Penn Medicine Neuroscience Center

About the Center

Funding Opportunities and Grants

A major goal of the Penn Medicine Neuroscience Center (PMNC) is to promote integrated basic, translational and clinical research efforts – with the ultimate goal of improving patient care.


FY14 Pilot Innovative Research Projects - Call for Proposals

The Penn Medicine Neuroscience Center (PMNC) announces new funding for Penn faculty whose work falls within the broad category of the neurosciences.  This funding will be offered over the course of the 2013-2014 (FY14) academic year.

Click here to view the Call for Proposals for Innovative Pilot Research Projects. A primary goal of the Penn PMNC is to promote the initiation of projects that provide novel and creative approaches towards addressing major problems in neuroscience.  The PMNC is pleased to offer grant funding to Penn faculty in support of this mission.


Previously Awarded Projects

In 2006, 2007, 2011 and 2012, the PMNC invited proposals from full-time faculty for the support of pilot collaborative projects involving co-investigators from two or more departments in the Perelman School of Medicine (PSOM), or from one PSOM department and one in another school at Penn.

The purpose of this program is to assist Penn neuroscience faculty in generating preliminary data that may serve as the basis for seeking longer-term funding from federal, foundation or corporate sources.


FY13 Pilot Innovative Research Projects

The PMNC funded 8 collaborative research projects for FY13. The innovative research project titles are listed below:

  • Labeling Newly Phosphorylated Proteins in Response to Signal Pathway Activation
  • Defining the role of TRIM proteins in protection against neurodegeneration
  • Imaging learning dependent neuronal activity patterns in behaving animals
  • Epigenetic Control of Experience-dependent Neural Plasticity
  • Prefrontal computations for reward-biased perceptual decisions
  • Using RNA-Seq To Relate Odorant Receptor, Axonal Guidance Receptor, And Transcription Factor Expression Patterns In Single Isolated Olfactory Sensory Neurons
  • Functional Connectivity and Persistent Dysfunction in Mild Traumatic Brain Injury
  • Optical Measurement of Absolute Membrane Potentials


FY12 Pilot Collaborative Research Projects

The PMNC funded 10 collaborative research projects in the total amount of $500,000 for FY12. The investigators collaborating on the 10 funded projects represent 18 different departments and 5 Penn schools. The currently funded collaborative research project titles are below:

  • Development of a novel MRI biomarker to assess brain white matter
    integrity in traumatic brain injury
  • The ReCoUPS Pilot: Recovering Concussion Update on Progression of
    Symptoms
  • The role of cortico-cortical connections of the mammalian sensory cortex
    in information processing
  • Novel FLIM based approach to study HSV-1 entry into neurons
  • Model Investigation of mTOR Pathway Modulation in Autism and Epilepsy
  • Common and Divergent Mechanisms of Anhedonia Across Psychiatric
    Disorders
  • Light-induced gene activation in C. elegans
  • Elucidating the link between stress and tauopathies such as Alzheimer’s
    disease
  • Watching the single neuron in action: monitoring metabolic responses at
    a single cell level
  • Investigation of Tau-Interacting Aminothienopyridazines


Click here to learn more about previously awarded projects.