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Marfan Syndrome and Related Connective Tissue Disorders

Marfan syndrome affects the body's connective tissue. The primary purpose of connective tissue is to hold the body together and provide a framework for growth and development. It provides the strength and support to tendons, cartilage, heart valves and blood vessels, as well as many other parts of the body. Marfan syndrome weakens connective tissue and can affect many body parts such as the bones, eyes, heart, blood vessels, nervous system, skin and lungs.

Penn is dedicated to the comprehensive evaluation and management of older children and adults with a known or suspected diagnoses of Marfan syndrome or related condition such as MASS phenotype, familial ectopia lentis (dislocated lenses) or familial aortic aneurysm.

We provide coordinated multidisciplinary care including diagnosis, genetic testing, education, genetic counseling, management and support. Our physicians have special experience in treating patients with Marfan syndrome and related disorders.