Mice cells with permanently and selectively labeled pancreatic acinar cells (left panel, blue-green). At the same time, insulin-producing cells could be followed by a stain specific for insulin (middle panel, red) The two stains do not overlap with each other (right panel), demonstrating that acinar cells do not generate insulin-producing cells after pancreatic injury.

Image Credit: Dorris Stoffers, MD, PhD, University of Pennsylvania School of Medicine

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