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Samuel T. Kuna, M.D.

Associate Professor of Medicine
Chief, Pulmonary, Critical Care & Sleep Section
Philadelphia Veterans Affairs Medical Center

University of Pennsylvania Medical Center
Pulmonary, Allergy, & Critical Care Division
Philadelphia Veterans Affairs Medical Center
3900 Woodland Avenues
Philadelphia, PA 19104
tel.: (215) 823-4400
fax: (215) 823-5876
email: skuna@mail.med.upenn.edu
Samuel.Kuna@va.gov

Education:

  • MD: Columbia College of Physicians and Surgeons
  • Residency: Hospital of the University of Pennsylvania
  • Fellowship: Hospital of the University of Pennsylvania

Dr. Kuna is Associate Professor of Medicine at the University of Pennsylvania and Chief of the Pulmonary, Critical Care and Sleep Section at the Philadelphia Veterans Affairs Medical Center. Dr. Kuna joined the Division in September 1999 and is a member of the Center for Sleep and Respiratory Neurobiology. Dr. Kuna's primary academic goal is to develop an outstanding research program based in his clinical research in the pathogenesis and clinical management of obstructive sleep apnea.

Dr. Kuna graduated summa cum laude from Muhlenberg College where he was elected to Phi Beta Kappa, and obtained his medical degree from Columbia College of Physicians and Surgeons were he was elected to Alpha Omega Alpha. Dr. Kuna completed his Internal Medicine internship and residency, and pulmonary fellowship at the University of Pennsylvania. Following his fellowship, Dr. Kuna joined the faculty at the University of Pennsylvania as Assistant Professor. During this period, Dr. Kuna developed a strong interest in the control the breathing. Dr. Kuna was a faculty member at the University of Texas Medical Branch from 1982-1999. While at UTMB, his primary clinical and research interest became focused on the pathogenesis of obstructive sleep apnea and upper airway muscle physiology. He served as medical director of the UTMB Sleep Laboratory from 1984-1999.

Dr. Kuna’s current primary research concerns the ambulatory management of patients with sleep apnea. He is PI on a VA funded project VSATT (Veterans Sleep Apnea Treatment Trial) comparing clinical outcomes and cost effectiveness of unattended portable monitor testing versus standard in-laboratory testing in patients with sleep apnea. He is the PI for the Penn clinical site in the NIH funded Sleep AHEAD (Action for Health in Diabetes) study, a randomized controlled trial examining the effect of weight loss on sleep disordered breathing in obese type 2 diabetics. Dr. Kuna also directs the centralized scoring program at Penn for analysis of sleep studies performed in VSATT, Sleep AHEAD and CATNAP (CPAP Apnea Treatment North American Program), the latter being an NIH funded randomized controlled trial to determine the effects of CPAP treatment in patients with milder obstructive sleep apnea. Dr. Kuna is collaborating with Dr. Allan Pack on one of the projects in the Center for Sleep and Respiratory Neurobiology’s SCOR grant research project to determine the heritability of sleep homeostasis. This research is comparing responses to sleep deprivation in monozygotic and dizygotic twins. Dr. Kuna continues to pursue his interest in upper airway mechanics through his collaboration with Dr. Michael Brennick, whose NIH funded research is investigating the effects of obesity on pharyngeal airway mechanics using sophisticated MRI techniques in the obese Zucker rat model. Since 1999, Dr. Kuna has published over 15 peer review papers including 6 articles in the leading respiratory journal and an article on obstructive sleep apnea in JAMA’s Clinical Crossroads series. In addition, he co-authored the chapter on the anatomy and physiology of upper airway obstruction in the last two editions of Principles and Practice of Sleep Medicine, the leading textbook of that medical specialty.

Dr. Kuna is past president of the Texas Thoracic Society and has served on the Research Committee, Board of Directors and Executive Board of Directors of the American Lung Association of Texas. He received the Chairman's Award from the American Lung Association of Texas in 1993. Dr. Kuna has been active in the American Thoracic Society and from 1997-1999 was chair of that society's Respiratory Neurobiology and Sleep Assembly as well as a member of the American Thoracic Society's Board of Directors. He is currently a member of the Fellowship Training Committee of the American Thoracic Society. He is a past recipient of a Research Career Development Award and is past chair of the NIH Respiratory Applied Physiology Study Section. He was a member of the editorial board of the Journal of Applied Physiology from 1994-1999 and is currently an associate editor of the journal SLEEP. He has lectured widely at symposia, post-graduate courses and seminars on the topic of respiratory disorders during sleep and in 2002 organized the National VA Sleep Research Conference held in Philadelphia.

Dr. Kuna's clinical activities are performed at the Philadelphia Veterans Affairs Medical Center where he serves as medical director of the VISN 4 Eastern Regional Sleep Center. He attends on the Pulmonary Consult Service and Medical Intensive Care Unit. In addition he staffs outpatient sleep clinics. In these venues, Dr. Kuna supervises and teaches medical students, house officers and fellows. Dr. Kuna received the 2003 Mark Wolcott Award for Excellence in Clinical Care Delivery, a national award given yearly by the Veterans Health Administration to a physician who has made outstanding contributions to clinical care. Dr. Kuna is listed in the “Best Doctors in America: Eastern Region” database.

Representative publications:

Foster GD, Sanders MH, Millman R. Zammit G, Borradaile KE, Newman AB, Wadden TA, Kelley D, Wing RR, Pi Sunyer FX, Darcey V, Kuna ST, and the Sleep AHEAD Research Group: Obstructive sleep apnea among obese patients with type 2 diabetes. Diabetes Care 32(6): 1017-1019, 2009.

Castriotta RJ, Atanasov S, Wilde MC, Masel BE, Lai JM, Kuna ST: Treatment of sleep disorders after traumatic brain injury. J Clin Sleep Med  5(2): 137-44, 2009.

Platt AB, Field SH, Asch DA, Chen Z, Patel NP, Gupta R, Roche DF, Gurubhagavatula I, Christie JD, Kuna ST: Neighborhood of residence is associated with daily adherence to CPAP therapy. Sleep 32(6): 799-806, 2009.

Foster GD, Borradaile KE, Sanders MH, Millman RP, Zammit G, Newman AB, Wadden TA, Kelley D, Wing RR, Pi-Sunyer FX, Reboussin D, Kuna ST, and The Sleep AHEAD Group of the Look AHEAD Research Group: A randomized study on the effect of weight loss on obstructive sleep apnea among patients with type 2 diabetes: The Sleep AHEAD study. Arch Int Med in press

revised 7/09



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