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January 26, 2015

Penn Study Reveals Possible Therapeutic Target for Common, But Mysterious Brain Blood Vessel Disorder

Tens of millions of people around the world have abnormal, leak-prone sproutings of blood vessels in the brain called cerebral cavernous malformations (CCMs). These abnormal growths can lead to seizures, strokes, hemorrhages, and other serious conditions, yet their precise molecular cause has never been determined. Now, cardiovascular scientists at the Perelman School of Medicine at the University of Pennsylvania have studied this pathway in heart development to discover an important set of molecular signals, triggered by CCM-linked gene defects, that potentially could be targeted to treat the disorder. Read more ...

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Penn Medicine Magazine

Fall 2014

Current Issue: Fall 2014

Scientists and clinicians at Penn Medicine and elsewhere have been expanding our knowledge of the harm that football and some other sports can do to the brain and coming up with ways to detect and treat brain injuries sooner. Concussion has drawn the most attention, but a newer focus is chronic traumatic encephalopathy. In addition, Penn researchers are working on ways to detect and treat traumatic brain injuries caused by battlefield blast waves.

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