Resident Physician, PGY-7

Department of Neurosurgery, Silverstein 3
The Hospital of the University of Pennsylvania
3400 Spruce Street
Philadelphia, PA 19104
(215) 662-3487
neil.malhotra@uphs.upenn.edu

Biographical Sketch

Dr. Malhotra received his undergraduate degree with high distinction from the University of Virginia in 1997 and his medical degree from the University of Virginia, where he was the J. Collins Scholar. He is currently serving as a resident in the Department of Neurosurgery at the Hospital of the University of Pennsylvania. Dr. Malhotra's primary research interests focus on restorative approaches to treat degenerative disc disease. More specifically, his interests focus on a tissue engineering approach to the development of treatments to restore native tissue mechanics of the spine while delivering theraputic agents and supporting tissue regeneration.

In The Press

Neil Malhotra, MD and NP Solutions win the University of Pennsylvania Wharton School's business plan competition:

• CNN
• Forbes

Publications

Cloyd, J., Malhotra, N.R., Weng, L., Chen, W., Mauck, R.L., Elliott, D. Modulus and Poisson’s Ratio in Unconfined Compression for Human Nucleus Pulposus and Potential Implants to Treat Disc Degeration. In Press: European Spine Journal

Boockvar JA, Stiefel M, Malhotra NR, Dolinskas C, Dwyer-Joyce C, LeRoux PD. Dural Cavernous angioma of the posterior sagittal sinus: case report. Surgical Neurology 63: 178-181, 2005

Gaston B. Ratjen F. Vaughan JW. Malhotra NR. Canady RG. Snyder AH. Hunt JF. Gaertig S. Goldberg JB. Nitrogen redox balance in the cystic fibrosis airway: effects of antipseudomonal therapy. [Journal Article] American Journal of Respiratory & Critical Care Medicine. 165(3):387-90, 2002 Feb 1.

Hunt JF. Erwin E. Palmer L. Vaughan J. Malhotra N. Platts-Mills TA. Gaston B. Expression and activity of pH-regulatory glutaminase in the human airway epithelium. American Journal of Respiratory & Critical Care Medicine. 165(1):101-7, 2002 Jan 1.

Hunt JF. Fang K. Malik R. Snyder A. Malhotra N. Platts-Mills TA. Gaston B. Endogenous airway acidification. Implications for asthma pathophysiology. American Journal of Respiratory & Critical Care Medicine. 161(3 Pt 1):694-9, 2000 Mar.

Presentations

International

Malhotra, NR, Beckstein, J., Cloyd, J., Chen, W., Elliott, D. An In-situ Polymerizing Hydrogel to Mimic Nucleus Pulposus Ex Vivo and In Vitro. 2007 The International Meeting on Advanced Spinal Techniques (IMAST), Paradise Island, Bahamas. July 14, 2007

Malhotra, N.R., Beckstein, J., Cloyd, J., Chen, W., Elliott, D. A Novel Injectable Nucleus Pulposus Implant Restores Range of Motion. Seventh Annual Meeting for the International Spinal Arthroplasty Society Meeting (SAS7), Berlin, Germany. May 01, 2007

Malhotra, N.R., Beckstein, J., Cloyd, J., Chen, W., Elliott, D. Restoration of Nucleus Pulposus Functional Mechanics via a Novel Injectable Implant. 2007 Annual Meeting for the International Society for the Study off The Lumbar Spine (ISSLS), Hong Kong China. June 10, 2007

National

Cloyd, J., Malhotra, N.R., Weng, L., Chen, W., Mauck, R.L., Elliott, D. Defining Unconfined Compression Modulus and Poisson's Ratio for Human Nuceus Pulposus & Potential Nucleus Replacement Materials. Annual Meeting of the Orthopedic Research Society, San Diego CA. February 11, 2007

Chen, I., Malhotra, N.R., Levine, J., LeRoux, P. Barbiturate Infusion and Cerebral Oxygenation. 2006 Annual Meeting of the Congress of Neurological Surgeons, Chicago IL. October 7, 2006

Stiefel MF, Spiotta A, Gracias V, Heuer G, Danish S, Magge SN, Malhotra N.R., Jackson E, Zaghloul K, Maloney-Wilensky E, Grady MS, Leroux P. Brain tissue oxygen-guided management reduces mortality in traumatic brain injury. Neurocritical Care Society meeting, Scottsdale, AZ. February 25, 2005.

Malhotra, N.R., Huang, J., Schuster, J. Hemorrhage into synovial cysts as a cause of acute radicular symptoms. AANS/CNS Section on Disorders of the Spine and Peripheral Nerves 2005 Annual Meeting, Phoenix, AZ. March 12, 2005

Ramakrishna, R., Malhotra, N.R., Burnett, M., Maloney-Wilenksy, E., Schuster S. Survival in patients with Glioblastoma Multiforme as a Function of Post-Operative Ambulation Status. 2006 Annual Meeting of the American Association of Neurological Surgeons, San Francisco CA. April 15, 2006

Local

Malhotra, N.R., Cloyd, J., Beckstein, J., Chen, W., Elliott, D. Reversing Disc Degeneration via Restoration of Nucleus Pulposus Functional Mechanics. Pan Philadelphia Neuroscience Meeting, Philadelphia PA. January 5, 2007

Malhotra, N.R. A Novel Nucleus Pulposus Supporting Agent To Reverse Decline in Mechanical Function of the Intervertebral Disc. University of Pennsylvania Neurosurgery Grand Rounds, Philadelphia PA. October 5, 2006

Malhotra, N.R. An Expanding Role for Phenobarbitol Infusion in the Setting of Intractable ICP Elevation? University of Pennsylvania Neurosurgery Grand Rounds, Philadelphia PA. September 7, 2006

Chen, I., Malhotra, N.R., Levine, J., LeRoux, P. Effect of Barbiturate Infusion on Cerebral Oxygenation. 2006 Annual Meeting of the Pennsylvania Neurosurgical Society, Hershey PA. July15, 2006

Malhotra, N.R., Cloyd, J., Beckstein, J., Chen, W., Elliott, D. Injectable Hydrogels to Support Nucleus Pulposus Function: The Concept. 2006 Annual Meeting of the Pennsylvania Neurosurgical Society, Hershey PA. July15, 2006

Malhotra, N.R., Spiotta, A., Jackson, E., Maloney-Wilensky E, Leroux P. Effects of DVT prophylaxis of Cerebral Oxygenation. 2004 Annual Meeting of the Pennsylvania Neurosurgical Society, Hershey PA. August 20, 2004

Abstracts

Malhotra, N.R., Beckstein, J., Cloyd, J., Chen, W., Elliott, D. Restoration of Nucleus Pulposus Functional Mechanics via a Novel Injectable Implant. 2006 Annual Meeting for the International Society for the Study off The Lumbar Spine (ISSLS). In press

Cloyd, J., Malhotra, N.R., Chen, W., Elliott, D. Defining Unconfined Compression Modulus and Poisson's Ratio for Human Nuceus Pulposus & Potential Nucleus Replacement Materials. Proceeds of the 2007 Annual Meeting of the Orthopedic Research Society. In press

Malhotra, N.R., Cloyd, J., Beckstein, J., Chen, W., Elliott, D. A Novel Injectable Nucleus Pulposus Implant Restores Range of Motion. Proceeds of the 2007 Annual Meeting of The Spine Arthroplasty Socety. In Press

Malhotra, N.R., Beckstein, J., Cloyd, J., Chen, W., Elliott, D. In-situ Polymerizing Hydrogels to Restore Range of Motion in the Degenerate Disc. Proceeds of the 2007 International Meeting on Advanced Spinal Techniques (IMAST). Submitted

Malhotra, N.R., Beckstein, J., Cloyd, J., Chen, W., Elliott, D. In-situ Polymerizing Hydrogels to Restore Range of Motion in the Degenerate Disc. Proceeds of the Scoliosis Research Society Meeting (SRS). Submitted

Ramakrishna, R., Malhotra, N.R., Burnett, M., Maloney-Wilenksy, E., Schuster S. Survival in patients with Glioblastoma Multiforme as a Function of Post-Operative Ambulation Status. Proceeds of the 2006 Annual Meeting of the American Association of Neurological Surgeons. April 2006

Malhotra, N.R., Huang, J., Schuster, J. Hemorrhage into synovial cysts as a cause of acute radicular symptoms. Proceeds of the Annual Meeting of the AANS/CNS Section on disorders of the Spine and Peripheral Nerves. March 2005

Malhotra, N.R., LeRoux, P. Effects of DVT prophylaxis of Cerebral Oxygenation. Proceeds of the 2004 Annual Meeting of the Pennsylvania Neurosurgical Society. August 2004