Darren Taichman, M.D., Ph.D.

Assistant Professor of Medicine
Director, Medical Intensive Care Unit
Penn- Presbyterian Medical Center
Associate Director, Pulmonary Vascular Disease Program
Hospital of the University of Pennsylvania

University of Pennsylvania Medical Center
Pulmonary, Allergy & Critical Care Division
Suite 441 PHI Building
Presbyterian Medical Center
39th and Market Street
Philadelphia, PA 19104
tel.: (215) 662-8585
fax: (215) 243-4643
email: darren.taichman@uphs.upenn.edu

Education:

MD, PhD: University of Pennsylvania School of Medicine

Residency: Beth Israel Hospital, Harvard Medical School

Fellowship: Hospital of the University of Pennsylvania

Dr. Taichman's clinical and research interests are in pulmonary vascular disease and critical care medicine. He is the Associate Director of Penn's Pulmonary Vascular Disease Program, a multi-disciplinary program specializing in the diagnosis and treatment of pulmonary arterial hypertension as well as acute and chronic thromboembolic disease. Dr. Taichman’s research focuses on understanding both the basic biology and clinical manifestations of pulmonary vascular diseases. Dr. Taichman is also the Clinical Director of the Penn-CMREF Center for Pulmonary Hypertension Research, part of a national, multi-centered initiative collecting biologic samples to foster research in this field. Among his clinical investigations are studies of neurocognitive function and deficits, and determinants of quality of life in patients with pulmonary arterial hypertension. Dr. Taichman’s studies also involve the establishment of a database and blood repository for the study of protein expression patterns, genetic and other risk factors influencing the development of pulmonary hypertension and response to therapy. His basic science investigations have also focused on the molecular mechanisms controlling pulmonary vascular development.

Dr. Taichman is also a member of the Education and Publications Division of the American College of Physicians. Here, his work includes the development of educational programs and services for physicians practicing internal medicine and its subspecialties.

Dr. Taichman is Board Certified in Internal Medicine, Pulmonary Diseases and Critical Care Medicine

Pulmonary Vascular Disease. J. Mandel and D.B. Taichman (eds.). Elsevier Science. Philadelphia, PA 2006.

White DB, Curtis JR, Wolf L, Prendergast TJ, Taichman DB, Kuniyoshi G, Acerra F, Lo B, Luce JM. Life Support Decisions for Incapacitated Patients Without Surrogates: Who Decides? Annals of Internal Medicine. 2007 Jul 3;147(1):34-40

Delisser, H. M., Helmke, B. P., Cao, G., Egan, P.M., Taichman, D., Fehrenbach, M., Zaman, A., Cui, Z., Mohan, G. S., Baldwin, H. S., Davies, P. F., Savani, R. C.: Loss of PECAM-1 Function Impairs Alveolarization. J Biol Chem. 281(13): 8724-31, 2006.

Taichman, DB, Shin, J., Hud, L., Archer-Chicko, C., Kaplan, S., Sager, JS, Gallop, R., Christie, J., Hansen-Flaschen, J. and Palevsky, HI. : Health-related quality of life in patients with pulmonary arterial hypertension Respir Res Vol. 6: 92, 2005.

Taichman, DB, Christie, J., Biester, R., Mortensen, J., White, J., Kaplan, S., Hansen-Flaschen, J., Palevsky, H.I., Elliott, C.G., and Hopkins, R.O.: Validation of a brief telephone battery for neurocognitive assessment of patients with pulmonary arterial hypertension. Respir Res 6(1), 39 2005.

Kawut SM, Taichman DB, Archer-Chicko C, Palevsky HI, Kimmel SE: Hemodynamics and survival in pulmonary arterial hypertension related to systemic sclerosis. Chest. 123: 344-350, 2003.

Taichman DB, Schachtner SK, Puri M, Williams P, Bernstein A, Baldwin HS: A unique pattern of Tie1 on the developing pulmonary vasculature. Exp Lung Res. 29: 113-122, 2003.

Taichman DB, Loomes K, Schachtner SK, Vu, C, Williams P, Oakley R, Baldwin HS. Jagged1 and Notch 1 on the developing pulmonary vasculature. Dev Dyn. 225: 166-75, 2002.