Department of Neurosurgery

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Neurosurgery Clinical Research Division

The Neurosurgery Clinical Research Division (NCRD) is dedicated to the development of research projects that focus on the neurosurgical interventions for surgical disorders of the nervous system and present and publish the results of those trials at completion.

The NCRD is committed to conducting clinical research that protects the rights of human subjects through adherence to the standard operating procedures for good clinical practice established at the University of Pennsylvania to ensure the institutional culture of research excellence.

Current Clinical Trials

Dystonia

  • Humanitarian Device Exemption (HDE) for Medtronic Activa® Dystonia Therapy (HDE# H0200007)

  • Subthalamic Nucleus and Globus Pallidus Deep Brain Stimulation in Dystionia: A Prospective, Double-Blind Study of Safety and Efficacy (HDE# H0200007)

Brain Tumors

  • Phase V GliaSite® Radiation Therapy System (RTS) Registry Protocol for the Treatment of Resectable Malignant Brain Tumors

  • Phase III Randomized Evaluation of Convection Enhanced Delivery of IL13-PE38QQR Compared to Gliadel® Wafer with Survival Endpoint in Glioblastoma Multiforme Patients at First Recurrence

  • NABTT# 9903: Interstitial Infusion of IL13-PE38QQR Cytotoxin in Recurrent Malignant Glioma: Phase I/II Study

 

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