January 17 , 2008
  Penn Researchers Find that Alzheimer’s Molecule is a Smart Speed Bump on the Nerve-Cell Transport Highway
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Differential regulation of dynein and kinesin motor proteins by the microtubule associated protein tau. The Penn group found that dynein, which carries loads towards the interior of the nerve cell, maneuvers around tau; whereas, kinesin, which carries loads towards the outside of the nerve cell, detaches when it encounters tau.

Image Credit: Ram Dixit, PhD, University of Pennsylvania School of Medicine.


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