| Proposed model for the effect of serotonin molecular
signaling in fruitfly clock cells. Serotonin binds to
its receptor, d5-HT1B, setting off a cascade of events
within the cell that involves the clock proteins SGG,
TIM, PER, and CRY, and governs the fly's circadian response
to light. Alternations in the level of the serotonin
receptor affects molecular and behavioral responses
of the fly to light.
Credit: Amita Sehgal, University of Pennsylvania
School of Medicine and Cell Press
|
