohler ER, Gorman R, Levy RJ. 2004. MMP9 Mechanisms in Calcific Aortic Stenosis. Circulation Research, In press.

Clark J, Schoen F, Ogle M, Ashworth P, Levy RJ. 2004. Prevention of Calcific Degeneration of Stentless Porcine Aortic Bioprosthetic Heart Valves with Combined Differentially Applied Ethanol and AlCl3 Pretreatments: 150 Day Sheep Safety and Efficacy Studies. Ann Thorac Surg, In press.

Dalhaimer P., Discher D.E., Janmey P., Aranda-Espinoza H.. Flexibility Transitions and Loop Conformations in Irreversible Polymer Adsorption. Physical Review Letters In press.

Dalhaimer P., F. S. Bates, H. Aranda-Espinoza, and D. E. Discher. (2003) Hydrodynamics of Polymer Membranes. Comptes Rendus Series IV Physics-Astrophysics 4:251-.

Ding S, Horn R. 2003. Effect of S6 Tail Mutations on Charge Movement in Shaker K+ Channels. Biophysical Journal 84: 295-305,

Ding, S., Messan C, Haydon P. 2004. Electrophysiological and pharmacological characterization of ion channels in human brain progenitor cells (hBPCs). Biophysical Journal In press.

Dogic Z., Zhang J.,. Lau, A.W.C Dalhaimer P., Aranda-Espinoza, H. Discher, D. Janmey, P. A. Kamien R.D., Lubensky, T.C. Yodh A. Elongation and Fluctuations of Semi-flexible Polymers in a Nematic Solvent. Physical Review Letters (2004) In press.

Dubb, A., R. Gur, B. Avants, J. C. Gee. 2003. Characterization of sexual dimorphism in the human corpus callosum using templatedeformation. Neuroimage, 20: 512-519.

Gee JC, Sundaram TA, Hasegawa I, Uematsu H, Hatabu H. Characterization of Regional Pulmonary Mechanics from Serial MRI Data . Academic Radiology 10:1147-1152, 2003.

Georges, P. O. Wagner, P. Janmey. 2004. Biopolymer Networks and Cellular Mechanosensing. Gravitational and Space Biology Bulletin, In press.

Ghazvini-Boroujerdi M, Clark J, Narula NR, Palmatory E, Connolly JM, DeFelice S, Xu J, Jian B, Hazelwood S, Levy RJ. Egr-1 in Calcific Aortic Valve Disease. J Heart Valve Dis., in press.

Giakos GC, Chowdhury S, Shah N, Vedantham S, Passerini AG, Suryanarayanan S, Nemer R, Mehta K, Patnekar N, Sumrain S, Nataraj K, Scheiber C. (2001) Signal-to-noise measurements utilizing a novel dual-energy multimedia detector. IEEE Transactions 50(4):910-914.

Goel M.S., S.L. Diamond. (2002). Adhesion of normal erythrocytes at depressed venous shear rates to activated neutrophils, activated platelets, and fibrin polymerized from plasma. Blood. 100:3797-3806

Goel M.S., S.L. Diamond. Factor VIIa- -mediated tenase function on activated platelets under flow. Journal of Thrombosis and Haemostasis. In press (2004). (To be published with Editor's Commentary.)

Goel M.S., S.L. Diamond. Neutrophil cathepsin G promotes prothrombinase and fibrin formation under flow by activating fibrinogen-adherent platelets. Journal of Biological Chemistry. 278, 9458 (2003).

Goel M.S., S.L. Diamond. (2001). Neutrophil Enhancement of Fibrin Deposition under Flow through platelet-dependent and independent mechanisms. Arterioscler Thromb Vasc Biol. 21, 2093

Janmey, P.A., Xian, W., Flanagan, L.A. 2000. Controlling cytoskeleton structure by phosphoinositide-protein interactions: phosphoinositide binding protein domains and effects of lipid packing. Chem Phys Lipids. 101:93-107.

Ji, J.Y., Diamond ,S.L. Exogenous nitric oxide activates the endothelial glucocorticoid receptor. Biochem Biophys Res Commun. In press.

Ji , J.Y., Jing H,, Diamond, S.L. Arterial shear stress is anti-inflammatory: Flow attenuates TNF activation of human endothelium. Am J Physiol Heart Circ Physiol. In press.

Ji, J.Y., Jing ,H., Diamond, S.L. Shear stress causes nuclear localization of endothelial glucocorticoid receptor and expression from the GRE promoter. Circ Res. 2003;92:279-85.

Khatri JJ, Johnson C, Magid R, Lessner SM, Laude KM, Dikalov SI, Harrison DG, Sung HJ, Rong Y, Galis ZS. Vascular oxidant stress enhances progression and angiogenesis of experimental atheroma. Circulation. 2004 Feb 3;109(4):520-5.

Magid R, Martinson D, Hwang J, Jo H, Galis ZS. Optimization of isolation and functional characterization of primary murine aortic endothelial cells. Endothelium. 2003;10(2):103-9.

Magid R, Murphy TJ, Galis ZS. Expression of matrix metalloproteinase-9 in endothelial cells is differentially regulated by shear stress. Role of c-Myc. J Biol Chem. 2003 Aug 29;278(35):32994-9.

P.J. Photos, H. Bermudez, D.A. Hammer, D.E. Discher, H. Aranda-Espinoza Hairy Holes: A Mechanism for Pore Stabilization in Membranes. Langmuir In press

P.J. Photos, L. Bacakova, B.M. Discher, F.S. Bates, D.E. Discher, Polymer Vesicles in vivo: correlations with PEG molecular weight J Control Release. 2003 Jul 31;90(3):323-34

Passerini AG, Milsted A, Rittgers SE. (2003) Shear stress magnitude and directionality modulate growth factor gene expression in preconditioned vascular endothelial cells. Journal of Vascular Surgery 37:182-190.

Passerini AG, Polacek DC, Shi C, Francesco NM, Manduchi E, Grant GR, Pritchard WF, Powell S, Chang GY, Stoeckert CJ Jr., Davies PF. (2004) Coexisting pro-inflammatory and anti-oxidative endothelial transcription profiles in a disturbed flow region of the adult porcine aorta. Proc Natl Acad Sci U S A, 101(8):2482-2487.

Polacek DC*, Passerini AG*, Shi C, Francesco NM, Manduchi E, Grant GR, Powell S, Bischof H, Winkler H, Stoeckert CJ Jr., Davies PF. (2003) Fidelity and enhanced sensitivity of differential transcription profiles following linear amplification of nanogram amounts of endothelial mRNA. Physiological Genomics 13:147-156. (* shared first authorship)

Schiessel H. and H. Aranda-Espinoza, Electrostatically Induced Undulations of Lamellar DNA-Lipid Complexes. (2001) European Physical Journal E 5:499-502.

Schreiber, F. S., T.B. Deramaudt, T.B. Brunner, M.I. Boretti, K.J. Gooch, GH Enders, E.J. Bernhard, and Anil K. Rustgi. (2004) Successful growth and characterization of mouse pancreatic ductal epithelial cells: functional properties of the Ki-RASG12 oncogene. Gastroenterology, In press.

Snyder, S.E.; Shvets, A.B.; Pirkle, W.H. „Two-Component Chiral Phase Transfer Catalysis: Kinetic Resolution Through Intermediate Formation of Meisenheimer Complexes. Organic Letters 2004, In press.

Xian, W., Janmey, P.A. 2002. Dissecting the gelsolin-polyphosphoinositide interaction and engineering of a polyphosphoinositide-sensitive gelsolin C-terminal half protein. J Mol Biol. 322:755-71.

Xian, W., Tang, J.X., Janmey, P.A., Braunlin, W.H. 2000. The polyelectrolyte behavior of actin filaments: a 25Mg NMR study. Biochemistry. 38:7219-26.

Zahir, N., and Weaver, V.M. Death in the third dimension: apoptosis regulation and tissue architecture. Curr Opin Gen Dev. 14(1): 71-80, 2003.

Zahir, N., Lakins, J.N., Russel, A., Ming, W., Chatterjee, C., Rozenberg, G.I., Marinkovich, M.P., and Weaver, V.M. Autocrine laminin-5 ligates 6B4 integrin and activates RAC and NFkB to mediate anchorage-independent survival of mammary tumors. J Cell Biol. 163(6): 1397-407, 2003.

Kaufman, D.A., Albelda, S.M., Davies, P.F. 2004. Role of lateral cell-cell border location and extracellular/transmembrane domains in PECAM/CD31 mechanosensation in endothelial and REN cells. Biochem. Biophys. Res. Comm. In press.

2002-2003 (IME Core Research Program):

Adler, S.H., Chiffoleau, E, Xu, L., Dalton, N.M., Wells, A.D., Wolfe, M.S., Turka, L.A., Pear, W.S., Notch signaling augments T cell responsiveness by enhancing CD25 expression, J. Immunol., 171, 2896-2903: 2003.

Ahmed, F. A. Popescu, D.E. Discher, B.M. Discher. Block copolymer assemblies with crosslink stabilization: From single component monolayers to bilayer blends with PEO-PLA. Langmuir 19: 6505-6511 (2003)

Allenspach, E.J., Maillard, I., Aster, J.C., Pear, W.S., Notch and cancer. Cancer Biology and Therapy 1, 468-495, 2002.

Aranda-Espinoza, H. P. Carl, J-F. Letterier, P.A. Janmey, and D.E. Discher. Domain unfolding in Neurofilament sidearms: Effects of phosphorylation and ATP. FEBS Letters 531: 397-401 (2002).

B.M. Discher, H. Bermudez, D.A. Hammer, D.E. Discher, Y.-Y. Won, F.S. Bates. Cross-linked polymersome membranes: vesicles with broadly adjustable properties. J. Physical Chem. B 106: 2848-2854 (2002).

Bermudez, H., Arada-Espinoza, H. Hammer, D.A., Discher, D. E. 2003. Pore stability and dynamics in polymer membranes, Europhysics Letters 64: 550-556

Bermudez, H.,. Brannon, A. K., Hammer, D.A. Bates, F.S. Discher, D.E. 2002. Molecular Weight Dependence of Polymersome Membrane Elasticity and Stability Macromolecules 35:8203-8208.

Bhatia, S. K., Hammer, D. A. 2002. Influence of Receptor and Ligand Density on the Shear Threshold Effect for Carbohydrate-Coated Particles on L-selectin, Langmuir 18:5881-5885.

Bhatia, S. K., King, M.R.. Hammer D.A. 2003. The State Diagram for Cell-Adhesion Mediated by Two Receptors Biophys. J. 84: 2671-2690.

Bhatia, S.K., Swers, J., Camphausen, R. T., Wittrup, K. D., Hammer, D. A. 2003. Rolling adhesion kinematics of yeast engineered to express selectins, Biotechnol. Progress 19; 1033-1037.

Bissell, M.J., Radisky, D.C., Rizki, A., Weaver, V.M. and Petersen, O.M. The organizing principle: Microenvironmental influences in the normal and malignant breast. Differentiation. 70:537-546, 2002.

Bucki, R., Pastore, J.J., Giraud, F., Sulpice, J.C. and Janmey, P.A. 2003. Flavonoid inhibition of platelet procoagulant activity and phosphoinositide synthesis. J. Thromb. Haemost. 1:1820-8.

Byfield, J., Aranda-Aspinoza H., Romanenko, V. G., Rothblat, G. H. I. Levitan. 2003. Cholesterol depletion constraints mechanical deformation of aortic endothelial cells. Proc. IASTED International Conference on Biomechanics., pp 86-91.

Cebers, A., and Janmey, P. 2002. Shape instabilities in charged lipid domains. J Phys Chem B 106, 12351-12353.

Chatterjee S, Al-Mehdi AB, Levitan I, Stevens T, Fisher AB. 2003. Shear stress increases expression of a KATP channel in rat and bovine pulmonary vascular endothelial cells. Am J Physiol Cell Physiol. 285: C959-67.

Dahl, K.N. C. Westhoff, D.E. Discher. Fractional attachment of CD47 (IAP) to the erythrocyte cytoskeleton and visual co-localization with Rh protein complexes. Blood 101: 1194-1199 (2003).

Dahl, K.N., R. Parthasarthy, C. Westhoff, D.E. Discher. Protein 4.2 is critical to the CD47-membrane skeleton attachment in the human red cell. Blood (web-published 2003).

Dalhaimer, P. F.S. Bates, D.E. Discher. Single molecule visualization of stiffness-tunable, flow conforming worm micelles. Macromolecules 36: 6873-6877 (2003).

Dalhaimer, P. F.S. Bates, H. Aranda-Espinoza, D.E. Discher. Synthetic cell elements from block copolymers - Hydrodynamic Aspects. Comptes Rendus de d'Academie des Sciences - Serie IV Physique 4: 251-258 (2003).

Davies P.F., Helmke, B.P. 2002. The cytoskeleton under external fluid mechanical forces. Annals Biomedical Engineering 30: 1-13.

Davies, P.F. 2002. Multiple Signaling Pathways in Flow Mediated Endothelial Mechanotransduction: PYK-ing the right location Arterioscl. Thromb. Vasc. Biol. 22:1755-1757.

Davies, P.F., Polacek, D.C., Shi, C., Helmke, B.P. 2002. The Convergence of Hemodynamics, Genomics, and Endothelial Structure, in Studies of the Focal Origin of Atherosclerosis. Biorheology 39: 299-306.

Davies, P.F., Zilberberg, J., Helmke, B.P. 2003. Spatial Microstimuli in Endothelial Mechanosignaling Circ. Research 92:359-370.

Discher D.E., A. Eisenberg. Polymer Vesicles. (invited Review) Science 297: 967-973 (2002).

Discher, D.E., P. Photos, F. Ahmed, R. Parthasarathy, F.S. Bates. Polymersomes: A New Platform for Drug Targeting. (invited chapter) in Biomedical Aspects of Drug Targeting, editors: V.R. Muzykantov and V.P. Torchilin. Kluwer Academic Press (2002).

Doggett, T. A.,G. Girdhar, A. Lawshe, D. W. Schmidtke, I. J. Laurenzi, S. L. Diamond, T. G. Diacovo. Selectin-like Kinetics and Biomechanics Promote Rapid Platelet Adhesion in Flow: The GPIb-vWF Tether Bond. Biophys. J. 83, 194 (2002).

Doggett, T.A., G. Girdhar, A. Lawshe, J.L. Miller, I.J. Laurenzi, S.L. Diamond, T.G. Diacovo. Kinetic analysis of mutant GPIb alpha-vWF-A1 bonds reveal similarities between genetically distinct bleeding disorders. Blood Accepted (2003).

Eniola, A. O., Rodgers, S.D., Hammer, D.A.. 2002. Characterization of biodegradable drug delivery vehicles with the adhesive properties of leukocytes, Biomaterials 23:2167-2177.

Eniola, A. O., Willcox, J. Hammer, D.A. 2003. Interplay between Rolling and Firm Adhesion Elucidated with a Cell-Free System Engineered with Two Distinct Receptor-Ligand Pairs, Biophys. J. 85: 2720-2731.

Eniola, A. O.,. Hammer, D.A. 2003. Artificial polymeric cells for targeted drug delivery, J. Controlled Release 87:15-22.

Flanagan, L. A., Ju, Y. E., Marg, B., Osterfield, M., and Janmey, P. A. 2002. Neurite branching on deformable substrates. Neuroreport 13, 2411-5.

Goel, M. S. L. Diamond. Adhesion of normal erythrocytes to activated neutrophils, activated platelets, and fibrin polymerized from plasma at depressed venous shear rates. Blood. 100, 3739 (2002).

Goel, M., S. L. Diamond. Thrombosis. Encyclopedia of Biomaterials and Biomedical Engineering. Eds. G. E. Wnek, G. L. Bowlin. Marcel Dekker. In press. (2003).

Goel, M., S.L. Diamond. Neutrophil cathepsin G enhances prothrombinase and fibrin formation under flow by activating fibrinogen-adherent platelets. J. Biol. Chem. 278:9458 (2003).

Hategan, A. R. Law, S. Kahn, and D.E. Discher. Adhesively tensed erythrocyte membrane: lysis dynamics and AFM probing. Biophys. J 85: 2746-2759 (2003).

He, Y. Pear, W.S., 2003Notch signalling in B cells, Sem. Genes Dev.14, 135-142.

Helmke, B.P. Rosen, A.B., Davies, P.F. 2003. Mapping Mechanical Strain of an Endogenous Cytoskeletal Network in Living Endothelial Cells. Biophysical J. 84: 2691-2699.

Helmke, B.P., Davies, P.F. 2003. Imaging Live Cells under Mechanical Stress. In: Live Cell Imaging: A Laboratory Manual. Edited: Spector, D.L. and Goldman, R.L. Publ. Cold Spring Harbor Laboratory Press. In press

Janmey, P.A., Bucki, R. and Yin, H.L. 2003. Phosphoinositides and actin cytoskeletal rearrangement. In: Handbook of Cell Signalling

Ji, J., Y H. Jing, S. L. Diamond. Shear stress enhances nuclear localization of endothelial glucocorticoid receptor and expression from the GRE promoter. Circ. Res. 92:279 (2003).

JM. Abrahams, C Song, MS Grady, SL Diamond, RJ Levy. Endovascular Microcoil Gene Delivery Using Immobilized Anti-adenovirus Antibody for Vector Tethering. Stroke. 33, 1376 (2002).

King, M.R., Michael B. Kim, Ingrid H. Sarelius, and Daniel A. Hammer, (2003) Hydrodynamic interactions between rolling leukocytes in vivo, Microcirculation 10: 401-409.

Kiselar, J.G., Janmey, P.A., Almo, S.C. and Chance, M.R. 2003. Structural Analysis of Gelsolin Using Synchrotron Protein Footprinting. Mol. Cell Proteomics 2:1120-1132.

Kiselar JG, Janmey PA, Almo SC, Chance MR. 2003. Visualizing the Ca2+-dependent activation of gelsolin by using synchrotron footprinting. Proc Natl Acad Sci U S A 100(7):3942-7.

Laurenzi, I.J., S.L. Diamond. Kinetics of Reversible Aggregation and Gelation with Multiple Components. Phys. Rev. E. in press (2003).

Law, R. P. Carl, S. Harper, P. Dalhaimer, D.W. Speicher, D.E. Discher. Cooperativity in forced unfolding of tandem spectrin repeats. Biophys. J 84: 533-544 (2003).

Law, R., G. Liao, S. Harper, G. Yang, D.W. Speicher, D.E. Discher. Pathway shifts and thermal softening in temperature-coupled forced unfolding of spectrin domains. Biophys. J. 85: 3286-3293 (2003).

Liepina, I, Paul A. Janmey, P.A., Czaplewski, C., Liwo, A. 2003 Molecular dynamics study of the influence of calcium ions on the conformation of gelsolin S2 domain. J. Mol. Structure 630 309-313

Liepina, I., C. Czaplewski, et al. 2003. Molecular dynamics study of the binding of the 150-169 gelsolin fragment to phosphatidylinositol 4,5-biphosphate in water and to a lipid bilayer containing phosphatidylinositol 4,5-bisphosphate clusters. Biopolymers 71: 49-70

Lifshitz J, Friberg H, Neumar RW, Raghupathi R, Welsh FA, Janmey P, Saatman KE, Wieloch T, Grady MS, McIntosh TK. 2003. Structural and functional damage sustained by mitochondria after traumatic brain injury in the rat: evidence for differentially sensitive populations in the cortex and hippocampus. J Cereb Blood Flow Metab 23(2):219-31.

Ma, H., J. Zhu, M. Maronski, V.M.Y. Lee, M. Dichter, S.L. Diamond. Nonclassical nuclear localization signal peptides for high efficiency lipofection of primary neurons and neuronal cell lines. Neuroscience 111, 1 (2002).

Maillard, I. Pear, W.S., 2003. Notch and cancer: Best to avoid the ups and downs. Cancer Cell., 3, 203-205.

Maillard, I., He, Y., Pear, W.S., 2003.From the yolk sac to the spleen: New roles for notch in regulating hematopoiesis, Immunity 18, 587-9.

Michaud S, Wang L, Korde N, Bucki R, Randhawa P, Pastore K, Falet H, Hofmeister K, Kuuse R, Uibo R and others. 2002. Purification of salmonid thrombin and its potential as an alternative to mammalian thrombins in fibrin sealants. Thromb. Res. 107, 245-54.

Milam, V.T., Hiddessen, A. L. Crocker, J. C. Graves, D.J. Hammer, D. A.. 2003. DNA-driven assembly of bidisperse, micron-sized colloids Langmuir 19: 10317-10323.

Pear, W.S.. Radtke, F., Notch signaling in lymphopoiesis, Sem. Immunol.,15, 69-79, 2003.

Photos, P. B.M. Discher, L. Bacakova, F.S. Bates, D.E. Discher. Polymersomes in vivo: increased stealth with both PEG density and molecular weight. Journal of Controlled Release 90: 323-334 (2003).

Pierce, E. A., Q. Liu, O. Igoucheva, H.Ma, R. Omarrudin, S. L. Diamond, K. Yoon. Oligonucleotide-directed single base DNA alterations in mouse embryonic stem cells. Gene Therapy. 10:24 (2003).

Polacek, D.C., Passerini, A., Shi, C., Francesco, N.M., Manduchi, E., Grant, G., Powell, S.J., Bischof, H., Winkler, H., Stoeckert, C., Davies, P.F. 2003. Fidelity and enhanced sensitivity of differential transcription profiles following linear amplification of nanogram amounts of endothelial mRNA. Physiological Genomics 13:147-156.

Reinhart-King, C.A., Dembo, M., Hammer, D.A. 2003. Endothelial Cell Traction Forces on RGD-Derivatized Polyacrylamide Substrata Langmuir 19:1573-1579.

Rizzo V., Morton C., DePaola, N., Schnitzer, J., and Davies, P.F. 2003. Recruitment of endothelial caveolae into mechanotransduction pathways by flow-conditioning in vitro. Am. J. Physiol. 285:H1720-9.

Romanenko VG, Rothblat GH, Levitan I. 2002. Modulation of endothelial inward-rectifier K+ current by optical isomers of cholesterol. Biophys J. 83: 3211-22.

Romanenko, V., Davies, P.F., Levitan, I. 2002 Dual effect of fluid shear stress on volume regulated anion current in bovine aortic endothelial cells. Am. J. Physiol. 282: C708-718.

Russell, A., Fincher, E.F., Millman, L., Smith, R., Vela, V., Weaver, V.M. Marinkovich, P.M. a6/ß4-integrin coordinates EGF-induced chemotaxis inkeratinocytes. J. Cell Sci. 116:3543-3556, 2003.

Santore, M.M. D.E. Discher, F.S. Bates, Y-Y. Won, and D.A. Hammer. The effect of surfactant on unilamellar polymeric vesicles: altered membrane properties and stability in the limit of weak surfactant partitioning. Langmuir 18: 7299-7308 (2002).

Sun A.C, Levitan I. 2003. Osmotic stress alters the intracellular distribution of non-erythroidal spectrin (fodrin) in bovine aortic endothelial cells. J. Membr. Biol. 192: 9-17.

Tang JX, Janmey PA, Lyubartsev A, Nordenskiold L. 2002. Metal Ion-Induced Lateral Aggregation of Filamentous Viruses fd and M13. Biophys J 83: 566-81.

Tessier, F. D.H. Boal, D.E. Discher. Spring networks with C4 symmetry in two dimensions. Physical Review E 67: 011903/pg.1-10 (2003).

Thomas G.H., D.E. Discher. Spectrin elasticity in red blood cells. (invited chapter) in Elastomeric Proteins, editors: P.R. Shewry, A.S. Tatham, A. Bailey. Cambridge Univ. Press. (2003).

Unger, M., Weaver, V.M. The tissue microenvironment as an epigenetic tumor suppressor. Methods Mol Biol 223:315-347, 2003.

Wagner, O.I., Lifshitz, J., Janmey, P.A., Linden, M., McIntosh, T.K. and Leterrier, J.F. 2003. Mechanisms of mitochondria-neurofilament interactions. J. Neurosci. 23:9046-58.

Weaver, V.M., Lelievre, S., Lakins, J.N., Chrenek, M., J.N., Jones, J., Giancotti, F., Werb, Z., and Bissell, M.J. ß4-integrin-dependent formation of polarized three-dimensional architecture confers resistance to apoptosis in normal and malignant mammary epithelium. Cancer Cell 2:205-216, 2002.

Weiner DJ, Bucki R, Janmey PA. 2003. The Antimicrobial Activity of the Cathelicidin LL37 Is Inhibited by F-actin Bundles and Restored by Gelsolin. Am J Respir Cell Mol Biol 28:738-45.

Weng, A.P., Nam, Y., Wolfe, M.S., Pear, W.S., Griffen, J.D., Blacklow, S.C., and Aster, J.C., Growth suppression of pre-T acute lymphoblastic leukemia cells through targeting of nuclear Notch1, Mol. Cell. Biol., 23, 655-664: 2003.

Wertheim JA, Forsythe K, Hammer D, Boettiger D, Pear WS. 2003. Localization of BCR-ABL to F-actin regulates cell adhesion but does not attenuate CML development, Blood 102: 2220-2228.

Wertheim, J.A. Forsythe, K., Druker, B.J., Hammer, D.A., Boettiger, D., Pear, W.S. 2002. BCR-ABL induced adhesion defects are tyrosine kinase independent. Blood 99: 4122-4130.

Wong, G. C. L., Lijn, A., Tang, J. X., Li, Y., Janmey, P. and Safinya, C. R. 2003. Lamellar Phase of Stacked Two-Dimensional Rafts of Actin Filaments. Phys. Rev. Lett. 91, 018103.

Xian W, janmey P. 2002. Dissecting the Gelsolin-Polyphosphoinositide Interaction and Engineering of a Polyphosphoinositide-sensitive Gelsolin C-terminal Half Protein. J Mol Biol: 322:755-71.

Yin H, Janmey P. 2002. Phosphoinositide Regulation of the Actin Cytoskeleton. Ann Rev Physiol. 65:761-89..

Zahir N., Yeung, T., Ming, W., Janmey, P.A. Weaver, V.M. Peering from the outside in: viscoelastic properties of the extracellular matrix dictate spatial organization and apoptosis resistance in mammary epithelial cells. IEEE. 10:430-431, 2002.

Zhang J. C.L., Helmke B.P., Shum A., Yu W. W.,. Lu M. M, Davies P. F., Parmacek M.S.. 2002. SM22: A Novel Cytoskeletal Protein Expressed in a Cell Lineage-Restricted Pattern. Mechanisms of Development 115:161-166.

Zhang, Y. Eniola, A. O., Graves, D. J., Hammer, D. A.. 2003. Specific Adhesion of Micron-Sized Colloids to Surfaces Mediated by Hybridizing DNA Chains, Langmuir 19: 6905-6911.