Daily variation in blood pressure in normal mice
versus mice in which clock genes have been disrupted. In mice with
normal clock protein (BMAL) function, blood pressure rises during
the morning hours (left). In BMAL knockout mice, the daily variation
in blood pressure vanishes (right).
Image Credit: Annie M. Curtis, PhD, and Garret A. FitzGerald,
MD, University of Pennsylvania School of Medicine; Proceedings
of the National Academy of Sciences.
version (111 KB, JPEG, 300 DPI)