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aPRIL 8, 2014

Symposium on Cellular Reprogramming to be Held at Penn Medicine

PHILADELPHIA — The University of Pennsylvania’s Institute for Regenerative Medicine will host a symposium on Friday, April 11, 2014 to detail the progress researchers are making toward reprogramming human cells to treat a variety of diseases.

In addition to talks on the basic science of regenerative medicine, Nobel laureate John Gurdon will present the keynote address entitled, “Past, Present and Future Prospects for Nuclear Reprogramming by Amphibian Eggs and Oocytes,and New York Times reporter Nicholas Wade will speak about “Regenerative Medicine: Promises and Perils.”

When: Friday, April 11, 2014, 8:30am – 5:00pm

Where:  BRB Auditorium, 421 Curie Blvd, Philadelphia, PA 19104

What: Agenda and other details can be found on the IRM web site.

Symposium schedule:

8:30 Introduction and Welcome
J. Larry Jameson, MD, PhD
Executive Vice-President, University of Pennsylvania for the Health System
Dean, Perelman School of Medicine
John Gearhart, PhD
Director, Institute for Regenerative Medicine

Keynote:  Past, Present and Future Prospects for Nuclear Reprogramming by Amphibian Eggs and Oocytes
John Gurdon, FRS, FMedSci
2012 Nobel Laureate in Physiology and Medicine
Wellcome Trust/Cancer Research UK Gurdon Institute
The Henry Wellcome Building of cancer and Developmental Biology

9:45 Progress Towards Instructing Our Cells for Therapies
John Gearhart, PhD
10:00 BREAK
10:15 Session 1: Pluripotency
Chair: Jon Epstein, MD
Chair, Department of Cell and Developmental Biology
10:20 Dissecting the Steps of Reprogramming to Pluripotency
Kathrin Plath, PhD
Associate Professor, Department of Biological Chemistry
University of California – Los Angeles
11:00 Mechanisms of Cellular Programming and Reprogramming
Ken Zaret, PhD
Professor, Cell and Developmental Biology
Associate Director, Institute for Regenerative Medicine
11:35 Regenerative Medicine: Promises and Perils
Nicholas Wade
Science Journalist and Author
New York Times
1:00 Session 2: Developmental Biology
Chair: Chris Lengner, PhD
Assistant Professor
Animal Biology, School of Veterinary Medicine                   
Cell and Developmental Biology, Perelman School of Medicine
1:05 Hematopoietic Stem Cell Formation – Lessons from the Embryo
Nancy Speck, PhD
Professor, Cell and Developmental Biology
1:45 Functional Single Cell Genomics: The Importance of Variability
James Eberwine, PhD
Professor of Pharmacology
Co-Director, Penn Genome Frontiers Institute
2:25 BREAK
2:40 Session 3: Reprogramming Cell Fates
Chair: Nancy Speck, PhD
2:45 Experimental and (Patho)physiological Reprogramming in the Adult Liver
Kilang Yanger, PhD
Postdoctoral Fellow, Department of Medicine
3:10 Transdifferentiation of Fibroblasts to Cardiomyocytes
Russ Addis, PhD
Sr. Research Investigator, Cell and Developmental Biology
3:40 Hair Follicle Stem Cells and Skin Regeneration
George Cotsarelis, MD
Chair, Department of Dermatology
4:20 Final Discussion on Cellular Reprogramming
Ken Zaret, PhD

Penn Medicine is one of the world's leading academic medical centers, dedicated to the related missions of medical education, biomedical research, and excellence in patient care. Penn Medicine consists of the Raymond and Ruth Perelman School of Medicine at the University of Pennsylvania (founded in 1765 as the nation's first medical school) and the University of Pennsylvania Health System, which together form a $5.3 billion enterprise.

The Perelman School of Medicine has been ranked among the top five medical schools in the United States for the past 18 years, according to U.S. News & World Report's survey of research-oriented medical schools. The School is consistently among the nation's top recipients of funding from the National Institutes of Health, with $373 million awarded in the 2015 fiscal year.

The University of Pennsylvania Health System's patient care facilities include: The Hospital of the University of Pennsylvania and Penn Presbyterian Medical Center -- which are recognized as one of the nation's top "Honor Roll" hospitals by U.S. News & World Report -- Chester County Hospital; Lancaster General Health; Penn Wissahickon Hospice; and Pennsylvania Hospital -- the nation's first hospital, founded in 1751. Additional affiliated inpatient care facilities and services throughout the Philadelphia region include Chestnut Hill Hospital and Good Shepherd Penn Partners, a partnership between Good Shepherd Rehabilitation Network and Penn Medicine.

Penn Medicine is committed to improving lives and health through a variety of community-based programs and activities. In fiscal year 2015, Penn Medicine provided $253.3 million to benefit our community.


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