James C. Lee, M.D.

Assistant Professor of Medicine

Pulmonary, Allergy & Critical Care Division
826 West Gates Building
3400 Spruce Street
Philadelphia, PA 19104
tel: (215) 614-0986
fax: (215) 614-0518
email: james.lee@uphs.upnn.edu

Education:

• MD: University of Pennsylvania School of Medicine
• Residency: Johns Hopkins Hospital, Baltimore, MD
• Fellowship: Hospital of the University of Pennsylvania 

Dr. Lee is a member of the Advanced Lung Disease Section within the Division and is a full time clinician in the Penn Lung Transplant Program. He has clinical and research interests in lung transplantation and improving early outcomes, specifically focusing on primary graft dysfunction resulting from oxidative stress. He is currently conducting research investigating the use of dietary antioxidants in patients awaiting lung transplantation to potentially improve immediate outcomes.

Representative Publications:

Lee JC, Christie J: Primary Graft Dysfunction. Proceedings of the American Thoracic Society. Garrity ER, Leff A, Orens J (eds.). 6(1): 39-46, January 2009.

Lingaraju R, Pochettino A, Blumenthal NP, Mendez J, Lee JC, Christie JD, Kotloff RM, Ahya VN, Hadjiliadis D: Lung Transplant Outcomes in White and African American Recipients: Special Focus on Acute and Chronic Rejection. Journal of Heart and Lung Transplantation. 28(1): 8-13, January 2009.

Lee JC, Krochak R, Blouin A, Kanterakis S, Chatterjee S, Arguiri E, Vachani A, Solomides CC, Cengel KA, Christofidou-Solomidou M: Dietary Flaxseed Prevents Radiation-Induced Oxidative Lung Damage, Inflammation and Fibrosis in a Mouse Model of Thoracic Radiation Injury. Cancer Biology and Therapy.  8(1): 47-53, January 2009.

Lee JC, Bhora F, Sun J, Cheng G, Arguiri E, Solomides CC, Chatterjee S, Christofidou-Solomidou M: Dietary Flaxseed Enhances Antioxidant Defenses and is Protective in a Mouse Model of Lung Ischemia/Reperfusion Injury. American Journal of Physiology: Lung Cellular and Molecular Physiology. 294(2): L255-65, February 2008. Machtay M, Scherpereel A, Santiago J, Lee JC, McDonough J, Kinniry P, Arguiri E, Shuvaev VV, Sun J, Cengel K, Solomides CC, Christofidou-Solomidou M: Systemic Polyethylene Glycol-Modified (PEGylated) Superoxide Dismutase and Catalase Mixture Attenuates Radiation Pulmonary Fibrosis in the C57/bl6 Mouse. Radiotherapy and Oncology 81(2): 196-205, October 2006.